Precision Medicine News and Research

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Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Advances in personalized medicine allow doctors to select the most promising drugs for certain types of malignant tumors.

24 Mar 2016

Scientists find evidence that amyloid fibrils adopt several distinct architectures in human, animal tissues

Formation of amyloid fibrils is a characteristic feature of neurogenerative diseases like Alzheimer's. As published in the journal Angewandte Chemie, German and American scientists have found evidence that these fibrils adopt several distinct three-dimensional architectures in real patient and animal tissues.

16 Mar 2016

Decreased dietary diversity linked to reduced microbiotic richness

Changes in farming practices over the last 50 years have resulted in decreased agro-diversity which, in turn, has resulted in decreased dietary diversity. The significant impact of this change in dietary richness on human health is the topic of an insightful perspective in Molecular Metabolism by Mark Heiman, MicroBiome Therapeutics and Frank Greenway, Pennington Biomedical Research Center

15 Mar 2016

Study on kidney cancer can help pave way toward more effective personalized medicine

Understanding the complexity of cancer is a major goal of the scientific community, and for kidney cancer researchers this goal just got closer. Dr. Chad Creighton, associate professor of medicine and member of the Dan L Duncan Comprehensive Cancer Center Division of Biostatistics at Baylor College of Medicine, led the study that analyzed close to 900 kidney cancers at the molecular level.

15 Mar 2016

Researchers identify potential drug target in skin for itchy feeling

No matter the trigger -- bug bites, a medication side-effect or an itchy wound -- the urge to scratch can be a real pain. Researchers at the Duke University Medical Center have identified a potential drug target in the skin for that itchy feeling.

14 Mar 2016

Scientists map biological networks of genes to gain new insights on disease mechanisms

Innovative software tools allowed the scientists to construct accurate "maps" of gene networks for about 400 different human cell and tissue types, ranging from immune cells to brain tissues, whereas previous studies were limited to just one or few tissues.

11 Mar 2016

Secretory capacity of human gut does not decline with age, shows study

A breakthrough in basic research and the first comprehensive study on the secretory activity of the human intestine: over a period of eight years, Dr. Dagmar Krüger of the Department of Human Biology at TU Munich has examined more than 2200 specimens from around 450 patients with bowel disease.

10 Mar 2016

Cardiac reprogramming could shrink heart scar tissue, improve patients' heart function

Patients with heart failure often have a buildup of scar tissue that leads to a gradual loss of heart function. In a new study published today in the journal Cell Stem Cell, researchers from the University of North Carolina School of Medicine report significant progress toward a novel approach that could shrink the amount of heart scar tissue while replenishing the supply of healthy heart muscle.

4 Mar 2016

Vanderbilt to lead Direct Volunteers Pilot Studies under Precision Medicine Initiative Cohort Program

Federal officials with the White House and National Institutes of Health announced today that Vanderbilt University Medical Center will lead the Direct Volunteers Pilot Studies under the first grant to be awarded in the federal Precision Medicine Initiative Cohort Program.

27 Feb 2016

Luminex collaborates with University of São Paulo to validate multi-analyte Zika virus assay

Luminex Corporation today announced it is collaborating with the Laboratory of Molecular Evolution & Bioinformatics, Biomedical Sciences Institute, University of São Paulo, Brazil to validate a multi-analyte Zika virus assay developed by Luminex partner, GenArraytion, Inc.

26 Feb 2016

Four molecular subtypes of pancreatic cancer identified

Today, researchers from the Australian Pancreatic Cancer Genome Initiative published a pivotal study in the journal Nature that identified four subtypes of pancreatic cancer.

25 Feb 2016

Current DRG-based cost recovery system appears problematic for patients with complex disorders

A new study by researchers from Charité - Universitätsmedizin Berlin compares the true cost of treating patients with chronic inflammatory bowel disease with costs recoverable under the current German DRG-based system.

24 Feb 2016

Increasing medication adherence: an interview with Dr Alejandro (Alex) Jaimes

Adherence applies to multiple levels of healthcare. Before a drug goes on the market it has to undergo testing in clinical trials: participants take the study drug and report how well the drug works, along with any side effects.

22 Feb 2016

FSU researchers explore new method to decipher genetic data for new prostate cancer treatments

Florida State University researchers are working on new approaches to deciphering genetic data that may lead to new, more targeted prostate cancer treatments.

22 Feb 2016

CHLA, Thermo Fisher Scientific agree to develop NGS-based panel for pediatric cancer research

Children's Hospital Los Angeles and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA's first NGS panel designed to target biomarkers associated with childhood cancers.

19 Feb 2016

UPMC uses simple gene test to personalize medications for patients undergoing heart catheterization

Patients who go to UPMC Presbyterian for heart catheterization and who receive a stent to treat clogged arteries are now being screened with a simple blood test to determine if they have a gene variant that makes them less likely to respond to a blood-thinning medication commonly prescribed after the procedure.

11 Feb 2016

Study shows how structural differences in the brain may relate to behavior differences in males and females

Differences in the neural wiring across development of men and women across ages, matched behavioral differences commonly associated with each of the sexes, according to an imaging-based study from researchers at the Perelman School of Medicine at the University of Pennsylvania published February 1 in Philosophical Transactions of the Royal Society B.

10 Feb 2016

New study finds steep decline in basic science publications

A new study has found a steep decline in the number of scholarly papers about basic science published in leading medical journals in the last 20 years.

3 Feb 2016

New gene cut-and-paste methods help correct disease-causing mutation in animal model

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.