Cell Biology

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Acylceramides and protein-bound ceramides are vital for the formation of oral barrier in mice

Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.

12 Apr 2023

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

12 Apr 2023

Exploring the tantalizing questions about sleep

Sleep is one of the most essential human activities - so essential, in fact, that if we don't get enough sleep for even one night, we may struggle to think, react, and otherwise make it through the day.

11 Apr 2023

Key memory receptor is localized to interneurons

A key receptor regulating memory formation has been localized to interneurons, according to a study with implications for drug development.

11 Apr 2023

Novel optical imaging approach provides four-dimensional view of cell secretions

Cell secretions like proteins, antibodies, and neurotransmitters play an essential role in immune response, metabolism, and communication between cells.

11 Apr 2023

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes.

11 Apr 2023

Study expands the knowledge about gut viral diversity in healthy infants

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

11 Apr 2023

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

A study led by Mount Sinai researchers Dr. Bin Zhang, the Willard T.C. Johnson Research Professor of Neurogenetics, and Dr. Christian Forst, an Associate Professor in the Department of Genetics and Genomic Sciences, have identified potential novel receptors for SARS-CoV-2 and unveiled their tissue-specific and age-dependent expression.

11 Apr 2023

Isolating tumor-reactive blood cells to treat cancers

Adoptive cell therapy (ACT) has become a promising immunotherapy tool to help treat advanced melanoma.

10 Apr 2023

Beclin-1 plays a key role in endometrial reprogramming for successful establishment of pregnancy

Throughout a woman's reproductive life, the endometrium, the mucous membrane lining the uterus, goes through cyclical remodeling. It thickens during the menstrual cycle in preparation for embryo implantation, and it is shed during menstruation when there is no fertilization.

10 Apr 2023

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

10 Apr 2023

New finding in roundworms upends classical thinking about animal cell differentiation

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

7 Apr 2023

Regulatory T cell populations descend from two different origins, finds study

A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's Hospital of Philadelphia (CHOP).

7 Apr 2023

Leveraging cell self-destruction to treat glioblastoma tumors

Glioblastoma is the most common type of brain tumor in adults. The disease is 100% fatal and there are no cures, making it the most aggressive type of cancer. Such a poor prognosis has motivated researchers and neurosurgeons to understand the biology of tumors with the goal of creating better therapies.

7 Apr 2023

Highly complementary, biologically relevant protein-protein interactions can evolve entirely by chance

Proteins are the key players for virtually all molecular processes within the cell. To fulfil their diverse functions, they have to interact with other proteins.

7 Apr 2023

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Researchers at the University of Washington School of Medicine in Seattle have engineered stem cells that do not generate dangerous arrhythmias, a complication that has to date thwarted efforts to develop stem-cell therapies for injured hearts.

7 Apr 2023

Study suggests new strategy to ward off age-related weight gain

New research suggests a strategy to ward off age-related weight gain, which could prevent obesity and associated health disorders like Type 2 diabetes, heart disease and chronic inflammation.

7 Apr 2023

Ingenious device enables construction of complex 3D organoids in a simpler way

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques.

7 Apr 2023

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study.

6 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

Cell Biology

Acylceramides and protein-bound ceramides are vital for the formation of oral barrier in mice

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Exploring the tantalizing questions about sleep

Key memory receptor is localized to interneurons

Novel optical imaging approach provides four-dimensional view of cell secretions

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Study expands the knowledge about gut viral diversity in healthy infants

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

Isolating tumor-reactive blood cells to treat cancers

Beclin-1 plays a key role in endometrial reprogramming for successful establishment of pregnancy

Using the gene-editing tool to model certain liver tumor subtypes

New finding in roundworms upends classical thinking about animal cell differentiation

Regulatory T cell populations descend from two different origins, finds study

Leveraging cell self-destruction to treat glioblastoma tumors

Highly complementary, biologically relevant protein-protein interactions can evolve entirely by chance

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Study suggests new strategy to ward off age-related weight gain

Ingenious device enables construction of complex 3D organoids in a simpler way

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

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