Biochemistry

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Whole-genome sequencing is a more comprehensive prenatal test l BGI Perspectives

BGI-Research and the Maternal and Child Health Hospital of Hubei Province (MCHH) published whole-genome sequencing research results in npj Genomic Medicine.

From BGI Genomics 3 Nov 2022

Study sheds light on how Gram-negative bacteria construct outer membrane to resemble body armor

A new study published in the journal Science Advances sheds light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armor, which has far-reaching implications for the development of antibiotics.

3 Nov 2022

New method to estimate the contribution of each amino acid residue

You can't expect a pharmaceutical scientist to switch labs to the facilities available in a television studio and expect the same research output. Enzymes behave exactly the same. But now, in a study recently published in ACS Synthetic Biology, researchers from Osaka University have imparted an analogous level of adaptability to enzymes, a goal that has remained elusive for over 30 years.

3 Nov 2022

Study identifies a new therapeutic strategy to tackle endometrial cancer

Inhibition of the ERK5 protein kinase reduces the proliferation and survival of endometrial cancer cells, and potentiates standard chemotherapy.

2 Nov 2022

Molecular drug transporters could improve treatment of cancers and other diseases

A team of Canadian researchers from Université de Montréal has designed and validated a new class of drug transporters made of DNA that are 20,000 times smaller than a human hair and that could improve how cancers and other diseases are treated.

2 Nov 2022

Study finds possible treatment strategy for Feingold syndrome type 1

A decrease in protein synthesis in cells of the developing gut contributes to a rare genetic disorder, and an inexpensive nutritional supplement may help reverse that decrease, according to a new study publishing November 1st in the open access journal PLOS Biology by Yun-Fei Li of Zhejiang University School of Medicine in Hangzhou, China, and colleagues. The finding is an advance in understanding the pathogenesis of the disease, and may lead to new treatments.

2 Nov 2022

New method helps gain fundamental insights into ribosome function

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids that exit the ribosome as proteins.

1 Nov 2022

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

Many medical devices for treating heart failure generate nonphysiological shear flow. This can trigger the destruction of red blood cells after implantation of ventricular assist devices (VADs), artificial heart valves, vascular stents, or interventional thrombectomy devices.

1 Nov 2022

Researchers use AI to predict compounds that could neutralize baldness

Hair loss is undesirable for many men -; and women -; because one's hairstyle is often closely tied to their self-confidence.

31 Oct 2022

New system to detect cancer-related markers on CTCs

Having biopsies taken and endless tests run is nobody's idea of a good time, even if it's necessary for monitoring your health.

31 Oct 2022

Scientists reveal anti-inflammatory molecules that play an important role in aging

Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists reveal another factor implicated in the aging process-;a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects.

31 Oct 2022

New method to improve nanoparticle coating may enhance tumor targeting

A new technique to improve the coating of nanoparticles used in cancer therapy may enhance tumour targeting, a new study carried out in collaboration between the University of Eastern Finland and Anhui Medical University in China concludes.

31 Oct 2022

Herb may help absorb cesium from the soil around nuclear plants

A herb that grows abundantly in coastal areas can be used to rid the soil around nuclear plants of cesium, a radioactive by-product of reactors, says a new study.

31 Oct 2022

Study finds increased antioxidant activity in citrus honey

Citrus honey has an increased abundance of antioxidants in comparison to other standard types of honey, according to a new study by University of the West of Scotland (UWS).

31 Oct 2022

Ceria nanoparticles interfere with biological processes just like native enzymes

Bacteria love moist surfaces. Once they have settled there, they do not live as solitary organisms but form larger communities that are embedded in a protective film.

28 Oct 2022

Newly developed chemical compounds show promise as potential anticancer therapy

A University of Kentucky Markey Cancer Center researcher's team developed new chemical compounds that show promise as a potential anticancer therapy to treat aggressive tumors.

27 Oct 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Discovery provides better understanding of retinal protein's structure and function

Scientists have discovered a mechanism by which an area of a protein shape-shifts to convert vitamin A into a form usable by the eye's light-sensing photoreceptor cells.

26 Oct 2022

Discovery of small molecule enzyme inhibitor could be the key to treating cancers, autoimmune diseases

Researchers at the University of Illinois Chicago have found a small molecule capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases.

25 Oct 2022

Using a nanotechnology-packed bubble to detect SARS-CoV-2 virus

Scientists have shown that they can detect SARS-CoV-2, the virus that causes COVID-19, in the air by using a nanotechnology-packed bubble that spills its chemical contents like a broken piñata when encountering the virus.

25 Oct 2022

Biochemistry

Whole-genome sequencing is a more comprehensive prenatal test l BGI Perspectives

Study sheds light on how Gram-negative bacteria construct outer membrane to resemble body armor

New method to estimate the contribution of each amino acid residue

Study identifies a new therapeutic strategy to tackle endometrial cancer

Molecular drug transporters could improve treatment of cancers and other diseases

Study finds possible treatment strategy for Feingold syndrome type 1

New method helps gain fundamental insights into ribosome function

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

Researchers use AI to predict compounds that could neutralize baldness

New system to detect cancer-related markers on CTCs

Scientists reveal anti-inflammatory molecules that play an important role in aging

New method to improve nanoparticle coating may enhance tumor targeting

Herb may help absorb cesium from the soil around nuclear plants

Study finds increased antioxidant activity in citrus honey

Ceria nanoparticles interfere with biological processes just like native enzymes

Newly developed chemical compounds show promise as potential anticancer therapy

New discovery may change the textbook model of GPCR-mediated signaling

Discovery provides better understanding of retinal protein's structure and function

Discovery of small molecule enzyme inhibitor could be the key to treating cancers, autoimmune diseases

Using a nanotechnology-packed bubble to detect SARS-CoV-2 virus

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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