Biochemistry

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Hemp compounds show ability to prevent the entry of SARS-CoV-2 into cells

Hemp compounds identified by Oregon State University research via a chemical screening technique invented at OSU show the ability to prevent the virus that causes COVID-19 from entering human cells.

11 Jan 2022

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens.

11 Jan 2022

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Biliary atresia is a rare disease that occurs when a delicate tree-like set of ducts that carry bile from the liver to the intestine becomes scarred and blocked. While some treatments can slow the damage, most children who develop biliary atresia will die without a liver transplant.

10 Jan 2022

Mice study shows how an antimicrobial found in toothpaste can trigger gut inflammation

A new study conducted in mice demonstrates precisely how triclosan, an antimicrobial found in toothpaste, toys and thousands of other products, can trigger gut inflammation.

10 Jan 2022

Therapeutic in vivo synthetic chemistry used to make anticancer drugs

An international research group at the RIKEN Cluster for Pioneering Research (CPR) has successfully treated cancer in mice using metal catalysts that assemble anticancer drugs together inside the body.

10 Jan 2022

Common member of the gut microbiome found to have specific preference for blood group A antigens

Researchers have discovered that a common member of the human gut microbiome has a specific preference for blood group A antigens.

10 Jan 2022

Scientists discover antibody that inhibits a broad range of sarbecoviruses

Scientists have discovered an antibody that may lead to more effective treatments against a wide range of sarbecoviruses, the family of viruses that includes the coronavirus SARS-CoV-2 and their variants.

7 Jan 2022

Cryo-ET reveals molecular mechanisms underlying gene mutations within the eye

For the first time, University of California, Irvine researchers in collaboration with the Max-Planck Institute of Biochemistry, have revealed, at a molecular level, key structural determinants of the highly specialized rod outer segment (ROS) membrane architecture of the eye, which is instrumental to vision.

5 Jan 2022

Anti-fogging sprays and cloths may contain high levels of PFAS, finds study

The anti-fogging sprays and cloths many people use to prevent condensation on their eyeglasses when wearing a mask or face shield may contain high levels of per- and polyfluorinated alkyl substances (PFAS), a new Duke University-led study finds.

5 Jan 2022

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

NRL researchers aim to advance understanding of how cells organize and communicate

U.S. Naval Research Laboratory researchers in the Chemistry Division apply their knowledge of biology in conjunction with materials to improve understanding of how cells and tissues organize and apply new methods to affect cell communication.

5 Jan 2022

Computational tools reveal how blood enzyme works at the atomic level

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism.

3 Jan 2022

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Russian researchers have developed a strategy to create a cheap and rapid COVID-19 test based on isothermal amplification. According to their publication in Applied Biochemistry and Microbiology, use of this strategy will make it possible to create universal test systems for any of the COVID-19 variants.

29 Dec 2021

Introducing deuterium makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

New insights into how red meat-rich diet increases cardiovascular disease risk

A Cleveland Clinic-led study has revealed new insights into how a diet rich in red meat increases risk for cardiovascular disease. The findings were published in Nature Microbiology and build on more than a decade of research by lead author Stanley Hazen, MD, PhD.

23 Dec 2021

Eating sugar is healthy for some Greenlanders with a genetic variation

A genetic variation among some Greenlanders makes sugar healthy – significantly more than for most people.

22 Dec 2021

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5.5 million to develop new treatments for two types of devastating parasitic infections common in sub-Saharan Africa and Central and South America: river blindness and intestinal worm infections.

22 Dec 2021

Researchers discover new function of protein tBID

The protein tBID can trigger programmed cell death (apoptosis) by inducing damage in the energy suppliers of the cells, the mitochondria. Apoptosis is essential for maintaining tissue balance.

21 Dec 2021

Research reveals the structure and function of a bifunctional protein that transports heme

Heme is an essential part of the protein hemoglobin, which colors human blood red. Heme also is crucial for cytochrome proteins, which power the cell. Humans, animals, plants and bacteria all use heme.

21 Dec 2021

New study shows how regular exercise protects against fatty liver disease

Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research, Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process.

20 Dec 2021

Biochemistry

Hemp compounds show ability to prevent the entry of SARS-CoV-2 into cells

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Mice study shows how an antimicrobial found in toothpaste can trigger gut inflammation

Therapeutic in vivo synthetic chemistry used to make anticancer drugs

Common member of the gut microbiome found to have specific preference for blood group A antigens

Scientists discover antibody that inhibits a broad range of sarbecoviruses

Cryo-ET reveals molecular mechanisms underlying gene mutations within the eye

Anti-fogging sprays and cloths may contain high levels of PFAS, finds study

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

NRL researchers aim to advance understanding of how cells organize and communicate

Computational tools reveal how blood enzyme works at the atomic level

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Introducing deuterium makes drugs to have a longer effect

New insights into how red meat-rich diet increases cardiovascular disease risk

Eating sugar is healthy for some Greenlanders with a genetic variation

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Researchers discover new function of protein tBID

Research reveals the structure and function of a bifunctional protein that transports heme

New study shows how regular exercise protects against fatty liver disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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