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Findings suggest that the cross-linking of fibrin proteins is key to reducing blood clot formation

Researchers have found that the y cross-chain structure of fibrin proteins is essential to stabilizing blood clots that can lead to harmful embolism formation.

29 Jun 2021

Study explores structure, activity, and inhibition of TMPRSS2 implicated in SARS-CoV-2 activation

Researchers from Canada recently presented an efficient strategy for recombinant production of enzymatically active TMPRSS2 ectodomain, enabling enzymatic characterization and the 1.95 Å X-ray crystal structure. Their work is published on the bioRxiv* preprint server while awaiting peer-review.

29 Jun 2021

New spider web mechanism kills pathogens and virus responsible for COVID-19

Immunologists at McMaster University have discovered a previously unknown mechanism which acts like a spider web, trapping and killing pathogens such as influenza or SARS-CoV-2, the virus responsible for COVID-19.

29 Jun 2021

SARS-CoV-2 infection induces accumulation of lipids and N-proteins

Scientists from the Netherlands and the US recently studied the localization of the SARS-CoV-2 proteins in postmortem lung tissues of COVID-19 patients and in SARS-CoV-2 infected Vero cells that were processed identically. The research is posted to the bioRxiv* preprint server, prior to peer review.

29 Jun 2021

Aerosol generated by playing wind instruments is less than that produced when vocalizing

Aerosol generated by playing woodwind and brass instruments is less than that produced when vocalizing (speaking and singing) and is no different than a person breathing, new research has found.

29 Jun 2021

Specific lung cell exhibits immune properties and improves respiratory viral disease outcomes

Researchers at Children's Hospital of Philadelphia have discovered that a specific type of lung cell exhibits unconventional immune properties and may contribute to the outcome of respiratory viral infections.

28 Jun 2021

Researchers determine molecular structure of bacterial protein complex critical for tuberculosis

Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a major threat to global health security, and has been declared by the World Health Organization as a global health emergency.

25 Jun 2021

New artificial intelligence system could lead to improved ways to control high ozone problems

Ozone levels in the earth's troposphere (the lowest level of our atmosphere) can now be forecasted with accuracy up to two weeks in advance, a remarkable improvement over current systems that can accurately predict ozone levels only three days ahead.

25 Jun 2021

Researchers decode humans’ survival from historical coronavirus outbreaks

An international team of researchers co-led by the University of Adelaide and the University of Arizona has analyzed the genomes of more than 2,500 modern humans from 26 worldwide populations, to better understand how humans have adapted to historical coronavirus outbreaks.

25 Jun 2021

Scientists identify new virulence mechanism for a surface protein on pneumonia-causing bacteria

A bout with flu virus can be hard, but when Streptococcus pneumonia enters the mix, it can turn deadly.

24 Jun 2021

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

A new analysis of current data indicates that remdesivir does not show efficacy in regulating the severity of the illness.

23 Jun 2021

SARS-CoV-2 infection and transmission in the North American deer mouse

A recent study conducted in Canada reports that the North American deer mouse can be infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from humans.

23 Jun 2021

Natural compound myricetin shows antiviral potential against SARS-CoV-2

New findings from a team of Chinese researchers suggest natural compounds — specifically the flavonoid myricetin — could also be a potential drug candidate for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

23 Jun 2021

At Texas border, pandemic’s high toll lays bare gaps in health and insurance

Alfredo "Freddy" Valles was an accomplished trumpeter and a beloved music teacher for nearly four decades at one of the city's poorest middle schools.

23 Jun 2021

Study provides treatment guidance for children and adolescents with multisystem inflammatory syndrome

An analysis conducted by a group of investigators including Tamara Bradford, MD, Associate Professor of Pediatrics at LSU Health New Orleans School of Medicine, found that children and adolescents with Multisystem inflammatory syndrome in children (MIS-C) initially treated with intravenous immune globulin (IVIG) plus glucocorticoids had a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

22 Jun 2021

Albumin supplementation improves human fertility, fights infection

A new University of California, Irvine-led study reveals albumin (Alb), among the most abundant proteins in the body, activates a proton channel (hHv1), also widespread in the body, giving sperm the ability to penetrate and fertilize an egg, and allowing white blood cells to secrete large amounts of inflammatory mediators to fight infection.

22 Jun 2021

Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

In a cancer that has not seen new targeted therapies for over 20 years, MUSC Hollings Cancer Center researcher and oncologist Nancy Klauber-DeMore, M.D., is pioneering new discoveries.

22 Jun 2021

Dual-antibody combination therapies effective against SARS-CoV-2 variants in animal study

COVID-19 therapies made from antibodies often are given to patients who are at high risk of severe illness and hospitalization. However, there have been nagging questions about whether such antibody therapies retain their effectiveness as worrisome new virus variants arise.

21 Jun 2021

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

A team led by researchers at Newcastle University, UK has successfully created a model of the cells found in the lungs that can be used to replicate how COVID-19 infects the airways.

21 Jun 2021

New method accurately detects virulent infections in advance

When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy.

21 Jun 2021

Lungs News and Research

Findings suggest that the cross-linking of fibrin proteins is key to reducing blood clot formation

Study explores structure, activity, and inhibition of TMPRSS2 implicated in SARS-CoV-2 activation

New spider web mechanism kills pathogens and virus responsible for COVID-19

SARS-CoV-2 infection induces accumulation of lipids and N-proteins

Aerosol generated by playing wind instruments is less than that produced when vocalizing

Specific lung cell exhibits immune properties and improves respiratory viral disease outcomes

Researchers determine molecular structure of bacterial protein complex critical for tuberculosis

New artificial intelligence system could lead to improved ways to control high ozone problems

Researchers decode humans’ survival from historical coronavirus outbreaks

Scientists identify new virulence mechanism for a surface protein on pneumonia-causing bacteria

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

SARS-CoV-2 infection and transmission in the North American deer mouse

Natural compound myricetin shows antiviral potential against SARS-CoV-2

At Texas border, pandemic’s high toll lays bare gaps in health and insurance

Study provides treatment guidance for children and adolescents with multisystem inflammatory syndrome

Albumin supplementation improves human fertility, fights infection

Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

Dual-antibody combination therapies effective against SARS-CoV-2 variants in animal study

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

New method accurately detects virulent infections in advance

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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