Biochemistry

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Study solves a 50-year mystery about messenger RNAs

Messenger RNAs (mRNAs) contain chemical marks that are critical for antiviral defense in cells, according to a new study from researchers at Weill Cornell Medicine.

1 Feb 2023

Commonly prescribed antidepressants can increase bacteria's resistance to antibiotics

University of Queensland researchers have found a range of commonly prescribed antidepressants can increase bacteria's resistance to antibiotic medications.

1 Feb 2023

Cornell research provides new insight into chemotherapy agent's effect on DNA

New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish.

30 Jan 2023

$1 million grant will help University of Utah chemists to speed up the drug development process

Michael Grünwald, Ryan Looper and Rodrigo Noriega, of the University of Utah Department of Chemistry, received a $1 million grant from the W.M. Keck Foundation funding studies of currently unpredictable aspects of the process of crystallization.

30 Jan 2023

Novel mathematical model simulates how an average person's body regulates potassium

Having levels of potassium that are too high or too low can be fatal. A new mathematical model sheds light on the often mysterious ways the body regulates this important electrolyte.

30 Jan 2023

New spray can have a dual impact in the fight against antibiotic resistance

The World Health Organization ranks antibiotic resistance as one of the top ten threats to global health. There is therefore a great need for new solutions to tackle resistant bacteria and reduce the use of antibiotics.

26 Jan 2023

Researchers develop a simple new assay to eliminate heteroresistance in Enterobacter species

Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide.

24 Jan 2023

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work – until now.

23 Jan 2023

Consuming soy flour rich in protein B-conglycinin could reduce LDL cholesterol levels

A protein in soybeans blocks the production of a liver enzyme involved in the metabolism of triglycerides and low-density lipoprotein, scientists found in a recent study.

23 Jan 2023

Ingenza collaborates with Amplifica to advance novel alopecia treatments

Industrial biotech specialist Ingenza is delighted to announce that it is collaborating with clinical-stage biopharmaceutical company Amplifica Holdings Group, Inc. to develop an innovative treatment to address androgenic alopecia.

From Ingenza Ltd 23 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis.

20 Jan 2023

Researchers uncover the secret to the health benefits of brown rice

Asian diets feature rice as a staple grain, contributing towards nearly 90% of the world's rice consumption.

19 Jan 2023

Research provides a comprehensive structural framework to design safer pain-relieving drugs

In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides.

18 Jan 2023

Researchers develop long lasting surface spray with potential to kill viruses and bacteria

University of Queensland researchers have developed a long lasting surface spray that has the potential to kill viruses such as COVID-19 and potentially deadly bacteria.

17 Jan 2023

Study: Exposure to high doses of micro-sized polyethylene has adverse effects on cells

Exposure to high doses of micro-sized polyethylene has adverse effects on cells, a new study from the University of Eastern Finland finds.

17 Jan 2023

Using the power of light to transform analytical workflows in the life sciences

In this interview, we speak to Svea Cheeseman at Refeyn about their SamuxMP products used for the analysis of adeno-associated viruses (AAV) capsids.

From Refeyn 17 Jan 2023

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

A new test that 'fishes' for multiple respiratory viruses at once using single strands of DNA as 'bait', and gives highly accurate results in under an hour, has been developed by Cambridge researchers.

16 Jan 2023

Protein secreted from skeletal muscle cells and helps to repair and grow muscles

Scientists from Tokyo Metropolitan University have discovered that a protein called platelet-derived growth factor subunit B (PDGF-B) is continuously secreted from skeletal muscle cells and helps to repair muscles by encouraging myoblasts (muscle stem cells) to proliferate.

16 Jan 2023

Genetically engineering salt-resistant rice could help tackle food shortages caused by climate change

Genetically engineering rice to have better salt tolerance could allow it to be grown in places it would otherwise fail, new research from the University of Sheffield has found.

15 Jan 2023

Biochemistry

Study solves a 50-year mystery about messenger RNAs

Commonly prescribed antidepressants can increase bacteria's resistance to antibiotics

Cornell research provides new insight into chemotherapy agent's effect on DNA

$1 million grant will help University of Utah chemists to speed up the drug development process

Novel mathematical model simulates how an average person's body regulates potassium

New spray can have a dual impact in the fight against antibiotic resistance

Researchers develop a simple new assay to eliminate heteroresistance in Enterobacter species

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Consuming soy flour rich in protein B-conglycinin could reduce LDL cholesterol levels

Ingenza collaborates with Amplifica to advance novel alopecia treatments

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

Researchers uncover the secret to the health benefits of brown rice

Research provides a comprehensive structural framework to design safer pain-relieving drugs

Researchers develop long lasting surface spray with potential to kill viruses and bacteria

Study: Exposure to high doses of micro-sized polyethylene has adverse effects on cells

Using the power of light to transform analytical workflows in the life sciences

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

Protein secreted from skeletal muscle cells and helps to repair and grow muscles

Genetically engineering salt-resistant rice could help tackle food shortages caused by climate change

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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