Biochemistry

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McGill scientists invent new technique for measuring enzyme inhibition

Researchers at McGill University have invented a new technique for measuring how quickly drugs interact with their molecular targets. The discovery provides scientists with a new way to investigate the effectiveness of drug candidates that might otherwise have been overlooked.

2 Mar 2018

Study sheds light on a key protein associated with brain diseases and dementia

A new study has increased understanding of the connection between angiogenin and neurological disorders such as ALS and Fronto-temporal dementia.

1 Mar 2018

Making first responders safer with new Mira DS handheld material identification system

Metrohm is pleased to present the Mira DS, a new handheld material identification system for police, hazmat teams, bomb technicians, and military personnel.

From Metrohm USA Inc. 1 Mar 2018

Pesticides are accumulated in bodies with high fat content, FEFU scientists say

Pesticides are accumulated in bodies with high fat content. This conclusion was made by the scientists from the Far Eastern Federal University that have been studying seabirds and marine mammals of the Sea of Okhotsk and the Bering Sea for several years.

1 Mar 2018

RNA-based method cures lung tumors in mice

By turning down the activity of a specific RNA molecule researchers at Sahlgrenska Academy, Sweden, have cured lung tumors in mice by 40-50 percent.

28 Feb 2018

UGR study shows potential of cereal-based bread that curbs appetite

UGR researchers, in collaboration with the company Puratos, have conducted an in-depth study on the potential benefits of a cereal-based bread enriched with soluble fiber, proteins and dried fruit. The bread, which curbs the appetite more than traditional breads, is designed to reduce food consumption between meals and thereby control energy intake.

27 Feb 2018

Researchers develop first analytical method to evaluate new cyanide and mustard gas antidote

To develop antidotes for chemical agents, such as cyanide and mustard gas, scientists need analytical methods that track not only the level of exposure but also how the drug counteracts the effects of the chemical.

24 Feb 2018

Scientists reveal new insights into mechanism of gene regulation by 'magic spot'

Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the "magic spot"--a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

24 Feb 2018

Researchers discover mechanism that could open doors to new treatments for celiac disease

Celiac disease is an autoimmune disorder that affects by some estimates nearly 1 in 100 people. Celiac disease symptoms are triggered by gluten, a protein found in wheat and related plants, but gluten doesn't act alone to cause the digestive symptoms that patients suffer.

23 Feb 2018

UC Riverside researchers discover way to halt cancer metastasis

A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

23 Feb 2018

Desymmetrization paves way for new bioactive compounds

Many chemical molecules can exist in nature together with their mirror counterparts; like hands, two compounds can be made up of the same atoms in the same overall structure but in opposite orientations, i.e. left-handed and right-handed.

23 Feb 2018

Stiffness of cancer cell plasma membrane affects uptake of nanomedicines

Nanomedicines need to get taken up by diseased cells in order to release their cargo. Cancer cells have altered membrane properties, which hamper their ability to take up nanomedicines.

23 Feb 2018

Sartorius’ second Research Xchange Forum spotlights regenerative medicine and cell therapy

Promoting interdisciplinary exchange between science and industry on the topics of regenerative medicine and cell therapy: this is the objective Sartorius will be pursuing by hosting its second Research Xchange Forum on March 20 and 21, 2018, at Sartorius College in Goettingen.

From Sartorius 23 Feb 2018

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually suffer uncontrollable seizures. There is no cure.

22 Feb 2018

Research consortium develops first 3D computer model of metabolic processes

An international research consortium developed, with significant involvement of Luxembourg Centre for Systems Biomedicine scientists, the first computer model to include 3D in the representation of human metabolic processes.

22 Feb 2018

Scientists decode molecular structure of healthy huntingtin protein

Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein.

22 Feb 2018

Researchers discover new interaction mechanism of unstructured proteins

Proteins are among the most important biomolecules and are the key mediators of molecular communication between and within cells. For two proteins to be able to bind, specific regions of their three-dimensional structure have to exactly match one another - like a key that fits into a lock.

22 Feb 2018