Biochemistry

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Researchers demonstrate how manganese produces parkinsonian syndrome

Using X-ray fluorescence at synchrotrons DESY and ESRF, researchers in the Centre d'Etudes Nucléaires de Bordeaux Gradignan have demonstrated the consequences of a mutation responsible for a hereditary parkinsonian syndrome: accumulated manganese in the cells appears to disturb protein transport.

16 Jan 2019

Ingenza’s Ian Fotheringham recognized with prestigious Charles Tennant Memorial Lecture award

Ingenza is proud to announce that Managing Director Ian Fotheringham has been recognized with one of SCI Scotland’s most prestigious honors – the Charles Tennant Memorial Lecture award – acknowledging his expertise and knowledge in chemical research.

16 Jan 2019

Breast cancer cells in mice coaxed to turn into harmless fat cells

As cancer cells respond to cues in their microenvironment, they can enter a highly plastic state in which they are susceptible to transdifferentiation into a different type of cell.

16 Jan 2019

Training Students to use Imaging Techniques: NMR and EPR

In this interview, Judy MacInnis from Cape Breton university, explains the importance of giving students hands-on EPR experience during in their studies.

From Bruker BioSpin - NMR, EPR and Imaging 15 Jan 2019

High Quality Purification of Proteins Through Liquid Chromatography

In this interview, AZoNetwork speaks to Knauer about the use of FPLC for purification of proteins and how their products enable scientists to get the most of liquid chromatography; conducted by Matthew Rafferty

From KNAUER Wissenschaftliche Geräte GmbH 15 Jan 2019

Plan your Pittcon 2019 with the mobile app

The Pittcon marketing department is excited to announce the release of its official conference and exposition mobile app, Pittcon 2019.

From Pittcon 14 Jan 2019

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

In a paper to be published in the September/December 2019 issue of TECHNOLOGY, a team of researchers from the Department of Biomedical Engineering at Illinois Institute of Technology, Chicago has developed a novel microfluidic device for measuring in real-time the cholesterol secreted from liver tissue-chip containing human hepatocytes.

11 Jan 2019

New generation of chemists conducts research to further understand complex nature of lipids

The post-holiday New Year might not seem like an ideal time to celebrate fat. But when it comes to lipids, there is no better time.

11 Jan 2019

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

In nature, certain molecules with the same chemical composition, can exist in two different shapes that are mirrors images of each other, much like our hands.

11 Jan 2019

Unusual molecular regulatory mechanism discovered in unicellular parasites

Researchers of the University of Bern have discovered a new molecular regulatory mechanism in unicellular parasites which has never before been observed.

10 Jan 2019

Study explains why some drugs work well in ameliorating side effects of chemotherapy

Researchers at the University of Zurich have determined the three-dimensional structure of the receptor that causes nausea and vomiting as a result of cancer chemotherapy.

10 Jan 2019

University of Cincinnati professor awarded $1.6 million NIAID grant to study Hamburger E. coli

Alison Weiss, PhD, professor in the Department of Molecular Genetics, Biochemistry and Microbiology in UC College of Medicine, has been awarded a four-year grant of $1.6 million from the National Institute of Allergy and Infectious Diseases to study Shiga toxin producing Escherichia coli 0157:H7, also sometimes referred to as Hamburger E. coli.

9 Jan 2019

Scientists fix flawed plant genes, make plants grow 40% larger

Researchers in the US have genetically engineered a way of shortcutting photosynthesis to increase the size of tobacco plants by up to 40%.

4 Jan 2019

New method for automation of DNA origami

Nature has made extravagant use of a simple molecule--DNA, the floorplan of all earthly life.

4 Jan 2019

Scientists cast new light on function of long-mysterious PCSK9 mutation

High levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading risk factor for heart disease. Many cholesterol medications lower LDL, some of them by targeting the protein PCSK9. In the January issue of the Journal of Lipid Research, scientists at the University of California, San Francisco, report on an investigation into why experiments on PCSK9 give different results in a test tube and in liver cells.

2 Jan 2019

Using Assay Kits and Dyes to Advance Cell Biology Research

In this interview, Richard Delle Bovi highlights live cell ability of the CELLESTIAL® analysis kit from Enzo Life Sciences and its applications in cell biology.

From Enzo Life Sciences, Inc. 2 Jan 2019

New research could help restore youthful characteristics

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future.

2 Jan 2019

Biologists discover how protein clumps damage cells in Parkinson's disease

Biologists studying Parkinson's disease have long hoped to solve the mystery of the telltale "clumps." Scientists want to know how clumps of misfolded proteins damage brain cells and contribute to the disease.

21 Dec 2018

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

An international team coordinated by the Interdisciplinary Research Structure in Biotechnology and Biomedicine of the University of Valencia has proved how the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to the biochemical research for decades.

19 Dec 2018

Developing the Next Generation of Water-soluble DREADDs

An interview with James Flanaghan, discussing the uses of DREADDs in neurobiological research and the advantages of water-soluble ligands.

From Hello Bio 19 Dec 2018

Biochemistry

Researchers demonstrate how manganese produces parkinsonian syndrome

Ingenza’s Ian Fotheringham recognized with prestigious Charles Tennant Memorial Lecture award

Breast cancer cells in mice coaxed to turn into harmless fat cells

Training Students to use Imaging Techniques: NMR and EPR

High Quality Purification of Proteins Through Liquid Chromatography

Plan your Pittcon 2019 with the mobile app

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

New generation of chemists conducts research to further understand complex nature of lipids

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

Unusual molecular regulatory mechanism discovered in unicellular parasites

Study explains why some drugs work well in ameliorating side effects of chemotherapy

University of Cincinnati professor awarded $1.6 million NIAID grant to study Hamburger E. coli

Scientists fix flawed plant genes, make plants grow 40% larger

New method for automation of DNA origami

Scientists cast new light on function of long-mysterious PCSK9 mutation

Using Assay Kits and Dyes to Advance Cell Biology Research

New research could help restore youthful characteristics

Biologists discover how protein clumps damage cells in Parkinson's disease

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

Developing the Next Generation of Water-soluble DREADDs

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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