Biochemistry

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Scientists develop new machine learning approach for synthesis, crystallization of polyoxometalates

Who is the better experimentalist, a human or a robot? When it comes to exploring synthetic and crystallization conditions for inorganic gigantic molecules, actively learning machines are clearly ahead, as demonstrated by British Scientists in an experiment with polyoxometalates published in the journal Angewandte Chemie.

4 Aug 2017

Optimizing beer’s shelf life using benchtop EPR

The main challenges in optimizing beer shelf life is that most manufacturers can only perform accelerated shelf life testing on packaged beer. So, it's almost impossible to determine where in the process you've had a positive or a negative impact on the freshness of the beer.

From Bruker BioSpin - NMR, EPR and Imaging 3 Aug 2017

Synthetic molecule can disrupt hunger-signaling pathway, research suggests

New research suggests that a man-made cousin of a small molecule found in olive oil can disrupt the hunger-signaling pathway.

27 Jul 2017

New discovery could aid in synthesis of radiotracers for use with PET scanning

Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development.

27 Jul 2017

Physicists use computer simulations to study arrangement of stiff polymers in spherical cavities

Theoretical physicists led by Professor Kurt Binder and Dr. Arash Nikoubashman at Johannes Gutenberg University Mainz in Germany have used computer simulations to study the arrangement of stiff polymers in spherical cavities.

26 Jul 2017

Nanomedical Diagnostics introduces new NTA biosensor for faster, reliable characterization of proteins

Nanomedical Diagnostics, a cutting-edge life science company pioneering graphene biosensors that accelerate pharmaceutical and biotherapeutics development, announces the launch of a new NTA biosensor chip for use with its label-free Agile R100 assay system.

26 Jul 2017

UMD scientists develop new bio-compatible ionic current-generating battery

Engineers at the University of Maryland have invented an entirely new kind of battery. It is bio-compatible because it produces the same kind of ion-based electrical energy used by humans and other living things.

24 Jul 2017

CUMC researchers capture first snapshot of key brain receptor in action

Columbia University Medical Center researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, is involved in several important brain activities, including memory and learning.

24 Jul 2017

Scientists unlock secrets of indestructible virus to create super-durable materials

It's like the Superman of viruses, astonishingly tough and able to survive in an environment that would dissolve flesh and bone. And now scientists have unlocked the secrets of its indestructibility, potentially allowing them to harness its remarkable properties to create super-durable materials and better treat disease.

19 Jul 2017

Study shows how omega-3 fatty acids can produce same medicinal qualities as marijuana

Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids.

18 Jul 2017

Research finding could pave way for novel compounds to tackle bacterial resistance

Bacteria or 'superbugs' that have adapted to resist multiple antibiotics are responsible for around 700,000 deaths globally a year; new types of antibiotics are urgently needed.

18 Jul 2017

Sartorius Stedim Biotech introduces complete range of chemistry testing services

Sartorius Stedim Biotech, a leading international supplier for the biopharmaceutical industry, announced the launch of a full range of chemistry testing services. Offered by its subsidiary Sartorius Stedim BioOutsource, they characterize the physicochemical properties and structural attributes of therapeutic monoclonal antibodies (mAbs).

From Sartorius 17 Jul 2017

Scientists gain new insights into protein network that regulates programmed cell death

Researchers use a simplified model of a protein network to explain how apoptosis is regulated, whose malfunction is linked to cancer and neurodegenerative diseases.

14 Jul 2017

Cellular antennae play key role in muscle-to-fat transformation

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such as Duchenne muscular dystrophy (DMD).

13 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

A team led by Gang Han, PhD, has designed a human protein-based, tumor-targeting Magnetic Resonance Imaging contrast that can be easily cleared by the body.

10 Jul 2017

UT Southwestern researchers develop novel chemical reaction that could accelerate drug development

Chemists have long sought to develop new reactions for the direct conversion of simple hydrocarbon building blocks into valuable materials such as pharmaceuticals in a way that dependably creates the same chemical bonds and orientations.

7 Jul 2017

Scientists shed new light on how tau protein transitions from liquid state to solid tangles

While much about Alzheimer's disease remains a mystery, scientists do know that part of the disease's progression involves a normal protein called tau, aggregating to form ropelike inclusions within brain cells that eventually strangle the neurons.

6 Jul 2017

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, and DestiNA Genomics Ltd, a manufacturer of patented reagents for nucleic acid detection, today announced that PLOS ONE has published a proof-of-concept single probe method for detecting microRNA biomarkers associated with liver toxicity.