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High throughput screening for COVID-19 with the VOYAGER pipette

The COVID-19 pandemic has slowed down research in many scientific areas, but for the Jain Lab in the Department of Chemical Engineering at the University of Florida, the pandemic has created an exciting opportunity to repurpose their work.

From INTEGRA Biosciences 24 Mar 2021

Delays in TB diagnosis often exceed WHO’s recommendations, shows study

Tuberculosis remains a rare disease in the United States, but when it does occur, delays in diagnosing it often exceed recommendations by the World Health Organization, according to a new report by Harvard Medical School researchers published March 22 in The Lancet Infectious Diseases.

24 Mar 2021

Survey of surge capacity managers captures pandemic preparedness status of the U.S. health care system

A University of Pittsburgh School of Medicine-led survey of dozens of surge capacity managers at hospitals nationwide captures the U.S. health care system's pandemic preparedness status in the months before the first COVID-19 cases were identified in China.

24 Mar 2021

Delaying second doses of COVID-19 vaccines can reduce positive cases

Delaying second doses of COVID-19 vaccines should reduce case numbers in the near term; however, the longer term case burden and the potential for evolution of viral ‘escape’ from immunity will depend on the robustness of immune responses generated by natural infections and one or two vaccine doses, according to a study from McGill University and Princeton University published today in Science.

24 Mar 2021

Epitope antibody testing is effective in detecting immune responses to SARS-CoV-2

A new preprint study led by Shawn S-C. Li from Western University in Ontario, Canada, provides evidence of epitope-specific antibody responses and designed a test to measure this in relation to disease severity and outcome after infection.

24 Mar 2021

New range of lung-on-chip technologies represent the vital properties of lung tissue

According to the National Institutes of Health, respiratory viruses are the most frequent cause of disease and death in humans, a fact highlighted by the COVID-19 pandemic. Despite the potential to cause severe disease, over 70% of viral infections remain asymptomatic.

24 Mar 2021

Study shows how surveillance-based informative testing mitigates COVID-19 spread

While COVID-19 cases may be on the decline, the virus is still prevalent nationwide, and higher education institutions need to prepare for a successful 2021 academic year.

24 Mar 2021

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients.

24 Mar 2021

Rapid antigen testing helps decrease the prevalence of SARS-CoV-2 in Slovakia

In Slovakia, in counties subject to two rounds of rapid antigen testing for SARS-CoV-2 where those who tested positive then isolated, the approach helped decrease the prevalence of positive tests by more than 50% in a week - all while primary schools and workplaces remained open.

24 Mar 2021

Research suggests toothpaste and mouthwash ingredients could help prevent SARS-CoV-2 infection

Now, new research published on the bioRxiv preprint server focuses on the effect of some typical ingredients present in commercially available mouthwashes and toothpaste on the mechanisms of SARS-CoV-2 entry into host cells.

24 Mar 2021

Vaccination of health care workers resulted in notable reduction of COVID-19 cases

Vaccinating health care workers resulted in an immediate and notable reduction of positive COVID-19 cases among employees, reducing the number of required isolations and quarantines by more than 90 percent, according to data at UT Southwestern Medical Center published in the New England Journal of Medicine.

24 Mar 2021

Glycans play a key role in COVID-19 infection, shows study

A research group at the RIKEN Center for Computational Science (R-CCS) has found that glycans—sugar molecules—play an important role in the structural changes that take place when the virus which causes COVID-19 invades human cells.

24 Mar 2021

SARS-CoV-2 infection after vaccination is possible, shows study

In a letter to The New England Journal of Medicine, published online March 23, 2021, a group of investigators from University of California San Diego School of Medicine and the David Geffen School of Medicine at UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus.

24 Mar 2021

Pandemic fear is killing patients suffering from other serious diseases

During the COVID-19 pandemic, Joseph S. Alpert, MD, Editor-in-Chief of The American Journal of Medicine, published by Elsevier, has observed that although non-COVID inpatients suffered from the usual mix of conditions such as heart failure and chronic obstructive pulmonary disease exacerbations, the Internal Medicine inpatient population was distinctly different from what he had seen over the past decades.

24 Mar 2021

New guidance can help identify communities at highest risk of tuberculosis

An estimated 1.4 million fewer people received care for tuberculosis (TB) in 2020 than in 2019, according to preliminary data compiled by the World Health Organization (WHO) from over 80 countries- a reduction of 21% from 2019.

24 Mar 2021

Potent nanobody binds SARS-CoV-2 spike in an extraordinary manner

In a new study, published recently on the bioRxiv preprint server, researchers isolated a nanobody that potently neutralizes SARS-CoV-2, including the B.1.351 variant, and cross-neutralizes SARS-CoV. They demonstrated the therapeutic potential of the nanobody in a human ACE2 (angiotensin-converting enzyme) transgenic mouse model.

24 Mar 2021

People who received flu shot last season had fewer complication of COVID-19

People who received a flu shot last flu season were significantly less likely to test positive for a COVID-19 infection when the pandemic hit, according to a new study.

23 Mar 2021

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

The CVnCoV mRNA vaccine showed neutralizing antibody levels and completely protected mice infected with the B.1.351 variant. No viral genomes were seen in oral swabs, lungs, or brain.

23 Mar 2021

Pilot study finds Bartonella infection in the blood of people with schizophrenia

A pilot study from North Carolina State University and the University of North Carolina at Chapel Hill has found evidence of Bartonella infection in the blood of people with schizophrenia and schizoaffective disorder.

23 Mar 2021

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Previous research identified the interferon-responsive OAS1 gene as a risk gene for Alzheimer's disease. OAS1 is an enzyme that binds to double-stranded RNA and induces the conformation to create oligoadenylates. They also activate RNase L to break down RNA.

23 Mar 2021

Disease/Infection News

High throughput screening for COVID-19 with the VOYAGER pipette

Delays in TB diagnosis often exceed WHO’s recommendations, shows study

Survey of surge capacity managers captures pandemic preparedness status of the U.S. health care system

Delaying second doses of COVID-19 vaccines can reduce positive cases

Epitope antibody testing is effective in detecting immune responses to SARS-CoV-2

New range of lung-on-chip technologies represent the vital properties of lung tissue

Study shows how surveillance-based informative testing mitigates COVID-19 spread

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Rapid antigen testing helps decrease the prevalence of SARS-CoV-2 in Slovakia

Research suggests toothpaste and mouthwash ingredients could help prevent SARS-CoV-2 infection

Vaccination of health care workers resulted in notable reduction of COVID-19 cases

Glycans play a key role in COVID-19 infection, shows study

SARS-CoV-2 infection after vaccination is possible, shows study

Pandemic fear is killing patients suffering from other serious diseases

New guidance can help identify communities at highest risk of tuberculosis

Potent nanobody binds SARS-CoV-2 spike in an extraordinary manner

People who received flu shot last season had fewer complication of COVID-19

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

Pilot study finds Bartonella infection in the blood of people with schizophrenia

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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