Biochemistry

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Scientists decode molecular structure of healthy huntingtin protein

Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein.

22 Feb 2018

Researchers discover new interaction mechanism of unstructured proteins

Proteins are among the most important biomolecules and are the key mediators of molecular communication between and within cells. For two proteins to be able to bind, specific regions of their three-dimensional structure have to exactly match one another - like a key that fits into a lock.

22 Feb 2018

Izon announce the launch of the qEV2 and qEV10 Exosome Isolation columns

Izon are announce the launch of two new additions to the qEV range, the qEV2 and qEV10 Exosome Isolation columns. The columns are sought after by industry professionals, and are an important feature of the popular qEV range.

From Izon Science 21 Feb 2018

Study reveals functional dynamics of ion channels

Most ion channels are very selective about the ions, which may or may not pass through them. They may be conductive for potassium ions and non-conductive for sodium ions or vice versa.

19 Feb 2018

'Click chemistry' approach may improve disease-fighting properties of drugs

Researchers at The Scripps Research Institute have developed a quick and easy way to simultaneously modify dozens of drugs or molecules to improve their disease-fighting properties.

19 Feb 2018

Resolving Interfacial Protein Dynamics by STReM

STReM stands for Super Time-Resolved Microscopy, and as STORM, PALM, and other methods are designed to improve spatial resolution of optical microscopy, we desire to improve the time resolution. STReM makes use of point spread function engineering to encode fast events into each camera frame.

From Pittcon 16 Feb 2018

Producing Super-Swelled Lyotropic Monocrystals for Drug Development

An interview with Dr. Cecília Leal, about a new method for producing bicontinuous cubic phases that are super-swollen and exist as monocrystals in solution.

15 Feb 2018

Japanese scientists synthesize water-soluble warped nanographene

Graphene and its nano-sized little sibling, nanographene, are well known for their remarkable photoelectronic properties. However, biomedical applications are hampered by the insolubility of the materials, especially in water.

12 Feb 2018

Chemist finds how to control blood sugar without usual side effects

Chemist Robert Doyle in the College of Arts and Sciences at Syracuse University has figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.

11 Feb 2018

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Production of conventional vaccines, which involves the use of live-attenuated or purified protein subunits of pathogens, is a long and complex process. Nucleic acid vaccines are safer alternatives, and allow easy adjustment of antigen to target specific pathogens.

9 Feb 2018

New family of peptides in wasp's venom may help develop better Parkinson's treatments

After being stung by a parasitic wasp, the American cockroach loses control of its behavior, becoming host to the wasp's egg.

8 Feb 2018

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule.

7 Feb 2018

UIC scientists identify new chemical compound to stop bacteria from causing sickness

A study published in the Journal of Biological Chemistry is the first to describe a signaling pathway that affects communication -- a process called quorum sensing -- between Streptococcus bacteria cells.

6 Feb 2018

Researchers shine light on ‘molecular butcher’ using neutron beams

Tucked away inside cell membranes, a molecular butcher does the bidding of healthy cells but also of disease agents. It has been operating out of clear view, but researchers just shined a mighty spotlight on it.

2 Feb 2018

Sugar-attaching enzyme found to be abundant in colon cancer cells

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry.

27 Jan 2018

Scientists use synthetic protein to disrupt bacteria’s ability to perform basic life functions

A synthetic protein that disrupts the ability of bacteria to perform basic life functions-;moving, eating, attaching to hosts-;could be a key to fighting infectious disease and preventing bacteria from evolving into drug-resistant pathogens.

27 Jan 2018

Mosquitoes can rapidly learn and remember the smell of hosts, study shows

Your grandmother's insistence that you receive more bug bites because you're 'sweeter' may not be that far-fetched after all, according to pioneering research from Virginia Tech scientists.

25 Jan 2018

New family of FFPE reagent kits launched by Beckman Coulter Life Sciences

BCLS launched a family of FormaPure reagent kits for extracting nucleic acid often-challenginging formalin-fixed, paraffin-embedded tissues.

From Beckman Coulter Life Sciences - Automation and Genomics 23 Jan 2018

Enzyme discovery provides new horizon of therapeutic opportunities across disease spectrum

Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide.

19 Jan 2018