Biochemistry

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Researchers succeed in building protein nanotubes from tiny scaffolds

Researchers at Tokyo Institute of Technology have succeeded in constructing protein nanotubes from tiny scaffolds made by cross-linking of engineered protein crystals.

14 Nov 2018

Salk researchers report new methods to identify AD drug candidates with anti-aging properties

Old age is the greatest risk factor for many diseases, including Alzheimer's disease (AD) and cancer. Geroprotectors are a recently identified class of anti-aging compounds.

14 Nov 2018

First bifacial molecule can invade double-stranded DNA or RNA

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a new platform for developing methods for the diagnosis and treatment of genetic conditions.

13 Nov 2018

UCI researchers accelerate and simplify directed evolution bioengineering technique

In a process known as directed evolution, scientists reengineer biomolecules to find ones that perform beneficial new functions. The field is revolutionizing drug development, chemical engineering and other applications, but to realize its promise involves painstaking and time-consuming laboratory work.

9 Nov 2018

Small molecules designed to inhibit activity of enzymes in infectious diseases

A multidisciplinary study by the Computer Biochemistry Research Group of the Universitat Jaume I from Castellón, Spain, in collaboration with groups from universities from Canada and the United Kingdom, have designed small molecules that are able to bond with and inhibit the activity of enzymes in infectious diseases.

8 Nov 2018

New nano-immunotherapy promotes long-term acceptance of transplanted organs

Researchers at the Mount Sinai School of Medicine have developed a new nanotechnology-based immunotherapy that promotes long-term transplant acceptance in an animal model.

7 Nov 2018

Researchers find cognitive changes in offspring of rats exposed to high cannabis concentrations

A study conducted by researchers at Washington State University has found changes in cognitive ability among the offspring of rats exposed to high amounts of cannabis during pregnancy.

5 Nov 2018

Molecular virologist uses basic science to fight influenza

Molecular virologist Chad Petit, Ph.D., uses basic science to fight influenza -- through experiments at the atomic level.

3 Nov 2018

Research reveals how Mycoplasma pathogens sneak past our line of defense

New research reveals that Mycoplasma pathogens make DNA in a unique way that may protect them from our immune response. The result could provide new avenues to combat the pathogens that utilize this strategy.

1 Nov 2018

New insight on quality control in the cellular immune system

Robert Tampé, Director of the Institute of Biochemistry at Goethe University, has received € 1.5 million from the German Research Foundation for a Reinhart Koselleck project.

31 Oct 2018

Researchers discover how protein pair regulates cellular calcium signals

All mammalian cells need a ready supply of calcium ions to execute functions as diverse as neurotransmission, muscle contraction, hormone release, or immune responses. So fundamental is this requirement that cells protect themselves from disaster by storing calcium in a network of intracellular cisterns called the endoplasmic reticulum, or ER.

31 Oct 2018

Texas A&M study identifies new brain region involved in inhibiting fear

A study conducted at Texas A&M University has identified a new area in the brain involved in inhibiting fear, a discovery that holds potential for clinical interventions in patients with psychiatric diseases such as post-traumatic stress disorder.

31 Oct 2018

Researchers deconstruct royal jelly that determines honeybee hierarchy

Katharina Paschinger's father, a conservation chemist in Vienna, was a devoted beekeeper. Paschinger remembers fondly that he would bring royal jelly, an important food for bee larvae, as a gift on visits to her maternal grandmother.

30 Oct 2018

Study provides a new way of thinking about cold stress in plants

When temperatures drop, plants can't bundle up. Stuck outside, exposed, plants instead undergo a series of biochemical changes that protect cells from damage.

29 Oct 2018

New method allows detection of direct biomolecule interactions

Proteins are the building blocks of the cell. They do most of the work and are essential for the structure, function and dynamic regulation of the cell and body's tissues and organs.

26 Oct 2018

Tel Aviv University researchers uncover biological ultraviolet protection 'timer'

Scientists at Tel Aviv University have discovered a critical 48-hour cycle that is responsible for synchronizing the biological mechanisms that protect our skin from sun damage.

26 Oct 2018

Kent State professor receives NIH grant to study neurological roots of fear memories

People who suffer trauma will, with few exceptions, never forget what happened to them, but a Kent State University researcher may be able to offer them the hope of living without constant fear and anxiety.

25 Oct 2018

Scientists determine normal function of gene associated with ALS and FTD

The normal function of a gene associated with the neurodegenerative diseases amyotrophic lateral sclerosis and frontotemporal dementia has been determined for the first time by University of Bath scientists.

24 Oct 2018

A major grant funds curiosity-driven research into plant communication

A major grant to fund curiosity-driven research into plant communication has been awarded to a John Innes Centre researcher and colleagues from two European institutes.

24 Oct 2018

Scientists use electron microscope to study chemical transformation in catalytic cross-coupling reaction

Scientists from Zelinsky Institute of Organic Chemistry of Russian Academy of Sciences in Moscow managed to look inside an organic chemical reaction with electron microscope and recorded the occurred transformation in real time.

23 Oct 2018