Biochemistry

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Binding affinities of PFASs to Baikal seal PPARα revealed using in vitro and in silico approaches

A team of researchers at Ehime University revealed the binding affinities of perfluoroalkyl substances (PFASs) to Baikal seal peroxisome proliferator-activated receptor α (PPARα) using in vitro and in silico approaches.

30 Mar 2019

Designer organelles in living mammalian cells can build synthetic proteins

A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.

30 Mar 2019

Producing human protein in CHO-cells can eliminate the need for blood donors

Alpha-1-antitrypsin is a protein produced by the liver. The protein gets secreted to the blood stream, where it circulates the body to protect the lungs.

28 Mar 2019

Researchers identify crucial player in controlling misfolded proteins

Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal.

27 Mar 2019

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

The most recent developments by Wyatt in their instrumentation and software have made the full potential of FFF accessible to a wider user base. In this interview, Kim R. Williams and Christoph Johann talk to News-Medical and Life Sciences about the technologies and their research.

From Waters | Wyatt Technology 27 Mar 2019

Researchers demonstrate drug diversity in bacteria

Bacteria produce a cocktail of various bioactive natural products in order to survive in hostile environments with competing (micro)organisms.

26 Mar 2019

Antidepressant drugs may not work when neurons are out of shape

elective serotonin reuptake inhibitors are the most commonly prescribed medication for major depressive disorder, yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.

22 Mar 2019

Researchers identify genes responsible for safener efficacy in grain sorghum

Weeds often emerge at the same time as vulnerable crop seedlings and sneak between plants as crops grow. How do farmers kill them without harming the crops themselves?

22 Mar 2019

Researchers look for new ways to skirt impressive Gram-negative defense system

Superbugs, also known as Gram-negative bacteria, are causing a global health crisis. Each year in the United States, at least two million people contract an antibiotic-resistant infection, according to the Centers for Disease Control.

22 Mar 2019

Product launch from Beckman Coulter to be live streamed in March

Beckman Coulter to live stream new product launch.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 21 Mar 2019

Study finds how Salmonella bacteria sense presence of bile acids in their surroundings

When bacteria enter the digestive tracts of their hosts, including humans, they encounter a highly acidic environment.

21 Mar 2019

CRISPR/Cas libraries could revolutionize drug discovery

CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code.

20 Mar 2019

Low levels of certain eye proteins could serve as predictor for Alzheimer’s

Researchers at Boston Medical Center have found that low eye-fluid levels of two proteins associated with Alzheimer’s could serve as a potential predictor of the disease.

19 Mar 2019

Plant cellulose bone implants are “viable” option to support new bone growth, study finds

Research from the University of British Columbia and McMaster University has led to a new bone implant material made from plant cellulose. The material can be injected into bone cavities to support new growth.

19 Mar 2019

New proteomics-based test could aid in early detection of ovarian cancer

Fewer than half of ovarian cancer patients survive until five years after diagnosis. According to the American Cancer Society, this is because only about one-fifth of ovarian cancer cases are detected early, when the chances of successful treatment and recovery are highest.

15 Mar 2019