Cell Biology

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Researchers uncover how cells invite corrupted proteins inside

Vampires can turn humans into vampires, but to enter a human's house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how cells invite inside corrupted proteins that can turn normal proteins corrupt, leading to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases.

16 Jul 2018

Research sheds on how new species may arise from rapid mitochondrial evolution

Genetic research at Oregon State University has shed new light on how isolated populations of the same species evolve toward reproductive incompatibility and thus become separate species.

13 Jul 2018

Scientists identify structural and functional differences in human immune-surveillance protein

The human body is built for survival. Each one of its cells is closely guarded by a set of immune proteins armed with nearly foolproof radars that detect foreign or damaged DNA.

13 Jul 2018

Research deepens understanding of mechanism behind organ morphogenesis

Many organs arise from simple sheets and tubes of cells. During development, these sheets bend and deform into the more complex final shape of the organ.

13 Jul 2018

Researchers develop novel approach to bridge gap in cell-free systems

Engineering cellular biology, minus the actual cell, is a growing area of interest in biotechnology and synthetic biology.

13 Jul 2018

Researchers solve protein puzzle that paves way for new cancer therapies

Researchers at Oregon State University have solved a longstanding puzzle concerning the design of molecular motors, paving the way toward new cancer therapies.

13 Jul 2018

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

In an unexpected discovery, UCLA researchers have found that a gene previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type.

13 Jul 2018

UZH scientists identify enzyme that controls cell division

When a cell divides, its constituents are usually evenly distributed among the daughter cells. UZH researchers have now identified an enzyme that guarantees that cell constituents that are concentrated in organelles without a membrane are properly distributed.

12 Jul 2018

Novel informatics tool helps predict genomic features associated with specific drug responses

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.

12 Jul 2018

Researchers discover why CRISPR gene editing sometimes fails

A study has explained for the first time why the CRISPR gene editing tool fails to work in 15% cases, and has suggested methods to prevent this.

11 Jul 2018

Researchers uncover molecular drivers of a deadly pediatric cancer

Researchers have made important discoveries about the molecular mechanisms driving acute myeloid leukemia (AML), a deadly pediatric cancer.

11 Jul 2018

Alternative splicing plays vital role in adult muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

11 Jul 2018

Cellular 'garbage disposal' may actually work on some of the proteins to neuronal development

Johns Hopkins researchers have found that the cellular "garbage disposal," known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important proteins to neuronal development.

11 Jul 2018