Biochemistry

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Understanding Mtb's nitrogen metabolism could pave the way for more effective TB treatments

Development of new drugs to effectively target the bacterium that causes tuberculosis (TB) could be one step closer following an important discovery from the University of Surrey.

27 Mar 2023

Wild blueberries may help accelerate fat oxidation during exercise

A cup of wild blueberries a day may keep low energy at bay. The berries have long been hailed as a superfood-;while they're known for a plethora of health benefits, new research from Cal Poly Humboldt proves this superfruit could help burn fat during exercise.

27 Mar 2023

New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

More than half amount in adult human brain is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white matter.

27 Mar 2023

Antibodies produced by newly developed mRNA vaccines are transferred from pregnant rabbits to offspring

Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report March 24th in the journal Molecular Therapy.

24 Mar 2023

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value.

23 Mar 2023

Study outlines a meta-scale approach to quantifying the human proteome

A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms -; including the universally-studied worm C. elegans -; have almost the same number of genes.

23 Mar 2023

Study may pave way for a more nuanced understanding of taste perception

Humans perceive five basic taste sensations: sweet, umami, bitter, salty, and sour. Specific foods trigger taste recognition of these sensations through the activation of different receptors in our taste buds.

23 Mar 2023

Naturally-occurring compound found in trees effective in fighting superbugs

Researchers at the University of Portsmouth have discovered that a naturally-occurring compound found in trees is effective in combating superbugs.

22 Mar 2023

High-fat and high-sugar foods can rewire the brain

Chocolate bars, crisps and fries - why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future.

22 Mar 2023

Gyros Protein Technologies introduces new PurePep EasyClean services to accelerate development and manufacturing of peptide-based drugs

Gyros Protein Technologies AB today announced the launch of three service offerings to support development and manufacturing of peptide-based drugs.

From Gyros Protein Technologies AB 22 Mar 2023

AI-based design method synthesizes polymers that mimic blood plasma

Most life on Earth is based on polymers of 20 amino acids that have evolved into hundreds of thousands of different, highly specialized proteins. They catalyze reactions, form backbone and muscle and even generate movement.

20 Mar 2023

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway.

20 Mar 2023

Molecular basis for alkaline taste discovered

The sense of taste is among the first to come into contact with food before we ingest it, but whether animals can taste basic or alkaline food and how they do it remained unclear until now.

20 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

The androgen receptor is a key transcriptional factor for the proper sex development —specially in males— and the physiological balance of all the tissues that express this receptor.

17 Mar 2023

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Acute gastroenteritis afflicts adults of all ages, causing significant suffering and inflicting significant costs on the American healthcare system.

16 Mar 2023

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

16 Mar 2023

PBD Biotech’s new lyophilized PCR reaction bead offers easy ambient shipping, extends global reach of active TB test

Tuberculosis testing and treatment needs to happen close to the point of infection. PBD Biotech has developed a lyophilized PCR reaction bead for its Actiphage® blood test for active TB.

16 Mar 2023

Chemists reveal a whole new role for molecular mirroring

With the aid of some sea slugs, University of Nebraska–Lincoln chemists have discovered that one of the smallest conceivable tweaks to a biomolecule can elicit one of the grandest conceivable consequences: directing the activation of neurons.

15 Mar 2023

Biochemistry

Understanding Mtb's nitrogen metabolism could pave the way for more effective TB treatments

Wild blueberries may help accelerate fat oxidation during exercise

New technology can rapidly analyze the metabolic state of lipids in cells

Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

Antibodies produced by newly developed mRNA vaccines are transferred from pregnant rabbits to offspring

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Study outlines a meta-scale approach to quantifying the human proteome

Study may pave way for a more nuanced understanding of taste perception

Naturally-occurring compound found in trees effective in fighting superbugs

High-fat and high-sugar foods can rewire the brain

Gyros Protein Technologies introduces new PurePep EasyClean services to accelerate development and manufacturing of peptide-based drugs

AI-based design method synthesizes polymers that mimic blood plasma

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

Molecular basis for alkaline taste discovered

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

PBD Biotech’s new lyophilized PCR reaction bead offers easy ambient shipping, extends global reach of active TB test

Chemists reveal a whole new role for molecular mirroring

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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