Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

CVD-21: A novel instrument for predicting and monitoring cardiovascular disease

Researchers at Uppsala University have developed an instrument that makes it possible to measure 21 biomarkers for cardiovascular disease simultaneously with great precision by means of a simple blood test.

15 Nov 2023

Microglia found to play crucial role in early human brain development

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development.

14 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Scientists at deCODE genetics, a subsidiary of Amgen, have published a study on actionable genotypes detected in the Icelandic population and their association with lifespan.

8 Nov 2023

Proteomic study pinpoints potential biomarkers for long-COVID diagnosis and persistent health impacts

A two-year longitudinal study highlights proteomic changes in long-COVID patients, revealing potential biomarkers for diagnosis and shedding light on the persistent physiological challenges faced by survivors.

7 Nov 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

Common chemical label shields proteins from degradation

Researchers from the University of Bergen (UiB) have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.

27 Oct 2023

Single-cell proteomics – when mass spectrometry revolutionizes biomedical research

In the latest episode of the OMG Omx podcast, Bruker's Kate Stumpo talks to Nikolai Slavov about the incredible potential of mass spectrometry proteomics in biomedical research.

From Bruker Life Sciences Mass Spectrometry 27 Oct 2023

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Integrated liquid-biopsy proteomics with single-cell transcriptomics from ocular cell types.

24 Oct 2023

Utilizing Biomarkers in Cancer Prevention, Diagnosis, and Treatment

In this interview, Grace Liu from Sino Biological discusses the crucial role of biomarkers in cancer prevention and diagnosis and how they can help guide treatment decisions.

From Sino Biological Inc. 24 Oct 2023

Stanford Medicine researchers find new way to measure ocular aging

Using a technique they developed for studying eye fluid, Stanford Medicine researchers and their collaborators have found a way to measure ocular aging, opening avenues for treatment of numerous eye diseases.

19 Oct 2023

Graphene oxide offers a promising new approach to treating Alzheimer's disease

A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer’s patients. Researchers at Chalmers University of Technology, have now shown that yeast cells that accumulate these misfolded amyloid peptides can recover after being treated with graphene oxide nanoflakes.

9 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Graphene oxide nanoflakes may help treat Alzheimer's disease

A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer's patients.

4 Oct 2023

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a PhD student in the Institute of Chemical Biology EPSRC Centre for Doctoral Training (CDT) in Chemical Biology, at Imperial College London.

From Ubiquigent Limited 4 Oct 2023

Eat by the clock: How meal timing tunes your liver's circadian rhythm

A study in Nature Communications delves into how the liver's circadian clock responds to meal timing, impacting fat metabolism and other bodily processes. The research underscores the intricate network that contributes to liver's diurnal rhythms, regulated by protein phosphorylation and nutrient availability.

2 Oct 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

Keck School of Medicine of USC to focus on Hispanic patients with NAFLD in multi-omics study

The Keck School of Medicine of USC has received funding from the National Institutes of Health as part of a five-year, $50.3 million "multi-omics" study of human health and disease involving six sites.

26 Sep 2023

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023