Biochemistry

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Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

A team of researchers at Tohoku University has reported on a novel function of vitamin K, which is generally known for its importance in blood clotting.

4 Aug 2022

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

University of California, Irvine researchers have developed a COVID-19 test that detects and identifies specific SARS-CoV-2 variants with 100% accuracy.

3 Aug 2022

Cold exposure could make it harder for cancer cells to grow, mice study shows

Turning down the thermostat seems to make it harder for cancer cells to grow, according to a study in mice by researchers at Karolinska Institutet in Sweden.

3 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN-Bio 3 Aug 2022

Automation of established method for isolating volatile food ingredients

A research team from the Leibniz Institute for Food Systems Biology at the Technical University of Munich (LSB) has succeeded in automating an established method for the gentle, artifact-avoiding isolation of volatile food ingredients.

29 Jul 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Green methodologies for the synthesis of heterocyclic compounds

The book "Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I" is an overview of various green methodologies for the synthesis of these heterocyclic cores.

29 Jul 2022

People eating more fiber-rich food have very healthy microbiomes, study shows

That huge array of dietary fiber supplements in the drugstore or grocery aisle can be overwhelming to a consumer. They make all sorts of health claims too, not being subject to FDA review and approval. So how do you know which supplement works and would be best for you?

29 Jul 2022

Researchers report near-atomic-resolution images of nitrogenase during catalysis using cryo-EM

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action.

29 Jul 2022

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

Four billion years ago, the Earth looked very different than it does today, devoid of life and covered by a vast ocean. Over the course of millions of years, in that primordial soup, life emerged. Researchers have long theorized how molecules came together to spark this transition.

28 Jul 2022

An enzyme may be a potent new tool for reducing nitrous oxide in the atmosphere

An enzyme that combats the greenhouse gas nitrous oxide (N2O) may one day give scientists a potent new tool for reducing the amount of the gas in the atmosphere thanks in part to new findings published today in Nature.

28 Jul 2022

New method could lead to more efficient production of next-generation antibiotics

An international team of researchers has developed a method for altering one class of antibiotics, using microscopic organisms that produce these compounds naturally.

27 Jul 2022

New Zealand nettle tree toxins hold clues for future pain medication

Researchers at The University of Queensland have found that a native New Zealand stinging tree produces toxins that could hold clues for future pain medication.

27 Jul 2022

Research may have found an easy, cost-effective solution for Grapevine Trunk Diseases

Grapevine Trunk Diseases, or GTDs, are the bane of vineyard owners worldwide, and as of 2012, were responsible for more than $1.5 billion in annual economic damages.

25 Jul 2022

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently announced that they have mapped the expression and maturation of the protein alpha-1 antitrypsin (AAT) with unprecedented clarity.

25 Jul 2022

Researchers create composite layered 2D materials using biomimetic proteins

Nature creates layered materials like bone and mother-of-pearl that become less sensitive to defects as they grow.

25 Jul 2022

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

Proteins usually undergo modifications during or after their synthesis in the endoplasmic reticulum (ER) and Golgi apparatus network inside eukaryotic cells.

25 Jul 2022

Oligomeric molecular structure of the MOR-Gal1R complex revealed

A study published in the journal Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids.

22 Jul 2022

Australian researchers develop sprayable coating to shield surfaces from viruses, bacteria

A first-of-its-kind sprayable coating that can prevent the surface spread of infection from bacteria and viruses - including COVID-19 - over a sustained period –– has been developed by a team of Australian researchers.

22 Jul 2022

Researchers discover a concise way to synthesize potent natural neurotoxin

Researchers have discovered a concise way to synthesize a "biosynthetic and ecological enigma" that has intrigued chemists and biologists for more than a century: tetrodotoxin (TTX), a potent natural neurotoxin commonly associated with pufferfish that is also used as a vital probe in neuroscience research.

21 Jul 2022

Biochemistry

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

Cold exposure could make it harder for cancer cells to grow, mice study shows

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Automation of established method for isolating volatile food ingredients

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Green methodologies for the synthesis of heterocyclic compounds

People eating more fiber-rich food have very healthy microbiomes, study shows

Researchers report near-atomic-resolution images of nitrogenase during catalysis using cryo-EM

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

An enzyme may be a potent new tool for reducing nitrous oxide in the atmosphere

New method could lead to more efficient production of next-generation antibiotics

New Zealand nettle tree toxins hold clues for future pain medication

Research may have found an easy, cost-effective solution for Grapevine Trunk Diseases

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

Researchers create composite layered 2D materials using biomimetic proteins

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

Oligomeric molecular structure of the MOR-Gal1R complex revealed

Australian researchers develop sprayable coating to shield surfaces from viruses, bacteria

Researchers discover a concise way to synthesize potent natural neurotoxin

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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