Biochemistry

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Scientists develop maps of two melatonin receptors vital for sleep, other biological processes

An international team of researchers used an X-ray laser at the Department of Energy’s SLAC National Accelerator Laboratory to create the first detailed maps of two melatonin receptors that tell our bodies when to go to sleep or wake up and guide other biological processes.

26 Apr 2019

CircRNAs bind to dsRNA-activated protein kinase which is linked to innate immunity

Covalently closed circular RNAs are produced by precursor mRNA back-splicing the exons of thousands of genes in eukaryotes.

26 Apr 2019

Prokaryotic transport protein transports both left-handed and right-handed aspartate efficiently

Many biomolecules come in two versions that are each other's mirror image, like a left and a right hand. Cells generally use the left-hand version of amino acids to produce proteins, and uptake mechanisms were thought to share this preference.

26 Apr 2019

Bentham Science's new volume delves into specific avenues of applied NMR studies

Bentham Science's seventh volume of Applications of NMR Spectroscopy, published by Bentham Science Publishers covers NMR methods in proteomics and metabolomics, and nucleic acid biochemistry.

26 Apr 2019

Coastal trenches, inland volcanoes remove 19% more CO2 than previously thought

Up to about 19 percent more carbon dioxide than previously believed is removed naturally and stored underground between coastal trenches and inland chains of volcanoes, keeping the greenhouse gas from entering the atmosphere, according to a study in the journal Nature.

25 Apr 2019

New fluorescence-based method accurately determines strength of Lewis acids

York University chemists have invented a new fluorescence-based method for accurately determining the strength of a range of Lewis acids, which could one day be used to help purify pharmaceutical drugs, improve industrial processes and explore next-generation technologies, according to a new chemistry study.

25 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Synthesizing Modified and Pharmaceutically Relevant Peptides

In this interview, CEM Corporation talks to News-Medical Life Sciences about using their product the Liberty Blue for Automated High-Efficiency Solid Phase Peptides Synthesis of Modified and Pharmaceutically Relevant Peptides.

From CEM Corporation - Life Science 24 Apr 2019

Hole-forming protein could help control cancer growth

Sometimes cells need to die. The process of cell death is encoded within the genome of all higher organisms to kill off cancerous cells, and as a normal part of development to shape a mass of embryonic cells into the organism it will become.

22 Apr 2019

Nominations invited for prestigious awards at Pittcon Conference & Expo 2020

Nominate a colleague for one of our prestigious awards.

From Pittcon 19 Apr 2019

New discovery transforms conventional microfluidics into open-space microfluidics

Microfluidics refers to the manipulation of fluids in microscale devices. Commonly called "labs on a chip," microfluidic systems are used to study and analyze very small-scale chemical or biological samples, replacing the extremely expensive and cumbersome instruments used for traditional biological analyses.

19 Apr 2019

A comprehensive, centralized database of bovine milk compounds

Milk is a staple of the human diet, full of key nutrients such as protein, carbohydrates, fats, and vitamins. Cow's milk in particular is one of the most-used dairy products globally, with over 800 million tons produced annually according to the United Nations Food and Agriculture Organization.

17 Apr 2019

New bandage-like biosensor collects and analyzes sweat

Like other biofluids, sweat contains a wealth of information about what's going on inside the body. However, collecting the fluid for analysis, usually by dripping or absorbing it from the skin's surface, can be time-consuming and messy.

17 Apr 2019

Ensuring 100% Accuracy in Antibody Protein Sequencing

The purpose of antibody protein sequencing is to accurately deduce every single amino acid present in the primary sequence. This is an issue with isoleucine and leucine which have the same molecular weight. Rapid Novor has developed a technique to determine these with 100% accuracy.

From Rapid Novor Inc 16 Apr 2019

Yeast strain provides manufacturing boost to low-calorie sweetener derived from lactose

The quest to satisfy the sweet tooth without adding to the waistline has a new weapon in its arsenal: a strain of yeast that can metabolize lactose, the sugar in dairy products, into tagatose, a natural sweetener with less than half the calories of table sugar.

16 Apr 2019

CRISPR-scanning could lead to more effective treatments for cancer

11,000 people are predicted to die from acute myeloid leukemia in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to prevent blood cells from replicating again and again and again, growing tumors.

16 Apr 2019