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Investigational vaccine does not provide sufficient protection against HIV infection

An investigational HIV vaccine tested in the "Imbokodo" clinical trial conducted in sub-Saharan Africa posed no safety concerns but did not provide sufficient protection against HIV infection, according to a primary analysis of the study data. The Phase 2b proof-of-concept study, which began in November 2017, enrolled 2,637 women ages 18 to 35 years from five countries.

31 Aug 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Self-amplifying RNA (saRNA) is an advanced platform for nucleic acid vaccine development. The backbone is typically derived from an alphaviral genome and encodes a gene of interest (GOI) and a viral replicase that can amplify the genomic and subgenomic RNA.

30 Aug 2021

Northwestern researchers continue investigation on all aspects of COVID-19 pandemic

Northwestern Medicine scientists continue to investigate all aspects of the COVID-19 pandemic: from molecular mechanisms of infection, to child hospitalization and single-dose vaccine response.

28 Aug 2021

Recognizing viral genomes in quick, ‘CRISP’ ways

Researchers from China recently reviewed the latest advancements, applications, and prospects of virus detection using CRISPR-Cas systems.

27 Aug 2021

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

The AIDS Clinical Trials Group, the largest global HIV research network, which has expanded its focus to include evaluating outpatient treatment for COVID-19, today announced positive data for the monoclonal antibody combination therapy BRII-196/BRII-198 from the ACTIV-2 study of Outpatient Monoclonal Antibodies and Other Therapies.

27 Aug 2021

Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

An analysis of data from 1.5 million people has identified 579 locations in the genome associated with a predisposition to different behaviors and disorders related to self-regulation, including addiction and child behavioral problems.

27 Aug 2021

Certain high priority groups more likely to stop taking HIV prevention treatment, study finds

A large, detailed look at patients taking HIV-prevention drug therapy finds strong adherence soon after patients get the prescription, but less consistent use thereafter, particularly among groups considered high priority for receiving the medication.

27 Aug 2021

Study identifies 579 genomic regions associated with predisposition to self-regulating behaviors

Researchers have identified 579 locations in the human genome associated with a predisposition to self-regulation-related behaviors, including addiction and child behavioral problems. With data from 1.5 million people of European descent, the effort is considered to be one of the largest genome-wide association studies to date.

26 Aug 2021

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

Researchers at Albert Einstein College of Medicine and the City University of New York Graduate School of Public Health and Health Policy have been awarded a five-year, $14.5 million grant from the National Institutes of Health to continue leading and expand their research on HIV treatment and care in five Central African nations.

24 Aug 2021

COVID booster shots might be needed in subgroup of HIV-positive individuals

The coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a global pandemic destroying lives and economies. COVID-19 is not curable, so vaccines are the only safeguard during this pandemic.

23 Aug 2021

CUNY SPH and NYC Health Department receive grant to study long-acting injectables for HIV

The National Institute of Mental Health has awarded the CUNY Graduate School of Public Health and Health Policy and the New York City Department of Health and Mental Hygiene a thirty month grant to support long-acting injectable antiretroviral therapy access, uptake, and adherence among people with HIV enrolled in the Ryan White HIV/AIDS Program (hereafter "Ryan White").

23 Aug 2021

HRC Foundation and Us Helping Us launch first national in-home HIV testing program in the U.S.

Today, The Human Rights Campaign Foundation, the educational arm of the nation’s largest lesbian, gay, bisexual, transgender and queer civil rights organization, in partnership with Us Helping Us, launched the United States’ first national in-home HIV testing program centered around reaching communities disproportionately impacted by HIV—Black and Latinx gay, bisexual men and transgender women of color.

23 Aug 2021

Heidelberg researchers focus on developing drugs against flavi- and coronaviruses

New drugs are intended to help stop viral zoonoses - infections that jump from animals to humans. To study suitable inhibitors, Prof. Dr Christian Klein from the Institute of Pharmacy and Molecular Biotechnology of Heidelberg University is receiving funding in the amount of 450,000 euros from the Volkswagen Foundation.

20 Aug 2021

Epidemiology study provides clues for designing new strategies to curb HIV-related mortality in China

In China, HIV-related deaths are on the rise, despite years of efforts by the government to control them. In an effort to overcome this, a new study published in Chinese Medical Journal dug deep into HIV-related data of nearly 30 years.

19 Aug 2021

CUNY SPH and NYC Health Department receive $3.3 million grant to test new HIV intervention

The National Institute of Mental Health has awarded the CUNY Graduate School of Public Health and Health Policy and the New York City Department of Health and Mental Hygiene a five-year, $3.3 million grant to test a new strategy to help people living with HIV achieve viral suppression.

18 Aug 2021

Researchers receive $26.5 million NIH grant to pursue a new strategy for curing HIV

Over the last 40 years, HIV has shifted from a deadly and mysterious virus to one that can be controlled with daily drugs. But attempts to completely eliminate the virus from the bodies of people living with HIV, curing them for good, have failed.

17 Aug 2021

UC Davis Health offers third dose COVID-19 'booster' shots to immunocompromised patients

As COVID-19 cases rise due to the Delta variant, the Centers for Disease Control (CDC) has approved third dose vaccinations for patients whose immune systems are compromised moderately to severely.

17 Aug 2021

Study: Minority groups remain conspicuously absent from pancreatic cancer clinical trials

According to a study published today in Gastroenterology by researchers at Virginia Commonwealth University Massey Cancer Center and University of Florida Health, Black, Hispanic, Indigenous and Asian Americans remain conspicuously absent from pancreatic cancer clinical trials aimed at testing the most recent treatment advances for this deadly disease.

17 Aug 2021

Weill Cornell Medicine receives $28.5 million Martin Delaney Collaboratory grant to lead HIV cure research

Weill Cornell Medicine has been awarded a five-year, $28.5 million Martin Delaney Collaboratory grant from the National Institutes of Health to lead a multi-institutional effort aimed at finding a cure for HIV.

17 Aug 2021

HIV News and Research

Investigational vaccine does not provide sufficient protection against HIV infection

The tale of mRNA vaccines: Turning calamity into opportunity

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Northwestern researchers continue investigation on all aspects of COVID-19 pandemic

Recognizing viral genomes in quick, ‘CRISP’ ways

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

Certain high priority groups more likely to stop taking HIV prevention treatment, study finds

Study identifies 579 genomic regions associated with predisposition to self-regulating behaviors

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

COVID booster shots might be needed in subgroup of HIV-positive individuals

CUNY SPH and NYC Health Department receive grant to study long-acting injectables for HIV

HRC Foundation and Us Helping Us launch first national in-home HIV testing program in the U.S.

Heidelberg researchers focus on developing drugs against flavi- and coronaviruses

Epidemiology study provides clues for designing new strategies to curb HIV-related mortality in China

CUNY SPH and NYC Health Department receive $3.3 million grant to test new HIV intervention

Researchers receive $26.5 million NIH grant to pursue a new strategy for curing HIV

UC Davis Health offers third dose COVID-19 'booster' shots to immunocompromised patients

Study: Minority groups remain conspicuously absent from pancreatic cancer clinical trials

Weill Cornell Medicine receives $28.5 million Martin Delaney Collaboratory grant to lead HIV cure research

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