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Study reports new monoclonal antibodies with broad neutralizing capabilities against betacoronaviruses (including SARS-CoV-2)

In a paper published on the bioRxiv* preprint server, researchers report new monoclonal antibodies that target the S2 subunit and that have broad neutralization activity against several betacoronaviruses.

13 May 2021

Black fungus complicates India's COVID pandemic

India faces a global health crisis as the number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections reaches over 23.7 million. As India's health system buckles with increased admissions and a lack of resources, another health threat has emerged.

13 May 2021

New drug-like compound could effectively block a critical step in malaria parasite life cycle

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

12 May 2021

HIV patients are more likely to die from COVID-19 infection

Over the past year, studies have revealed that certain pre-existing conditions, such as cancer, diabetes and high blood pressure, can increase a person's risk of dying from COVID-19.

12 May 2021

Evolutionary-spreading model predicts another devastating COVID-19 peak around July 2021

The emergence of this variant highlighted the uneven pace of mutation and selection of variants. New bioinformatics tools are the need of the hour to clarify this and confirm a dynamic evolution by tracking the mutation rates of the spike protein. It generally takes 1 – 6 months for current variants causing COVID-19 case peaks and deaths to survive the pressure of selection.

11 May 2021

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

A new approach to tackling viruses by targeting the 'control center' in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defense against future pandemics, according to new research at the University of Birmingham.

11 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Study: Novavax Covid-19 vaccine is efficacious against the B.1.351 South African variant

The published data provide additional detail of an initial analysis conducted in January, while more robust data from a complete analysis of the study was subsequently shared in March 2021.

6 May 2021

SARS-CoV-2 is activated for fusion by a broad range of proteases, finds study

A team of researchers from the University of Virginia, USA, used single-virus fusion experiments with exogenously controlled proteases to investigate the mechanism of activation directly. They found that the subcellular location of entry depends on the protease activity of the various components, and parallel pathways are possible.

6 May 2021

Telemedicine is a tool — not a replacement for your doctor’s touch

Earlier in the pandemic it was vital to see doctors over platforms like Zoom or FaceTime when in-person appointments posed risks of coronavirus exposure. Insurers were forced — often for the first time — to reimburse for all sorts of virtual medical visits and generally at the same price as in-person consultations.

6 May 2021

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

Researchers from the University of Liverpool have shown the potential of repurposing an existing and cheap drug into a long-acting injectable therapy that could be used to treat Covid-19.

5 May 2021

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Despite decades of research and investment, the genetic underpinnings of Alzheimer's disease are still largely unknown, stymieing drug development and early diagnosis efforts.

5 May 2021

Certain parts of the innate immune response can be trained in response to HIV

Immunity often calls to mind the adaptive immune response, made up of antibodies and T cells that learn to fight specific pathogens after infection or vaccination.

5 May 2021

Stem cell therapy for COVID-19 and ARDS

In a review paper recently uploaded to the journal Biomedicine & Pharmacotherapy by Mahendiratta et al. (May 2021) the applicability of stem cells in treating severe SARS-CoV-2 infection is investigated, with regard to ARDS therapy.

5 May 2021

Special issue of JANAC summarizes 40 years of nursing science throughout the HIV epidemic

From the very beginning of the AIDS epidemic in 1981, nurses have been at the forefront of patient care, advocacy, and research.

5 May 2021

Researchers improve HIV care using mobile gaming application

Researchers at the University of North Carolina at Chapel Hill and Duke University improved HIV care by gamifying it with a mobile gaming application.

4 May 2021

ATS publishes new clinical practice guideline on community-acquired pneumonia

In its latest clinical practice guideline on community-acquired pneumonia the American Thoracic Society's guidelines panel addresses the use of nucleic acid-based testing for non-influenza viral pathogens.

4 May 2021

New findings on the support and barriers to combat TB in high-burden countries

Nine out of ten cases of tuberculosis appear in 30 identified low and middle-income countries, each of which has a national tuberculosis programme.

3 May 2021

SARS-CoV-2 spike mutations during transmission among humans and to animals

A fascinating new study discusses the 40 mutations that are seen on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and their potential effects on viral biology.

3 May 2021

Detecting rare blood clots was a win, but US vaccine safety system still has gaps

The quick detection of an ultra-rare blood clotting reaction in some Covid-19 vaccine recipients showed the power of a federal warning system for vaccine safety issues, but experts worry that blind spots in the program could hamper detection of other unexpected side effects.

3 May 2021

HIV News and Research

Study reports new monoclonal antibodies with broad neutralizing capabilities against betacoronaviruses (including SARS-CoV-2)

Black fungus complicates India's COVID pandemic

New drug-like compound could effectively block a critical step in malaria parasite life cycle

HIV patients are more likely to die from COVID-19 infection

Evolutionary-spreading model predicts another devastating COVID-19 peak around July 2021

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

Natural products a rich source for novel antiviral compounds

Study: Novavax Covid-19 vaccine is efficacious against the B.1.351 South African variant

SARS-CoV-2 is activated for fusion by a broad range of proteases, finds study

Telemedicine is a tool — not a replacement for your doctor’s touch

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Certain parts of the innate immune response can be trained in response to HIV

Stem cell therapy for COVID-19 and ARDS

Special issue of JANAC summarizes 40 years of nursing science throughout the HIV epidemic

Researchers improve HIV care using mobile gaming application

ATS publishes new clinical practice guideline on community-acquired pneumonia

New findings on the support and barriers to combat TB in high-burden countries

SARS-CoV-2 spike mutations during transmission among humans and to animals

Detecting rare blood clots was a win, but US vaccine safety system still has gaps

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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