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Simple pooled testing method can be an effective tool for curbing COVID-19 pandemic

A new approach to pooled COVID-19 testing can be a highly effective tool for curbing the SARS-CoV-2 pandemic, even if infections are widespread in a community, according to researchers at Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.

25 Feb 2021

Extensive use of opioid agonists can considerably reduce drug-related deaths

New evidence that opioid agonists such as methadone and buprenorphine could substantially reduce drug-related deaths if more widely used in the community and prison, and for longer, has been published in Lancet Psychiatry.

25 Feb 2021

Antibody and T cell response to SARS-CoV-2 persist up to 8 months: Study of Ski Resort Ischgl

The first instance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Austria was observed in the Ski resort Ischgl in early March 2020. Later, the virus spread across Austria and other countries in Northern Europe.

25 Feb 2021

Pre-existing cross-reactive HCoV antibodies could protect against SARS-CoV-2

A team of researchers from Spain and Canada recently characterized the antibody kinetics and neutralization capacity at 4 cross-sectional surveys between March and October 2020 and determined the seroprevalence in the same cohort of healthcare workers.

25 Feb 2021

Microbes could predict fatal outcomes in ventilated COVID-19 patients

The study "Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome" is available as a preprint on the medRxiv* server, while the article undergoes peer review.

25 Feb 2021

Study finds link between Googling symptoms and COVID-19 cases

Yasser El-Manzalawy and colleagues from Geisinger sought to find patterns with Google searches that could predict coronavirus spread. Based on Google search trends for nine symptoms, the team suggests their model can estimate the number of COVID-19 cases across the United States up to three weeks ahead.

25 Feb 2021

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Researchers in Switzerland and Germany have identified host cell factors required for coronavirus replication that could serve as targets for treatment with clinically-approved drugs.

25 Feb 2021

Study pinpoints potential transmission advantage of SARS-CoV-2 variant B.1.1.7

Researchers in the UK have shown that the increased transmissibility of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage B.1.1.7 that emerged in the UK during the coronavirus disease 2019 (COVID-19) pandemic does not appear to be the result of increased viral replication or immune escape.

25 Feb 2021

Study: Majority of COVID-19 hospitalizations attributable to four pre-existing conditions

A modeling study suggests a majority of adult COVID-19 hospitalizations nationwide are attributable to at least one of four pre-existing conditions: obesity, hypertension, diabetes, and heart failure, in that order.

25 Feb 2021

Texas Tech professor receives DARPA grant for developing indoor COVID-19 detector

Carbon monoxide is a colorless, odorless gas that can cause headaches, dizziness and even death in certain circumstances.

25 Feb 2021

New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates

Frontline staff at Norfolk and Norwich University Hospitals are among the first in the country to benefit from the rollout of more accurate saliva tests in a bid to curb Covid transmission rates.

25 Feb 2021

Abnormal sodium levels predict respiratory failure and mortality in hospitalized COVID-19 patients

Hospitalized patients with COVID-19 and abnormal sodium levels in the blood have an increased risk of experiencing respiratory failure or dying, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

25 Feb 2021

SARS-CoV-2 ORF7a mutation limits host immune suppression, finds study

Researchers have identified a high variability in the C-terminal end of ORF7a in SARS-CoV-2 sequences collected from around the globe. They noted that mutations result in a defective suppression of interferon and lowered replication rate.

25 Feb 2021

Have a case of a Covid variant? No one is going to tell you

Covid-19 infections from variant strains are quickly spreading across the U.S., but there's one big problem: Lab officials say they can't tell patients or their doctors whether someone has been infected by a variant.

25 Feb 2021

SNX-5422 could make an effective COVID-19 prophylactic, says study

SNX-5422 is a heat shock protein 90 (Hsp90) inhibitor currently undergoing clinical trials as a cancer therapeutic. A recent study examines the applicability of repurposing the drug towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication inhibition.

25 Feb 2021

Disease/Infection News

Simple pooled testing method can be an effective tool for curbing COVID-19 pandemic

Extensive use of opioid agonists can considerably reduce drug-related deaths

Antibody and T cell response to SARS-CoV-2 persist up to 8 months: Study of Ski Resort Ischgl

Pre-existing cross-reactive HCoV antibodies could protect against SARS-CoV-2

Microbes could predict fatal outcomes in ventilated COVID-19 patients

Study finds link between Googling symptoms and COVID-19 cases

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Study pinpoints potential transmission advantage of SARS-CoV-2 variant B.1.1.7

Study: Majority of COVID-19 hospitalizations attributable to four pre-existing conditions

Texas Tech professor receives DARPA grant for developing indoor COVID-19 detector

New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates

Abnormal sodium levels predict respiratory failure and mortality in hospitalized COVID-19 patients

SARS-CoV-2 ORF7a mutation limits host immune suppression, finds study

Have a case of a Covid variant? No one is going to tell you

SNX-5422 could make an effective COVID-19 prophylactic, says study

International cooperation is key to get equal access to COVID-19 vaccines

Research shows how antibodies attach to and block Zika virus

Study reports lasting immune response in convalescent COVID-19 patients

Study addresses COVID-19 pandemic concerns and guidelines for increasing food safety

COVID-19 Antigen Self-Test from Siemens Healthineers receives special approval in Germany for self-use by laypeople

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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