Polymerase News and Research

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Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy."

10 May 2024

Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation

Modified ketogenic diet modulates gut microbiome, inflammatory markers, and brain-related miRNAs in autistic children, correlating with improved behavioral symptoms. The diet increases beneficial gut bacteria and reduces inflammatory cytokines and BDNF levels.

9 May 2024

New Quartet nanocage vaccine shows promise against coronavirus variants

Researchers have developed a novel vaccination approach using Quartet nanocages that display receptor-binding domains (RBDs) from different sarbecoviruses, showing enhanced immune responses and potential protection against diverse coronavirus strains including SARS-CoV-2 and its variants.

8 May 2024

Vitamin D receptor polymorphism found to influence COVID-19 severity

Researchers compared SNPs in the vitamin D receptor (VDR) gene between mild and severe COVID-19 patients.

7 May 2024

Study links early-life tobacco exposure to accelerated aging, urging preventive action

A recent study in Science Advances found that early-life tobacco exposure, including in-utero and early smoking initiation, accelerates biological aging, emphasizing the importance of reducing exposure to improve health outcomes.

6 May 2024

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Researchers discuss current evidence on Candida auris, an emerging multidrug-resistant yeast.

6 May 2024

Gut microbiome study challenges established cancer biomarkers, identifies new bacterial links to colorectal cancer

Study identified that several specific bacterial species were significantly associated with colorectal cancer, challenging previous assumptions about established biomarkers once adjusted for important covariates.

1 May 2024

Avian flu crosses species, infecting cats and cattle in Texas and Kansas

A study in the CDC's Emerging Infectious Disease Journal reports the spread of H5N1 avian influenza among cats and dairy cattle in Texas and Kansas, showing systemic illness in cattle and significant fatalities in cats exposed to the virus through infected milk.

1 May 2024

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria.

30 Apr 2024

Do SARS-CoV-2 infections cause long-term loss of smell and taste?

The long-term smell and taste-associated outcomes of coronavirus disease 2019 (COVID-19) using validated psychophysical tests.

29 Apr 2024

Did California's pediatric COVID-19 vaccination program reduce reported cases and hospitalizations?

Changes in the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related hospitalizations.

26 Apr 2024

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Study investigated whether SARS-CoV-2 lingers in tissues after COVID-19 recovery and if it's linked to long COVID symptoms. They found viral RNA in various organs, and its presence correlated with long COVID symptoms.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Study discovers hidden mechanism behind rapid COVID variants

The SARS-CoV-2 virus that causes COVID has the unsettling ability of often generating variants of itself. Other viruses also mutate, but as SARS-CoV-2 quickly spread throughout the entire human population during the pandemic, killing millions, the virus' dynamic evolution posed a serious problem: it repeatedly challenged our bodies' immune response fighting the virus and hindered the process of getting updated vaccines ready.

23 Apr 2024

Polymerase News and Research

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation

New Quartet nanocage vaccine shows promise against coronavirus variants

Vitamin D receptor polymorphism found to influence COVID-19 severity

Study links early-life tobacco exposure to accelerated aging, urging preventive action

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Gut microbiome study challenges established cancer biomarkers, identifies new bacterial links to colorectal cancer

Avian flu crosses species, infecting cats and cattle in Texas and Kansas

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Do SARS-CoV-2 infections cause long-term loss of smell and taste?

Did California's pediatric COVID-19 vaccination program reduce reported cases and hospitalizations?

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Study discovers hidden mechanism behind rapid COVID variants

Does diabetes increase the risk of long COVID?

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

CDC report: Persistent measles importations challenge U.S. elimination efforts

Research confirms no association between SARS-CoV-2 and childhood asthma diagnoses

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

SARS-COV-2 infection not linked to increased risk of asthma development in pediatric patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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