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New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

A new study discusses the development of an improved protocol based on cell lines that can consistently express S proteins.

5 Aug 2021

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

A new study has revealed the mechanism by which the SARS-CoV-2 N protein activates NLRP3 inflammasomes to induce hyperinflammation.

5 Aug 2021

New longevity metric: Average human lifespan reduced drastically by COVID-19

At its peak, COVID-19 drastically reduced the average human lifespan — by as much as 9 years in one U.S. state — according to a new longevity metric developed at UCLA.

5 Aug 2021

Zoonotic disease surveillance must be integrated into health security intelligence systems, experts say

The surveillance of zoonotic diseases must be integrated into health security intelligence systems, if future pandemics are to be handled effectively, according to global health practitioners writing in the Journal of the Royal Society of Medicine.

5 Aug 2021

COVID vaccines generate antibodies in saliva

Researchers in the United States and Canada have conducted a study showing that the vaccines developed by Pfizer-BioNTech and Moderna to protect against coronavirus disease 2019 (COVID-19) generate local antibody responses in the salivary gland that are independent of the systemic immune response.

5 Aug 2021

Vaccination may protect against SARS-CoV-2 infection at the eye surface

Researchers in Australia have conducted a study showing that vaccination against coronavirus disease 2019 (COVID-19) induces key antibodies at the eye surface that may help to protect against the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Aug 2021

Study demonstrates the potency of herbal medicines against Bartonella henselae

Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the U.S., today announced the publication of new data showing that herbal medicines have potent activity in test tubes compared to pharmaceuticals commonly-prescribed for the treatment of Bartonella henselae, a bacterium believed to be carried by ticks and the cause of cat scratch fever.

5 Aug 2021

COVID-19 vaccination offers significant protection for solid organ transplant recipients

In a Brief Communication, published July 29, 2021 in the journal Transplant Infectious Disease, a team of physician-scientists at University of California San Diego School of Medicine found that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.

5 Aug 2021

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

In an article in the New England Journal of Medicine, scientists from Fred Hutchinson Cancer Research Center, Johns Hopkins Bloomberg School of Medicine, the U.S. Military HIV Research Program and the Institute for Global Health and Infectious Diseases at the University of North Carolina urged increased attention to persistent COVID-19 infections in immunocompromised people.

5 Aug 2021

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Researchers remain perplexed as to why some patients infected with SARS-CoV-2, the virus responsible for COVID-19, remain asymptomatic while other patients develop severe disease symptoms.

5 Aug 2021

Nine things parents should know about the Delta variant to keep children safe as schools reopen

Despite the rise in Delta variant cases, increased hospitalizations and reinstated mask mandates, many schools are set to reopen as early as next week.

5 Aug 2021

KHN’s ‘What the Health?’: Delta blues

The U.S. is experiencing another surge of covid-19, particularly in Southern states where vaccination rates are generally lower than in other regions. But partisan fights rage on over what role government should play in trying to tamp down the highly contagious delta variant.

5 Aug 2021

A correlation study between time-from-vaccine and SARS-CoV-2 breakthrough infections

A new retrospective study compares the incidence rates of breakthrough infections between different time points at which individuals were vaccinated.

5 Aug 2021

Invasive 'famine weed' could escalate the spread of malaria

An invasive weed could escalate the spread of malaria in East Africa after scientists found new evidence that it creates a favourable breeding ground for female mosquitoes, which transmit malaria.

5 Aug 2021

Vaccinia-based COVID-19 vaccines confer immunity in hamster model

In a paper recently uploaded to the preprint server bioRxiv* by Kulkarni et al. (August 3, 2021), the potential of vaccinia virus-based vaccines expressing the full-length SARS-CoV-2 spike protein is examined in mice and Syrian hamsters. The findings report that the vaccine generates high titers of neutralizing antibodies with good activity towards SARS-CoV-2 variants of concern.

5 Aug 2021

New study examines B cell receptor repertoires in COVID-19 patients

In a paper recently uploaded to the preprint server bioRxiv* by Kim et al. (August 2, 2021), the B cell receptor repertoire of 1,060 COVID-19 patients is compared to that of an equal number of healthy volunteers in a novel manner, utilizing computational deep-learning-based protein embedding techniques, which demonstrate a resolution capable of tracking the changes in immunity in an individual over the course of infection.

5 Aug 2021

Immunocompromised patients could be potential hosts for immune-escape mutants of SARS-CoV-2

In a recently published article in The New England Journal of Medicine, scientists have described how multi-mutational variants of SARS-CoV-2 may evolve in patients with immunosuppression.

5 Aug 2021

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Modified mRNA combined with lipid nanoparticles may be beneficial in boosting adaptive immunity against SARS-CoV-2. Research led by Botond Z. Igyártó from Thomas Jefferson University’s Department of Microbiology and Immunology in Pennsylvania recently found that the lipid nanoparticles induce protective adaptive immune responses with antibody titers against lethal doses of the virus.

5 Aug 2021

Could a plant metabolite in liverworts be a potent antiviral against SARS-CoV-2 and other RNA viruses?

A new study from the National Centre for Biotechnology and Medicinal Chemistry Institute suggests Mother Nature delivered — in the form of liverworts. They found that the bryophyte Marchantia polymorpha, also known as umbrella liverworts, could work as a potential antiviral treatment.

5 Aug 2021

Post-COVID-19 neurological sequalae are not due to brain injury, study shows

In a recent study from University of Gothenburg, it has been shown that all participants achieve normalization of CNS injury biomarkers, regardless of previous disease severity or persistent neurological symptoms. Indicating that post-COVID-19 neurological sequalae are not due to active brain injury.

5 Aug 2021

Disease/Infection News

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

New longevity metric: Average human lifespan reduced drastically by COVID-19

Zoonotic disease surveillance must be integrated into health security intelligence systems, experts say

COVID vaccines generate antibodies in saliva

Vaccination may protect against SARS-CoV-2 infection at the eye surface

Study demonstrates the potency of herbal medicines against Bartonella henselae

COVID-19 vaccination offers significant protection for solid organ transplant recipients

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Nine things parents should know about the Delta variant to keep children safe as schools reopen

KHN’s ‘What the Health?’: Delta blues

A correlation study between time-from-vaccine and SARS-CoV-2 breakthrough infections

Invasive 'famine weed' could escalate the spread of malaria

Vaccinia-based COVID-19 vaccines confer immunity in hamster model

New study examines B cell receptor repertoires in COVID-19 patients

Immunocompromised patients could be potential hosts for immune-escape mutants of SARS-CoV-2

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Could a plant metabolite in liverworts be a potent antiviral against SARS-CoV-2 and other RNA viruses?

Post-COVID-19 neurological sequalae are not due to brain injury, study shows

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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