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One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

In a new study, published on the pre-print server medRxiv, an international team of researchers found that a one-dose policy may increase the potential for antigenic evolution. The study revealed that focusing on one dose may decrease infections in the short term, but longer-term outcomes rely on this immune strength.

8 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

In a recent medRxiv preprint publication, the team led by Professor Ravindra K. Gupta has assessed the real-world immune responses following the vaccination against the SARS-CoV-2. The team measured 1) IFN-gamma (interferon-gamma) T cell responses, 2) both total IgG Spike/ IgG Spike RBD (receptor binding domain) and 3) neutralizing antibody responses to Spike in sera.

8 Feb 2021

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

An analysis of Kaiser Permanente members in Northern California early in the COVID-19 pandemic found racial and ethnic disparities in the likelihood of testing positive for the coronavirus, but no significant disparities in mortality among those who were hospitalized.

8 Feb 2021

Study examines people's behavioral responses to face mask mandates during the pandemic

Face masks mandates have led people to spend less time at home, but whether this has exposed Americans to more risk is still a question, according to a new study published Thursday in Scientific Reports.

8 Feb 2021

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Researchers in the United States have identified specific immune correlates that might be key to ensuring that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects against not only disease, but also viral transmission and emerging variants.

8 Feb 2021

Moderna's COVID-19 vaccine effective against emerging variants

Researchers have conducted a study showing that the Moderna mRNA-1273 vaccine effectively protects against recently emerged variants of SARS-CoV-2 – the agent that causes COVID-19.

8 Feb 2021

Scientists produce active antigen in bacteria to help combat SARS-CoV-2

Researchers at the University of Nebraska Medical Center have developed a bacterial strategy for the expression and purification of the SARS-CoV-2 spike protein receptor-binding domain (RBD).

8 Feb 2021

Is a ten day isolation period for COVID-19 patients long enough?

In a new study researchers at the Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, Brazil, reported that mild COVID-19 patients can still be infectious at day 10 from the illness onset, even in the absence of symptoms.

8 Feb 2021

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

A team of researchers recently examined the SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epithelia.

8 Feb 2021

Can early use of colchicine reduce COVID-19 mortality?

The COVID-19 pandemic, caused by SARS-CoV-2, has caused well over 2.3 million deaths in a little over a year. A new meta-analysis reports the potential utility of colchicine in treating SARS-CoV-2 infection and forestalling severe and life-threatening inflammation of the lungs and other organs.

8 Feb 2021

Bioengineered ankyrin compounds show high in vitro activity against SARS-CoV-2 mutants

A new study describes the use of DARPin (designed ankyrin repeat proteins) therapeutic agents, each of which contains three different DARPin domains within the same molecule.

8 Feb 2021

Could graphene be an effective antiviral platform against SARS-CoV-2?

The urgent need for novel therapeutics has spurred investigation into broad-spectrum inhibitors of viral infection and replication. A new study describes the antiviral activity of synthesized graphene platforms, pointing to new therapeutic approaches against this virus.

8 Feb 2021

SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera

A recent study describes the experimental selection of SARS-CoV-2 mutants associated with resistance to antibodies, with important implications for vaccine development and therapeutic antibody use.

8 Feb 2021

Why the U.S. is underestimating Covid reinfection

Kaitlyn Romoser first caught Covid-19 in March, likely on a trip to Denmark and Sweden, just as the scope of the pandemic was becoming clear. Romoser, who is 23 and a laboratory researcher in College Station, Texas, tested positive and had a few days of mild, coldlike symptoms.

8 Feb 2021

Online searches can help predict later surges and declines in COVID-19 cases

Online searches for mobile and isolated activities can help to predict later surges and declines in COVID-19 cases, a team of researchers has found.

8 Feb 2021

Research from Israel shows mRNA vaccine is ~50% effective in reducing severe cases

In a report published on the pre-print server medRxiv, researchers at The Hebrew University of Jerusalem, the University of Trento, and the Racah Institute of Physics suggest that the shape of the outbreak in patients over 60 years old has changed because of the vaccinations.

8 Feb 2021

Americans plan to continue many of the pandemic precautions even after COVID-19

A new national survey of more than 2,000 Americans by The Ohio State University Wexner Medical Center finds most plan to continue many of the pandemic precautions in the name of public health, even when the pandemic is over.

8 Feb 2021

COVID-19 pandemic and nanotechnology

Writing in the International Journal of Nanomedicine, Professor Dongki Yang, from the Department of Physiology, Gachon University, South Korea, has reviewed the available knowledge on the coronaviruses, current approaches to tackle the newly emerged SARS-CoV-2 infection, and the innovative application of nanotechnology in the COVID-19 pandemic.

8 Feb 2021

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

A clinical study led by Dr. Jordan Feld, a liver specialist at Toronto Centre for Liver Disease, University Health Network (UHN), showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized.

8 Feb 2021

Disease/Infection News

One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

HIV: New therapeutic approach to restore the effectiveness of immune cells

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

Study examines people's behavioral responses to face mask mandates during the pandemic

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Moderna's COVID-19 vaccine effective against emerging variants

Scientists produce active antigen in bacteria to help combat SARS-CoV-2

Is a ten day isolation period for COVID-19 patients long enough?

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

Can early use of colchicine reduce COVID-19 mortality?

Bioengineered ankyrin compounds show high in vitro activity against SARS-CoV-2 mutants

Could graphene be an effective antiviral platform against SARS-CoV-2?

SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera

Why the U.S. is underestimating Covid reinfection

Online searches can help predict later surges and declines in COVID-19 cases

Research from Israel shows mRNA vaccine is ~50% effective in reducing severe cases

Americans plan to continue many of the pandemic precautions even after COVID-19

COVID-19 pandemic and nanotechnology

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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