Biochemistry

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Researchers explore how diet and feeding patterns affect intestinal microbes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms.

5 Jul 2022

Study opens up a new avenue for the development of selective drug therapies

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

5 Jul 2022

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.

5 Jul 2022

BICO; Combining Life Sciences Solutions to Further Human Health

As part of our SLAS Europe 2022 coverage, we speak to Héctor Martínez, CTO of BICO, about the technology and services they offer within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 5 Jul 2022

Generation of live attenuated influenza A virus vaccine using PROTAC technology

A promising strategy to reduce the impact of viral infectious diseases, such as influenza, is the use of attenuated, live viruses as vaccines.

4 Jul 2022

Two-step synthesis procedure produces amino acid Schiff base Cu (II) complexes within 10 minutes

Ever since their development in the late 19th century, Schiff bases have been a popular group of organic compounds, owing to their wide variety of desirable properties.

4 Jul 2022

Study shows the effects of "forever chemicals" on soil structure and function

Soils are impacted globally by several anthropogenic factors, including chemical pollutants. Among those, perfluoroalkyl and polyfluoroalkyl substances (PFAS) are of concern due to their high environmental persistence, which are therefore also called "forever chemicals" in public discourse.

1 Jul 2022

UTSA chemistry professor awarded NSF grant to advance research on the body's metabolic processes

Chemistry professor Aimin Liu has been awarded a three-year, $495,000 Accomplishment-Based Renewal (ABR) grant from the National Science Foundation (NSF) to advance his research on the body's metabolic processes using an innovative method that will improve the understanding of amino acids.

1 Jul 2022

Researchers fabricate highly-sensitive SERS probes to detect the PD-L1 biomarker

Recently, a team led by Prof. Huang Qing at the Institute of Intelligent Machines, Hefei Institutes of Physical Science (HFIPS) of Chinese Academy of Sciences (CAS) have reported the fabrication of ultrasensitive biosensors based on Surface-enhanced Raman Spectroscopy (SERS) to detect the cancer metastasis related programmed death ligand (PD-L1) biomarker.

1 Jul 2022

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

The experts agree -; the pandemic is not over. Infections are ticking up again, fueled by the new variants our immune systems are ill prepared for.

1 Jul 2022

Crystal structure of a human endogenous reverse transcriptase revealed

The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according to a study co-authored by a Rutgers researcher.

30 Jun 2022

Researchers discover new family of sensing genes in enteric bacteria using AI

Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence.

30 Jun 2022

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Bioaerosols, or airborne biological particles containing viruses, fungal spores, bacteria, and pollen, play a key role in public health. Antibiotic resistance (AR), caused by antibiotic resistance genes (ARGs), could potentially cause global public health crises owing to horizontal gene transfer between same or similar bacterial bioaerosols.

30 Jun 2022

The smell and sight of a meal stimulate short-lived inflammatory response in the brain

Even before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin.

30 Jun 2022

Anticancer drug candidate that targets a human protein could be a pan-viral medication

More than two years into the COVID-19 pandemic, people are realizing that the "new normal" will probably involve learning to co-exist with SARS-CoV-2. Some treatments are available, but with new variants emerging, researchers are looking toward new strategies.

29 Jun 2022

Just like magic; automated solutions for NGS library preparation

As part of our SLAS Europe 2022 coverage, we speak to Ian Shuttler from Tecan about their new MagicPrepTM NGS technology.

From Tecan 29 Jun 2022

UMass Amherst assistant professor wins $1.4 million grant to engineer synthetic bacteria for water contaminant removal

Lauren Andrews, University of Massachusetts Amherst assistant professor and the Marvin and Eva Schlanger Faculty Fellow in the department of chemical engineering, has received a three-year, $1.4 million grant from the National Science Foundation for a collaborative project to engineer synthetic bacteria to neutralize toxic contaminants found in drinking water.

28 Jun 2022

Biochemistry

Researchers explore how diet and feeding patterns affect intestinal microbes

Study opens up a new avenue for the development of selective drug therapies

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

BICO; Combining Life Sciences Solutions to Further Human Health

Generation of live attenuated influenza A virus vaccine using PROTAC technology

Two-step synthesis procedure produces amino acid Schiff base Cu (II) complexes within 10 minutes

Study shows the effects of "forever chemicals" on soil structure and function

UTSA chemistry professor awarded NSF grant to advance research on the body's metabolic processes

Researchers fabricate highly-sensitive SERS probes to detect the PD-L1 biomarker

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

Crystal structure of a human endogenous reverse transcriptase revealed

Researchers discover new family of sensing genes in enteric bacteria using AI

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

The smell and sight of a meal stimulate short-lived inflammatory response in the brain

Anticancer drug candidate that targets a human protein could be a pan-viral medication

Just like magic; automated solutions for NGS library preparation

UMass Amherst assistant professor wins $1.4 million grant to engineer synthetic bacteria for water contaminant removal

Researchers develop new chemistry on natural compounds to obtain a therapeutic agent for treating leukemia

Scientists create new fluorophores that could help fight cancer

Chemically modified rocaglates have a stronger effect against viral replication

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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