Biochemistry

RSS

Researchers receive grant to develop purification membranes for large-scale manufacturing of viral vectors

With a $6 million grant from the National Science Foundation, researchers at the University of Arkansas and two partner institutions will develop purification membranes for future large-scale manufacturing of viral vectors and virus-like particles.

19 Aug 2022

Researchers harness plasma-produced gas to activate plant immunity against wide-spread diseases

The flash of lightning and the dance of auroras contain a fourth state of matter known as plasma, which researchers have harnessed to produce a gas that may activate plant immunity against wide-spread diseases.

19 Aug 2022

Simple technique could be a powerful solution for disposing ‘forever chemicals’

PFAS, a group of manufactured chemicals commonly used since the 1940s, are called "forever chemicals" for a reason.

18 Aug 2022

Key gene sheds light on how people develop tolerance to pain-relievers over time

UF Scripps Biomedical Research scientists have a discovered a key gene that is shedding light on how people develop tolerance to pain-relievers over time, a problem that raises risk of addiction and overdose.

18 Aug 2022

Research suggests a new model of how beige fat biogenesis is controlled

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

17 Aug 2022

New gel-based cartilage substitute is stronger and more durable than the real thing

Over-the-counter pain relievers, physical therapy, steroid injections -- some people have tried it all and are still dealing with knee pain.

11 Aug 2022

Elevated acetate levels reprogram gut microbiota during alcohol intake

Chronic alcohol use is a major cause of liver damage and death: Approximately 30,000 persons in the United States die annually from alcoholic liver diseases, such as cirrhosis.

11 Aug 2022

Interferon beta reduces binding of three components to RBCs, study finds

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce proinflammatory molecules and even increase production of anti-inflammatory species in MS patients.

11 Aug 2022

Study quantifies the prognostic accuracy of two protein biomarkers

Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UC San Francisco, the University of Pennsylvania and the University of Michigan. Their results -- available within minutes -- may confirm the need for prompt surgical interventions or may help guide conversations with families in cases of devastating injury.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

New compound proves to be potent against more than 300 drug-resistant bacteria

Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics.

10 Aug 2022

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molecules.

9 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

Sustainable Science; What does the future look like?

We speak to Ali Safavi, CEO and Founder of Grenova about sustainable science, the impact life sciences research is having on our planet, and the solutions they offer for laboratories to help reduce their plastic waste.

From Grenova 8 Aug 2022

Locusts can differentiate between cancer cells and healthy cells, research shows

Researchers at Michigan State University have shown that locusts can not only "smell" the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines.

5 Aug 2022

New method can modify an entire substance class of medically relevant natural products

The use of the element fluorine to modify active substances is an important tool in modern drug development.

5 Aug 2022

KAIST researchers engineer a bacterial strain capable of producing lutein

A research group at KAIST has engineered a bacterial strain capable of producing lutein. The research team applied systems metabolic engineering strategies, including substrate channeling and electron channeling, to enhance the production of lutein in an engineered Escherichia coli strain.

4 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

New low-calorie sweetener could potentially have a prebiotic effect on the gut microbiome

From the wide variety of sodas, candies and baked goods that are sold worldwide, it's clear that people love their sweet treats.

4 Aug 2022

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

We are increasingly being exposed to endocrine-disrupting chemicals (EDCs) that interfere with the normal functioning of our hormones. Bisphenol A (BPA) and phthalates, which are widely used in consumer products including plastics, aluminum cans, pharmaceuticals, and cosmetics, are well-known EDCs.

4 Aug 2022

Biochemistry

Researchers receive grant to develop purification membranes for large-scale manufacturing of viral vectors

Researchers harness plasma-produced gas to activate plant immunity against wide-spread diseases

Simple technique could be a powerful solution for disposing ‘forever chemicals’

Key gene sheds light on how people develop tolerance to pain-relievers over time

Research suggests a new model of how beige fat biogenesis is controlled

New gel-based cartilage substitute is stronger and more durable than the real thing

Elevated acetate levels reprogram gut microbiota during alcohol intake

Interferon beta reduces binding of three components to RBCs, study finds

Study quantifies the prognostic accuracy of two protein biomarkers

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

New compound proves to be potent against more than 300 drug-resistant bacteria

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Researchers unravel a novel molecular target of eicosapentaenoic acid

Sustainable Science; What does the future look like?

Locusts can differentiate between cancer cells and healthy cells, research shows

New method can modify an entire substance class of medically relevant natural products

KAIST researchers engineer a bacterial strain capable of producing lutein

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

New low-calorie sweetener could potentially have a prebiotic effect on the gut microbiome

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News