Biochemistry

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Researchers design novel compounds with potential as drug treatments for COVID-19

The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has been devastating the entire world. While the vaccination program is advancing, drug treatments for COVID-19 are still highly important for those who become infected.

9 Dec 2022

Artificial sweetener linked to anxiety-like behavior in mice

Florida State University College of Medicine researchers have linked aspartame, an artificial sweetener found in nearly 5,000 diet foods and drinks, to anxiety-like behavior in mice.

8 Dec 2022

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

Antibodies produced against the commonly used antibiotic, gentamicin, appear to increase the risk of type 1 diabetes in children already genetically at risk, scientists say.

8 Dec 2022

Discovery of ’raspberry-shaped’ nanoparticle offers a way to enhance the effectiveness of existing drugs

A newly discovered technique, reported in the journal Nanoscale, offers a low-cost way to enhance the effectiveness of existing drugs.

7 Dec 2022

Scientists report the in vitro production of infectious Plasmodium falciparum sporozoites

Scientists from Sanaria Inc., and collaborators at multiple institutions publish results in Nature reporting "In vitro production of infectious Plasmodium falciparum sporozoites."

7 Dec 2022

Improved early detection and analysis of airborne pathogens with new liquid-coated air filters

Researchers from the University of Maine and University of Massachusetts Amherst have designed new liquid-coated air filters that allow for improved early detection and analysis of airborne bacteria and viruses, including the one that causes COVID-19.

7 Dec 2022

Paper-based synthetic biosensor could help easily detect toxin putrescine in beef

The supply chain that brings meat to market worldwide is highly complex and usually very efficient. But when disruptions in one part of the world can result in transportation delays an ocean and a continent away, meat spoilage becomes a very real risk to food producers, vendors and consumers.

6 Dec 2022

Study confirms the growing resistance in non-pathogenic Listeria species

In the food processing industry, the deadly bacteria Listeria monocytogenes is monitored closely. Not only can the bacteria make people extremely ill, it is known to be developing resistance to various food safety measures across the world.

5 Dec 2022

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases.

4 Dec 2022

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Our kidney filters 180 liters of blood every day and retains nutrients through a process called 'endocytosis' and through active transport in the kidney cells.

2 Dec 2022

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Residue from rinse agents is left behind on dishes after they are cleaned in professional-grade dishwashers.

1 Dec 2022

Using cationic nanonmaterials to target visceral adiposity

Researchers have long been working on how to treat obesity, a serious condition that can lead to hypertension, diabetes, chronic inflammation, and cardiovascular diseases.

1 Dec 2022

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.

1 Dec 2022

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

Latest research findings show that vaccine-elicited neutralizing antibodies against SARS-CoV-2 are mostly directed against one of the two main domains of the viral entry machinery.

30 Nov 2022

New urinary biomarkers could help monitor potential abuse of emerging synthetic cannabinoids

A team of scientists from the National University of Singapore (NUS) has successfully identified the urinary biomarkers of an emerging subclass of synthetic cannabinoids, called OXIZID, to monitor potential abuse.

30 Nov 2022

Bioorthogonal system for targeted release of nitrite ions into cancer cells

A team of researchers writing in the journal Angewandte Chemie has developed a bioorthogonal molecular system for the targeted introduction of nitrite ions into cells.

30 Nov 2022

Upcycling polyethylene waste into pharmacologically useful natural products

Plastic waste is one of the most significant ecological and economic problems of our time. In the journal Angewandte Chemie, a research team has now introduced a chemical–biological method for upcycling polyethylene waste: catalytic cleavage is used to make carboxylic diacids that are subsequently converted into pharmacologically useful natural products by genetically engineered fungi.

30 Nov 2022

Biochemistry

Researchers design novel compounds with potential as drug treatments for COVID-19

Artificial sweetener linked to anxiety-like behavior in mice

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

Discovery of ’raspberry-shaped’ nanoparticle offers a way to enhance the effectiveness of existing drugs

Scientists report the in vitro production of infectious Plasmodium falciparum sporozoites

Improved early detection and analysis of airborne pathogens with new liquid-coated air filters

Paper-based synthetic biosensor could help easily detect toxin putrescine in beef

Study confirms the growing resistance in non-pathogenic Listeria species

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Using cationic nanonmaterials to target visceral adiposity

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

New urinary biomarkers could help monitor potential abuse of emerging synthetic cannabinoids

Bioorthogonal system for targeted release of nitrite ions into cancer cells

Upcycling polyethylene waste into pharmacologically useful natural products

CSU engineers introduce a better way to perform mosquito-tracking for disease applications

Researchers uncovers a link between D-amino acids and severe viral infection

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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