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Researchers track movements and symptoms during COVID-19 pandemic

New George Mason University College of Health and Human Services study is one of the first individual-level studies to track movements and symptoms during the COVID-19 pandemic.

26 Mar 2021

Genomic sieve analysis can inform the development of SARS-Cov-2 vaccine

As concern has grown over COVID-19 variants and their implications for how well COVID-19 vaccines will protect against the virus, researchers have proposed a method to examine instances of SARS-COV-2 infections in people who have received a COVID-19 vaccine.

26 Mar 2021

Study: COVID-19 vaccines may remain effective against new influenza viruses

Influenza vaccines need to be evaluated every year to ensure they remain effective against new influenza viruses.

26 Mar 2021

DNMT3a plays a key role in regulating HSC responses to infections

Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections.

26 Mar 2021

Antibody used for COVID-19 therapy does not inhibit SARS-Cov-2 variants

Cell culture studies show that mutated viruses are less susceptible to inhibition by antibodies from recovered or vaccinated individuals.

26 Mar 2021

First-of-its-kind project to disseminate bundled interventions for Black women with HIV

The University of Massachusetts Lowell, in collaboration with AIDS United, and the Center for Innovation in Social Work & Health at Boston University's School of Social Work (BUSSW), have been tapped to lead a national, first-of-its-kind project to evaluate and disseminate bundled evidence-informed and trauma-informed interventions for Black women with HIV.

25 Mar 2021

Vaccine hesitancy could pose a major threat to public health efforts to end COVID-19

Although demand for COVID-19 vaccines currently seems high, vaccine hesitancy could pose a major threat to public health efforts to end the pandemic, according to an editorial published today in the journal Science.

25 Mar 2021

Study shows substantial benefit of combination therapy for advanced Marburg infections

A new study conducted at the Galveston National Laboratory at the The University of Texas Medical Branch at Galveston has shown substantial benefit to combining monoclonal antibodies and the antiviral remdesivir against advanced Marburg virus.

25 Mar 2021

Drugging RNA synthesis in SARS-CoV-2 as novel therapeutic avenue

In a new study, the role of a coronavirus-specific protein domain in SARS-CoV-2 viral synthesis initiation is investigated, and potential therapeutic solutions have been explored.

25 Mar 2021

Study observes correlation between COVID-19 mortality and autoantibodies in corticosteroid treated patients

Corticosteroid anti-inflammatory drugs have been applied to COVID-19 patients over the course of the pandemic, though the results are mixed. In a recent study, the outcomes for such patients are collated, demonstrating a striking correlation between the development of autoantibodies and mortality.

25 Mar 2021

Identification of specific anti-SARS-CoV-2 antibodies with cross-neutralization potency

A team of scientists from the USA and Canada recently characterized the cross-neutralizing potency of anti-SARS-CoV-2 antibodies isolated from COVID-19 patients. The findings reveal that some of the isolated antibodies targeting the spike RBD and the S2 subunit are capable of cross-neutralizing other members of the human beta-coronavirus family.

25 Mar 2021

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

The scientific consensus is that safe and highly effective vaccines are required to end the ongoing pandemic of coronavirus disease 2019 COVID-19, caused by SARS-CoV-2. A new study describes a new vaccine that presents two viral antigens to the human immune system, in order to elicit a more efficacious response.

25 Mar 2021

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

A new study, which was released on the bioRxiv* preprint server, shows the differential effect that a standard vaccine protocol may have on individuals, based on their history of prior infection with the virus.

25 Mar 2021

Could dry swabs provide cheaper, safer and faster material for SARS-CoV-2 testing?

A new study deals with the feasibility of using dry swab samples to isolate the virus, as compared to wet swabs, to reduce costs while improving safety.

25 Mar 2021

Researchers find evidence that SARS-CoV-2 infects cells in the mouth

An international team of scientists has found evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth.

25 Mar 2021

Researchers examine SARS-CoV-2 RNA interactome

A new study focuses on the identification of RNA-binding protein by mass spectrometry (ChIRP-M/S) approach. This study develops a global map that contains the complete set of host proteins that involve the SARS-CoV-2 genome during infection. This study has successfully identified new SARS-CoV-2 host dependency factors by merging proteomics data with gene silencing experiments. Such a discovery has paved new roads to develop more antiviral therapies.

25 Mar 2021

World-first treatment for oral cancer

Professor Mark McGurk speaks to News-Medical about his groundbreaking research that has led to the discovery of a world-first treatment for oral cancer.

25 Mar 2021

COVID vaccines have only 17% detectable antibodies against SARS-CoV-2 virus

When clinical trials were conducted to determine the immunogenicity -- the ability to elicit an immune response -- for the first two vaccines marshaled against SARS-CoV-2the virus that causes COVID-19, one group was not among those included: people who have received solid organ transplants and others (such as those with autoimmune disorders) who are immunocompromised.

25 Mar 2021

Shame and stigmatization of contracting COVID-19 are linked to lower compliance of social distancing

New research from the University of Kent and Leeds Beckett University has found that feelings of shame and stigmatization at the idea of contracting Covid-19 are linked to lower compliance of social distancing and the likelihood of reporting infection to authorities and potential contacts in Italy, South Korea, and the USA.

25 Mar 2021

Changing upper respiratory microbiome in children related to SARS-CoV-2 susceptibility

Researchers tested the nasopharyngeal microbiome of children up to 21 years old and found the microbiome changes with age. Specific bacteria, whose abundance also changes with age, are associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection susceptibility and severity.

25 Mar 2021

Disease/Infection News

Researchers track movements and symptoms during COVID-19 pandemic

Genomic sieve analysis can inform the development of SARS-Cov-2 vaccine

Study: COVID-19 vaccines may remain effective against new influenza viruses

DNMT3a plays a key role in regulating HSC responses to infections

Antibody used for COVID-19 therapy does not inhibit SARS-Cov-2 variants

First-of-its-kind project to disseminate bundled interventions for Black women with HIV

Vaccine hesitancy could pose a major threat to public health efforts to end COVID-19

Study shows substantial benefit of combination therapy for advanced Marburg infections

Drugging RNA synthesis in SARS-CoV-2 as novel therapeutic avenue

Study observes correlation between COVID-19 mortality and autoantibodies in corticosteroid treated patients

Identification of specific anti-SARS-CoV-2 antibodies with cross-neutralization potency

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

Could dry swabs provide cheaper, safer and faster material for SARS-CoV-2 testing?

Researchers find evidence that SARS-CoV-2 infects cells in the mouth

Researchers examine SARS-CoV-2 RNA interactome

World-first treatment for oral cancer

COVID vaccines have only 17% detectable antibodies against SARS-CoV-2 virus

Shame and stigmatization of contracting COVID-19 are linked to lower compliance of social distancing

Changing upper respiratory microbiome in children related to SARS-CoV-2 susceptibility

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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