Lungs News and Research

RSS

Immuno-proteomic profiling suggests aberrant immune cell regulation associated with post-COVD-19 infection

A new study investigates the association between the immune system and respiratory complications post-COVID-19 infection.

28 Jan 2022

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

This study showed inhalable Covid-19 mimetic particle carriers as potential, versatile, aerosolizable COVID-19 vaccine candidates if worked on with continued optimization and refinement.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

New approach using RNA therapeutic can fix protein problems in cystic fibrosis

The process of generating proteins from genes is akin to a factory, where workers follow a set of instructions that, ideally, are effective and clear.

27 Jan 2022

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

A new study analyzed whether alveolar epithelial cell necrosis at an early stage SARS-CoV-2 infection and subsequent releases of damage-associated molecular patterns could aggravate COVID-19-associated acute respiratory distress syndrome.

27 Jan 2022

Cedars-Sinai experts conduct a national analysis on COVID-19 lung transplants

The analysis of more than 3,000 lung transplants in the U.S. between Aug. 1, 2020, and Sept. 30, 2021, showed that during the pandemic, 7% of the nation's lung transplants were performed to treat severe, irreversible lung damage caused by COVID-19. More than half of these patients needed ventilators or extracorporeal membrane oxygenation, or ECMO, before their transplant.

27 Jan 2022

French project takes an extra step in the development of nasal vaccine candidate against COVID-19

The development of a protein vaccine candidate for nasal administration has taken another step. Led by the BioMAP research team, from the Infectiology and Public Health (ISP) joint research unit run by INRAE and the Université de Tours, this project, supported by the Ministry of Higher Education, Research and Innovation, and accompanied by the ANRS | Maladies infectieuses émergentes, is moving up a gear.

27 Jan 2022

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

26 Jan 2022

Broad and potent neutralizing activity of human IgG1 LALA antibody against SARS-CoV-2 variants

A new study has focused on the identification, in vitro binding, and potent neutralizing activity of STI-9167 (plutavimab) against live viruses and pseudotype viruses.

25 Jan 2022

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Researchers from Portugal reported a 75% risk reduction in hospitalizations for individuals infected with Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to the Delta variant and a shorter length of stay and lower mortality if hospitalization does occur. Their paper is currently available on the medRxiv* preprint server while undergoing peer review.

24 Jan 2022

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Protein misfolding is a likely culprit in many degenerative disorders. Cystic fibrosis, for instance, is caused by mutations in the CFTR gene that prevent the eponymous protein from assuming its proper configuration.

24 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

A group of researchers used the golden hamster as a model system to better understand the long-term impacts of SARS-CoV-2 infection.

24 Jan 2022

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers have investigated the pathology and inflammatory response to the Delta variant in mice.

24 Jan 2022

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

24 Jan 2022

Study shows monoclonal antibody and antiviral therapy are useful in preventing the severity of SARS-CoV-2 Omicron infection

In a new study, researchers assessed the efficacy of the FDA-approved therapeutic mAbs, as well as to small-molecule antiviral agents against the SARS-CoV-2 Omicron variant in Syrian hamsters.

21 Jan 2022

Cannabidiol found to inhibit SARS-CoV-2 infection in human cells and mice

An interdisciplinary team of researchers from the University of Chicago has found evidence that cannabidiol (CBD), a product of the cannabis plant, can inhibit infection by SARS-CoV-2 in human cells and in mice.

21 Jan 2022

New MRI technology to expand imaging access for patients with implanted medical devices and obesity

New MRI technology, developed by Siemens in collaboration with researchers at The Ohio State University College of Medicine and College of Engineering, will expand imaging access for patients with implanted medical devices, severe obesity and claustrophobia.

21 Jan 2022

Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals

Researchers investigated the effectiveness of the SARS-CoV-2 Omicron-variant induced immunity, whether it is cross-protective against other variants, and if earlier infection with the SARS-CoV-2 Delta variant offers protection against Omicron.

20 Jan 2022

Exploring the interactions between multiple respiratory viruses

A recent report explores the dynamics of viral interference between various respiratory viruses in light of the ongoing COVID-19 pandemic.

19 Jan 2022

Lungs News and Research

Immuno-proteomic profiling suggests aberrant immune cell regulation associated with post-COVD-19 infection

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

New approach using RNA therapeutic can fix protein problems in cystic fibrosis

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

Cedars-Sinai experts conduct a national analysis on COVID-19 lung transplants

French project takes an extra step in the development of nasal vaccine candidate against COVID-19

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

Broad and potent neutralizing activity of human IgG1 LALA antibody against SARS-CoV-2 variants

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Study shows monoclonal antibody and antiviral therapy are useful in preventing the severity of SARS-CoV-2 Omicron infection

Cannabidiol found to inhibit SARS-CoV-2 infection in human cells and mice

New MRI technology to expand imaging access for patients with implanted medical devices and obesity

Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals

Exploring the interactions between multiple respiratory viruses

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Latest News