Biochemistry

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Newly discovered mechanism of enzyme links circadian clock and fat metabolism

The enzyme Nocturnin, which governs daily tasks such as fat metabolism and energy usage, works in an entirely different way than previously thought, reported a team of researchers at Princeton University.

30 May 2019

Artificial intelligence set to revolutionize the field of proteomics

Using artificial intelligence, researchers at the Technical University of Munich have succeeded in making the mass analysis of proteins from any organism significantly faster than before and almost error-free.

29 May 2019

Research could lead to new treatments for people with autoimmune disorders

The immune system is programmed to rid the body of biological bad guys--like viruses and dangerous bacteria--but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the system mistakes normal cells for malicious invaders, prompting the body to engage in self-destructive behavior.

29 May 2019

Lugdunin in the human nose has strong antimicrobial properties against S. aureus

Antibiotic-resistant bacteria are an increasing health threat, making new antibiotics essential. German researchers have recently had a breakthrough: they discovered lugdunin in the human nose--a new kind of cyclic peptide that comes from the bacterium Staphylococcus lugdunensis and has strong antimicrobial properties against Staphylococcus aureus, among others.

29 May 2019

Epigenetic research provides new approaches to cancer combination therapies

Epigenetic processes enable cells to respond to changes in their environment by regulating the activity of their genes.

28 May 2019

Researchers discover unexpected survival mechanism of a subset of cancer cells

Embedded at the end of chromosomes are structures called "telomeres" that in normal cells become shorter as cells divide. As the shortening progresses it triggers cell proliferation arrest or death. Cancer cells adopt different strategies to overcome this control mechanism that keeps track of the number of times that a cell has divided.

28 May 2019

Scientists discover new compound that visualizes and kills antibiotic-resistant superbugs

A new compound which visualizes and kills antibiotic-resistant superbugs has been discovered by scientists at the University of Sheffield and Rutherford Appleton Laboratory.

28 May 2019

Research into structure of anticoagulant protein may open new avenues for treatment of thrombosis

A collaboration between researchers from Brazil and the United States may open new avenues for the treatment of thrombosis, the leading cause of death among cancer patients.

27 May 2019

University of Freiburg to receive 25.8 million euros for collaborative research centers

The Deutsche Forschungsgemeinschaft has approved grant applications for two collaborative research centers at the University of Freiburg: one for continued grant funding, and one for initial grant funding.

24 May 2019

Scientist studies people with Cockayne syndrome, who don’t get cancer

Hua-Ying Fan, PhD, studies the cells of people who don't get cancer. These people have an inherited disorder called Cockayne syndrome and, unfortunately, they don't live long enough to develop cancer. But by studying their cells, Fan may be able to help them and help people with cancer, too.

24 May 2019

Genetic switch that controls conversion of bad to good fat identified

Fat cells. They are the bane of a dieter's existence, but fat is important. Previous studies showed the subcutaneous white fat cells can transform to brown and beige varieties when exposed to cold stress.

23 May 2019

Researchers decode how molecular escorts help prevent cancer

The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide.

22 May 2019

Study provides new insights into key beneficial function of small ancient protein

Cell boundaries are made of lipids. When cells are severely damaged, these lipids need to be rapidly removed to avoid toxicity and facilitate tissue healing. Researchers have discovered that a small ancient protein, Serum Amyloid A (SAA), plays a previously unknown key role in this vital process.

21 May 2019

Cutting the test time for disease biomarkers using extracellular vesicles

When an individual has cancer, or any number of other diseases, early detection can make a huge difference in the outcome. A research team led by the University of Notre Dame is working to cut the test time for disease biomarkers.

21 May 2019

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues.

21 May 2019

Researchers map molecular structure and dynamics of one of Alzheimer's stickier culprits

In a new study published in Proceedings of the National Academy of Sciences, researchers from the University of Colorado Denver and Binghamton University are the first to map the molecular structure and dynamics of an aggressive protein modification that spurs on Alzheimer's disease.

18 May 2019

Biochemistry

Newly discovered mechanism of enzyme links circadian clock and fat metabolism

Artificial intelligence set to revolutionize the field of proteomics

Research could lead to new treatments for people with autoimmune disorders

Lugdunin in the human nose has strong antimicrobial properties against S. aureus

Epigenetic research provides new approaches to cancer combination therapies

Researchers discover unexpected survival mechanism of a subset of cancer cells

Scientists discover new compound that visualizes and kills antibiotic-resistant superbugs

Research into structure of anticoagulant protein may open new avenues for treatment of thrombosis

University of Freiburg to receive 25.8 million euros for collaborative research centers

Scientist studies people with Cockayne syndrome, who don’t get cancer

Genetic switch that controls conversion of bad to good fat identified

Researchers decode how molecular escorts help prevent cancer

Study provides new insights into key beneficial function of small ancient protein

Cutting the test time for disease biomarkers using extracellular vesicles

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Researchers map molecular structure and dynamics of one of Alzheimer's stickier culprits

Marine natural compounds could be potential treatments for triple negative breast cancer

University of Virginia chemist identifies potential addiction-free pain reliever

Neurological Side Effects of CAR T-Cell Therapy Revealed

New technique for separation of cancer cells enables comprehensive genetic profiling

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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