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Research uncovers an unexpected role for immune T cells in protection against malaria

Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.

23 Jul 2021

Advantages and challenges of intranasal vaccines to fight against COVID-19 infections

There are many reasons that an intranasal vaccine against the SARS-CoV-2 virus would be helpful in the fight against COVID-19 infections, University of Alabama at Birmingham immunologists Fran Lund, Ph.D., and Troy Randall, Ph.D., write in a viewpoint article in the journal Science.

23 Jul 2021

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

The body's first encounter with SARS-CoV-2, the virus behind COVID-19, happens in the nose and throat, or nasopharynx. A new study in the journal Cell suggests that the first responses in this battleground help determine who will develop severe disease and who will get through with mild or no illness.

23 Jul 2021

Researchers discover camelid-derived two nanobodies that target SARS-CoV-2

A new study has been published on the bioRxiv* preprint server, which has identified and characterized two RBD-targeting neutralizing nanobodies, namely, DL4 and DL28.

23 Jul 2021

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

A new study has been published on the bioRxiv* preprint server, which has used MS to identify T cell epitopes of SARS-CoV-2 conserved protein, i.e., the membrane glycol protein (MGP) and the non-structure protein-13 (NSP13).

23 Jul 2021

SARS-COV-2 infection leads to neutralizing and protective serological responses in over 70% of DPs

Iain Chapple, University of Birmingham, England, presented the oral session "Longitudinal Serological and Vaccination Responses to SARS-COV-2 in Dental Professionals" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.

23 Jul 2021

CDC monitoring over 200 individuals possibly exposed to monkeypox

The United States Centers for Disease Control and Prevention (CDC) is monitoring over 200 people who may have been exposed to the monkeypox virus.

22 Jul 2021

First dose of Pfizer-BioNTech or Oxford-AstraZeneca vaccines has strong protective effect against COVID-19 in older adults

A new study estimates vaccine effectiveness against COVID-19 mortality in England using the RDD approach.

22 Jul 2021

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

A new study characterizes the functional humoral immunity post-COVID-19 mRNA-based vaccination.

22 Jul 2021

Study reveals potential long-term effects of malnutrition on COVID-19 outcomes

Adults and children with COVID-19 who have a history of malnutrition may have an increased likelihood of death and the need for mechanical ventilation, according to a study published in Scientific Reports.

22 Jul 2021

Synergistic multi-antibody cocktail protects against SARS-CoV-2 in animal model

Researchers in Canada have reported the discovery of a multi-antibody cocktail that synergistically protected against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an animal model of acute infection.

22 Jul 2021

Study highlights the burden of oral diseases in emerging countries

Jiachen Lin, Harvard School of Dental Medicine, Boston, Mass., USA., presented the poster "Burden of Oral Diseases in Emerging Countries: A Prediction Model" at the virtual 99th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 50th Annual Meeting of the American Association for Dental Research and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.

22 Jul 2021

KHN’s ‘What the Health?’: Delta changes the covid conversation

The resurgence of covid cases in the U.S. — largely attributable to the much more contagious delta variant — has given policymakers the jitters.

22 Jul 2021

Study in France suggests high efficacy of mRNA vaccines against SARS-CoV-2 variants of concern

A nationwide case-control study conducted in France has assessed the efficacy of mRNA-based coronavirus disease 2019 (COVID-19) vaccines against original severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants, including B.1.1.7, B.1.351, and P1.

22 Jul 2021

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

A recent study conducted at the University of Texas Science Center, Houston, in the USA, has revealed that upon infection, SARS-CoV-2 alters the host chromatin architecture to suppress antiviral interferon-responsive genes and augment inflammatory genes. The study is currently available on the bioRxiv* preprint server.

22 Jul 2021

Can platelet size predict severity and mortality in COVID-19?

The ongoing COVID-19 pandemic has baffled researchers with its propensity to cause symptoms of largely unpredictable severity in the affected individuals. An exciting new study reports on the potential predictive value of platelet size in this situation. COVID-19 patients with severe disease often develop clots in vital organs, which leads to further complications. It is known that platelet size is a good indicator of activation.

22 Jul 2021

Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

A new study, recently released as a preprint on the medRxiv* server, reports the intriguing finding that the cross-neutralizing antibodies elicited by human seasonal coronaviruses (sCoVs) show varying ability to prevent binding between the SARS-CoV-2 spike antigen and its cognate receptor, the angiotensin-converting enzyme 2 (ACE2).

22 Jul 2021

Pfizer vaccine and isolation independently associated with reduced household transmission of SARS-CoV-2

Israel was among the leading proponents of COVID-19 vaccination as the way out of the current worldwide restrictions on social and economic interactions and activity. A new study, recently released as a preprint on the medRxiv* server, reports on the effects of the large-scale vaccination campaigns carried out in this country, relating to successful control of SARS-CoV-2 spread within households.

22 Jul 2021

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Research led by Queen Mary University of London provides new insight into the mechanisms that lead to uncontrolled inflammation in COVID-19 patients.

22 Jul 2021

Epstein-Barr virus reactivation may play a role in long COVID and severe COVID-19 cases

Two recently published studies available on the National Institutes of Health website indicate Epstein-Barr virus (EBV) reactivation may play a role both in the development of long COVID symptoms, as well as severe COVID-19 cases.

22 Jul 2021

Disease/Infection News

Research uncovers an unexpected role for immune T cells in protection against malaria

Advantages and challenges of intranasal vaccines to fight against COVID-19 infections

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

Researchers discover camelid-derived two nanobodies that target SARS-CoV-2

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

SARS-COV-2 infection leads to neutralizing and protective serological responses in over 70% of DPs

CDC monitoring over 200 individuals possibly exposed to monkeypox

First dose of Pfizer-BioNTech or Oxford-AstraZeneca vaccines has strong protective effect against COVID-19 in older adults

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

Study reveals potential long-term effects of malnutrition on COVID-19 outcomes

Synergistic multi-antibody cocktail protects against SARS-CoV-2 in animal model

Study highlights the burden of oral diseases in emerging countries

KHN’s ‘What the Health?’: Delta changes the covid conversation

Study in France suggests high efficacy of mRNA vaccines against SARS-CoV-2 variants of concern

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

Can platelet size predict severity and mortality in COVID-19?

Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

Pfizer vaccine and isolation independently associated with reduced household transmission of SARS-CoV-2

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Epstein-Barr virus reactivation may play a role in long COVID and severe COVID-19 cases

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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