Receptor News and Research

RSS

Pre-malignant mammary lesions in dogs and humans display many of the same characteristics

...a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine.

16 Nov 2007

Kisspeptin and GPR54 may be the future of ovarian cancer treatment

Kisspeptin and its receptor GPR54 predict a favourable clinical outcome in women with ovarian carcinoma, and are specific for the clear cell carcinoma subtype, research published this week in the online open access journal, BMC Medicine, reveals.

16 Nov 2007

How inhibitor-of-apoptosis chemicals kill tumors

Chemical compounds specially designed to neutralize proteins that would otherwise allow tumor cells to cheat death have been recognized for some time by scientists as a promising new avenue for cancer therapy.

16 Nov 2007

New clinical standards on the treatment of patients with cystic fibrosis

New clinical standards on the treatment of patients with cystic fibrosis (CF) have been released following an exhaustive review of all available literature.

16 Nov 2007

CD200 stifles anti-tumor immunity

The prognosis for individuals with metastatic melanoma (MM) is not good. Therapeutic strategies to enhance the immune response have some clinical benefit; however, most patients eventually succumb to progressive disease, in part because their immune cells known as dendritic cells (DCs) fail to sustain an effective antitumor T cell immune response.

16 Nov 2007

Low doses of arsenic disrupt activity of development hormone

A team of Dartmouth Medical School (DMS) researchers has determined that low doses of arsenic disrupt the activity of a hormone critical in development. The finding is further evidence that arsenic at low doses (at levels found in U.S. drinking water in some areas) can be harmful.

15 Nov 2007

New drug may restore memory with Alzheimer's disease

A 2006 study by MetLife found that adults over age 55 fear Alzheimer's disease more than cancer, and with good reason. Alzheimer's creeps up on patients and their families, robbing more than half of all Americans over age 85 of their memory and ability to care for themselves.

14 Nov 2007

Two proteins may be survival markers in some breast cancers

New research suggests that the presence or absence of two proteins may be important markers for long-term survival in some breast-cancer patients.

13 Nov 2007

Brain may have important influences on glucose metabolism and insulin action

An appetite-suppressing chemical also improves glucose tolerance and lowers insulin levels in obese and diabetic mice, researchers report in the November issue of Cell Metabolism, a publication of Cell Press.

13 Nov 2007

Discovery of key pathway, potential drug targets in autoinflammatory disease

Molecular biologists at Jefferson's Kimmel Cancer Center in Philadelphia have detailed the cascade of cellular events behind some potentially dangerous autoinflammatory diseases.

13 Nov 2007

Abnormal immune cells may cause unprovoked idiopathic anaphylaxis

Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis--a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing.

13 Nov 2007

Interaction between nicotine and alcohol impacts learning

The interaction between nicotine and alcohol, two of the most abused and co-abused drugs, can impact a person's ability to learn and could have implications for treating addiction, according to researchers at Temple University.

6 Nov 2007

Tezosentan does not appear to improve symptoms for patients with acute heart failure

The medication tezosentan, which was thought could be beneficial for the treatment of acute heart failure, did not improve breathlessness or reduce the risk of fatal or nonfatal cardiovascular events, according to a study in the November 7 issue of JAMA.

6 Nov 2007

Brain appears to play important role in glucose metabolism and insulin action

6 Nov 2007

Novel approaches to hypertension control

A hypertension vaccine could be an important alternative to conventional drug therapy because of patients' inconsistent drug intake - if further research supports results from a small study testing the safety and tolerability of a vaccine.

6 Nov 2007

Prazosin curbs brain damage from post-traumatic stress disorder

A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia.

6 Nov 2007

More effective method of treating high blood pressure

Scientists at Robarts Research Institute have developed a simplified and more effective method of treating high blood pressure.

6 Nov 2007

Osteopontin-c is a good biomarker of breast cancer.

Researchers have identified a molecule that may be more accurate than existing biological signposts used to predict which breast cancers will develop into advanced forms of the disease.

6 Nov 2007

Hepatitis C virus found to spread directly from cell to cell by-passing antibodies

Scientists looking for an effective treatment for Hepatitis C may face an even bigger task than anticipated. Recent studies looking into how the virus spreads in liver tumour cells have demonstrated that the virus uses two different routes, which may explain why the body's natural occurring antibodies are ineffective at controlling the virus.

5 Nov 2007

Common blood pressure medications ACEIs and ARBs provide equal control

Two common classes of blood pressure medications – angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) – are equally effective at controlling high blood pressure, according to a report released by the Agency for Healthcare Research and Quality, part of the U.S. Department of Health and Human Services.

5 Nov 2007