Biochemistry

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High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

15 Mar 2023

New biomimetic model helps study wound healing in burn and laceration wounds

Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.

15 Mar 2023

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources.

15 Mar 2023

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Houston Methodist scientists reversed infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein, showing further evidence that links high cholesterol to female infertility.

15 Mar 2023

Women-focused diagnostics start-up wins INTEGRA Biosciences’ EVOLVE pipettes

Nanopath has been chosen as the first winner of the recently launched INTEGRA supports start-ups competition.

From INTEGRA Biosciences 15 Mar 2023

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)-;specialized molecules that can modulate RNA and alter protein production-;directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

Understanding how cells adjust in real time to withstand stresses on our health

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

Wayne State team discovers a simple technology to detect active TB infection antibodies

A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.

13 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Research illuminates the role of ATE1 enzyme in cellular stress response

A new paper in Nature Communications illuminates how a previously poorly understood enzyme works in the cell.

13 Mar 2023

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

A scientific instrument at the Department of Energy's Oak Ridge National Laboratory could help create a noninvasive cancer treatment derived from a common tropical plant.

10 Mar 2023

Natural by-product of olive oil production could support exercise

New research has found that a natural by-product of olive oil production could potentially have antioxidant benefits and support exercise.

9 Mar 2023

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

This new article publication from Acta Pharmaceutica Sinica B, discusses the development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia.

9 Mar 2023

Researchers develop a 100%-effective mRNA vaccine for deadly bacteria

For the first time in the world: a team of researchers from Tel Aviv University and the Israel Institute for Biological Research have developed an mRNA-based vaccine that is 100% effective against a type of bacteria that is lethal to humans.

9 Mar 2023

Scientists discover how excess oxygen changes a handful of proteins in the cells

When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, seizures, and even death in people and animals, particularly if it's in excess of the body's oxygen needs.

8 Mar 2023

Scientists unearth a potential new target for treating age-related neurological diseases

Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on aging processes in the brain.

8 Mar 2023

Study identifies a potential new treatment approach for acute myeloid leukemia

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells.

8 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

A shot of liver-produced hormone sobers up drunk mice

A hormone called fibroblast growth factor 21 (FGF21) protects mice against ethanol-induced loss of balance and righting reflex, according to a study publishing on March 7 in the journal Cell Metabolism.

7 Mar 2023

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer.

7 Mar 2023

Biochemistry

High consumption of common artificial sweetener lowers activation of T-cells in mice

New biomimetic model helps study wound healing in burn and laceration wounds

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Women-focused diagnostics start-up wins INTEGRA Biosciences’ EVOLVE pipettes

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

Understanding how cells adjust in real time to withstand stresses on our health

Wayne State team discovers a simple technology to detect active TB infection antibodies

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Research illuminates the role of ATE1 enzyme in cellular stress response

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

Natural by-product of olive oil production could support exercise

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

Researchers develop a 100%-effective mRNA vaccine for deadly bacteria

Scientists discover how excess oxygen changes a handful of proteins in the cells

Scientists unearth a potential new target for treating age-related neurological diseases

Study identifies a potential new treatment approach for acute myeloid leukemia

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of liver-produced hormone sobers up drunk mice

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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