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Innovative approach to measure acetaminophen in human urine

In recent years, the excessive use of acetaminophen (APAP) has become a significant human hazard and social burden.

16 Oct 2024

Epigenomic dynamics shape human brain development and neuropsychiatric disorder risks

Researchers investigate chromatin conformational and epigenomic reorganization during the development of the prefrontal cortex and hippocampus.

14 Oct 2024

Liraglutide activates key brain circuits to trigger weight loss in obesity

Researchers uncover how liraglutide targets specific brain regions to suppress appetite and promote significant weight loss through GLP-1 receptor activation.

23 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024

Extraordinary cell division mechanism discovered in common dental plaque bacteria

One of the most diverse ecosystems on the planet is closer than you think -; right inside your mouth. Your mouth is a thriving ecosystem of more than 500 different species of bacteria living in distinct, structured communities called biofilms.

2 Sep 2024

AmelHap: A honeybee haplotype map

Beebytes is very happy to have achieved its first publication, the development of a ‘HapMap’ for honey bees, in collaboration with the Roslin Institute, the University of the Basque Country in Spain, and the National Research Institute for Agriculture, Food and the Environment (INRAE) in France.

From Beebytes Analytics 30 Aug 2024

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

A study in Nature Neuroscience found that both neurons and oligodendrocytes contribute to amyloid-β plaque burden in Alzheimer's disease, highlighting new therapeutic targets.

7 Aug 2024

Genetic loss of miR-205 boosts mammary gland development in mice, reveals new insights into breast cancer suppression

Genetic loss of miR-205 in mice enhances mammary gland development and branching, challenging previous lethality findings and highlighting its onco-suppressive functions.

30 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

VA Tech discovers new way to genetically control mosquitoes

Virginia Tech researchers have found a new way to identify genetic targets useful for control of mosquito populations, potentially offering an alternative to insecticides.

23 Jul 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Researchers compared the distribution of sialic acid receptors in the respiratory tract and mammary glands of dairy cattle naturally infected with the highly pathogenic avian influenza A(H5N1) virus.

18 Jul 2024

New brain targets for GLP1-based obesity drugs may reduce weight without nausea

Researchers identified distinct hindbrain GLP1R neurons driving satiety and aversion, offering new targets for effective, side-effect-free obesity treatments.

14 Jul 2024

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Chromosome 18q deletion (18q del) syndromeis a rare genetic condition disorder, affecting approximately 1 in 40,000 to 55,000 individuals, caused by the deletion of genetic material on the long arm of chromosome 18.

11 Jul 2024

Decoding cerebellar neural patterns in movement disorders

The cerebellum is a region of the brain that helps us refine our movements and learn new motor skills.

3 Jul 2024

High-fat diet triggers anxiety in male rats through gut-brain axis disruption

Researchers investigate the impact of a high-fat diet on gut microbiome diversity and its effects on anxiety-related symptoms.

20 Jun 2024

Researchers investigate the gene-brain-behavior link in autism using generative machine learning

Researchers used 3D transport-based morphometry to visualize brain changes linked to 16p11.2 CNV, achieving high prediction accuracy and advancing autism precision medicine.

18 Jun 2024

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.

4 Jun 2024

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

UNIGE's synthetic anticoagulant provides reliable alternative to heparin

Anticoagulant treatments are crucial for managing many conditions, such as heart disease, stroke and venous thrombosis.

30 Apr 2024