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Researchers identify genetic mutation that causes fatal response to HAV infection

Researchers have identified a genetic mutation that caused an 11-year-old girl to suffer a fatal reaction to infection with the Hepatitis A virus.

18 Jun 2019

Henry Ford Cancer Institute treats its first patient with CAR T-cell therapy

Henry Ford Cancer Institute has treated its first patient with CAR T-cell therapy, an approach that uses engineered cells from a patient's immune system to destroy cancer.

18 Jun 2019

Scientists develop new class of drugs to treat hereditary kidney disease

Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.

18 Jun 2019

Miracle machine makes heroic rescues — and leaves patients in limbo

The latest miracle machine in modern medicine — whose use has skyrocketed in recent years — is saving people from the brink of death: adults whose lungs have been ravaged by the flu; a trucker who was trapped underwater in a crash; a man whose heart had stopped working for an astonishing seven hours.

18 Jun 2019

Ochsner Hospital for Children joins national consortium to provide solutions for hypoplastic left heart syndrome

Mayo Clinic's Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome and Ochsner Hospital for Children are collaborating within a consortium to provide solutions for patients with hypoplastic left heart syndrome, a rare and complex form of congenital heart disease in which the left side of the heart is severely underdeveloped.

17 Jun 2019

Topical cream found to be effective in reversing the effects of vitiligo

A nationwide phase II clinical trial, coordinated out of Tufts Medical Center in Boston, has found that a topical cream was extremely effective in reversing the effects of vitiligo, a relatively common autoimmune disease that causes loss of skin pigmentation.

17 Jun 2019

$VITALE study: High-dose vitamin D effective in lowering fracture rates after kidney transplantation$

VITALE study: High-dose vitamin D effective in lowering fracture rates after kidney transplantation

Lead VITALE investigator Dr Marie Courbebaisse (Paris, France), commented, Our study shows that currently recommended doses of vitamin D are not sufficient to protect patients from the risk of fracture after kidney transplantation.

17 Jun 2019

Augusta vision scientist receives grant to learn more about keratoconus’ causes and treatments

It's an eye condition where genetics and environmental factors like ultraviolet light and vigorous eye rubbing conspire to make the usual curvature of the cornea more pointy, leaving us with double vision and nearsighted.

17 Jun 2019

Warning issued by FDA after patient dies following fecal transplant

A warning from the U.S FDA was issued yesterday after a patient died due to receiving a fecal transplant that contained drug-resistant bacteria.

14 Jun 2019

Virus employs powerful strategy to inhibit natural killer cell function

The virus responsible for chickenpox and shingles employs a powerful strategy of immune evasion, inhibiting the ability of natural killer cells to destroy infected cells and produce molecules that help control viral infection, according to a study published June 13 in the open-access journal PLOS Pathogens by Allison Abendroth of the Discipline of Infectious Diseases and Immunology in the Charles Perkins Centre at the University of Sydney, and colleagues.

From PLOS ONE 14 Jun 2019

One-fifth of U.S. surgeons still 'overusing' riskier method to create kidney dialysis access, study finds

Long-term hemodialysis is a lifesaver for approximately half a million patients in the United States with kidney failure (also known as end-stage renal disease, or ESRD) who are either waiting on or unsuitable for a kidney transplant.

From Johns Hopkins Medicine 14 Jun 2019

More screening and new treatments needed for sickle cell disease

The promise of new treatments for sickle cell disease, a group of inherited red blood cell disorders, has never been so great, but it will only be realized if there is constant investment in health policies such as programs for screening newborns, especially in sub-Saharan Africa, where most cases occur.

13 Jun 2019

Patients receiving drug therapy before LVAD implantation have high risk of right-sided heart failure

Patients with left-sided heart failure who get implanted devices to improve the pumping of their hearts may be more likely to develop heart failure on the opposite side of their hearts if they are pre-treated with off-label selective vasodilator drugs, according to new research published in Circulation: Heart Failure, an American Heart Association journal.

11 Jun 2019

Unhealthy gut microbiome may make breast cancers more aggressive finds study

A new study from the researchers at the University of Virginia Cancer Center connects an unhealthy gut microbiome with breast cancer that can become invasive and spread to other organs faster. The results of the study were published in the latest issue of the journal Cancer Research.

10 Jun 2019

Mini-biographies help clinicians connect with patients

Bob Hall was recovering from yet another surgery in March 2014 when a volunteer walked into his hospital room. It had been a rocky recovery since his lung transplant three months earlier at the William S. Middleton Memorial Veterans Hospital in Madison, Wis.

10 Jun 2019

CGM evaluations in long-term islet transplant recipients show near-normal glycemic profiles

Continuous glucose monitoring evaluations in islet transplant recipients who have been insulin independent for an average of 10 years show near-normal glycemic profiles and time-in-range metrics, according to data presented by the Diabetes Research Institute at the University of Miami Miller School of Medicine.

10 Jun 2019

Opioid epidemic increases proportion of hearts transplanted from overdose death donors

The confluence of two major health crises—the opioid epidemic and organ shortage—has moved surgeons to consider transplanting organs deemed as less than "perfect" in an effort to expand the donor pool and save more lives, according to research published online today in The Annals of Thoracic Surgery, published by Elsevier.

7 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Gut bacteria linked to metabolic changes and autism in new study

Researchers have made an important discovery that may explain how gut bacteria could contribute to autism-like behaviors.

31 May 2019

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

A method of growing blood stem cells in the laboratory has been developed by researchers at Stanford University and the University of Tokyo, in a breakthrough that could spare some people with blood and immune disorders from the side effects of intensive chemotherapy and radiotherapy.

31 May 2019

Transplant News and Research

Researchers identify genetic mutation that causes fatal response to HAV infection

Henry Ford Cancer Institute treats its first patient with CAR T-cell therapy

Scientists develop new class of drugs to treat hereditary kidney disease

Miracle machine makes heroic rescues — and leaves patients in limbo

Ochsner Hospital for Children joins national consortium to provide solutions for hypoplastic left heart syndrome

Topical cream found to be effective in reversing the effects of vitiligo

VITALE study: High-dose vitamin D effective in lowering fracture rates after kidney transplantation

Augusta vision scientist receives grant to learn more about keratoconus’ causes and treatments

Warning issued by FDA after patient dies following fecal transplant

Virus employs powerful strategy to inhibit natural killer cell function

One-fifth of U.S. surgeons still 'overusing' riskier method to create kidney dialysis access, study finds

More screening and new treatments needed for sickle cell disease

Patients receiving drug therapy before LVAD implantation have high risk of right-sided heart failure

Unhealthy gut microbiome may make breast cancers more aggressive finds study

Mini-biographies help clinicians connect with patients

CGM evaluations in long-term islet transplant recipients show near-normal glycemic profiles

Opioid epidemic increases proportion of hearts transplanted from overdose death donors

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Gut bacteria linked to metabolic changes and autism in new study

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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