Disease/Infection News

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SARS-CoV-2 delays interferon signaling in host cells

A team of scientists from Sweden and India has recently conducted a study to evaluate type I interferon (IFN-I) responses in cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The findings reveal that SARS-CoV-2 infection is associated with a delayed and dysregulated IFN-I response and that pretreatment with IFN-I can reduce the risk of SARS-CoV-2 infection.

7 Feb 2021

Symptomatic COVID-19 cases extremely low among YMCA summer campers in North Carolina

Cases of symptomatic COVID-19 were extremely low among children and staff at a network of YMCA summer camps held last year in North Carolina that took precautions like masking and physical distancing, with close to zero transmissions occurring at the camps, according to researchers at Duke Health, Weill Cornell Medicine and NewYork-Presbyterian.

7 Feb 2021

Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

A team of scientists from France has recently designed fluorescence in situ hybridization probes (CoronaFISH) to visualize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in infected cells. A detailed description of the probe design, validation, and application is currently available on the bioRxiv preprint server.

7 Feb 2021

Molecular surveillance of SARS-CoV-2 spike protein mutations using CovRadar

In a recent bioRxiv preprint research paper, scientists from Germany discuss how they made sequence information more easily accessible for epidemiologists and virologists.

7 Feb 2021

Subdominant SARS-CoV-2 epitopes key to understanding emerging variants

Researchers in the UK have conducted a study showing the importance of considering subdominant epitopes within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) when investigating neutralizing antibodies that target the virus.

7 Feb 2021

Orthodox Jewish in UK disproportionately impacted by COVID-19

Researchers have conducted a study showing an extremely high prevalence of severe acute respiratory coronavirus disease 2 (SARS-CoV-2) within a strictly Orthodox Jewish community in the UK.

7 Feb 2021

Mortality from sudden cardiac arrest is higher in COVID-19 patients

Sudden cardiac arrest is more often fatal in people with COVID-19, a new study shows. Those responsible for the research see the results as a wake-up call for the public and care providers alike.

6 Feb 2021

Scientists use the knowledge from climate system models to help fight COVID-19 pandemic

At the time of writing, coronavirus disease 2019 (COVID-19) is seriously threatening human lives and health throughout the world.

6 Feb 2021

New AI-assisted method could help counter COVID-19 mutations

USC researchers have developed a new method to counter emergent mutations of the coronavirus and hasten vaccine development to stop the pathogen responsible for killing thousands of people and ruining the economy.

6 Feb 2021

Study intends to evaluate the effectiveness of SARS-CoV-2 vaccine in 1200 health professionals

The data on the first 1000 health professionals, vaccinated on December 2020, reveals that 90% developed antibodies in the three weeks following the administration of the first dose.

6 Feb 2021

Anticancer drug may reduce mortality and speed up recovery for severe COVID-19 patients

Treating severe COVID-19 patients with the anticancer drug bevacizumab may reduce mortality and speed up recovery, according to a small clinical study in Italy and China that was led by researchers at Karolinska Institutet in Sweden between February and April 2020.

6 Feb 2021

Researchers develop systems to detect an atypical fungus responsible for severe pneumonia

The group led by Dr. Enrique J. Calderón - "Clinical Epidemiology and Vascular Risk" at the Institute of Biomedicine of Seville - IBiS/University Hospitals Virgen del Rocío and Macarena/CSIC/University of Seville, also a member of CIBERESP, participated in a project with researchers from CIBER-BBN, in which they developed systems to detect Pneumocystis jirovecii, an atypical fungus responsible for very severe pneumonia in immunosuppressed patients.

6 Feb 2021

How does SARS-CoV-2 infect the pancreas?

To understand how SARS-CoV-2 infects the pancreas and investigate its effects, a team of researchers used the human iPSC (induced pluripotent stem cells)-derived pancreatic cultures and analyzed the post-infection cellular and molecular changes.

5 Feb 2021

FDA schedules meeting to discuss EUA request for Janssen’s COVID-19 vaccine

The U.S. Food and Drug Administration has scheduled a meeting of its Vaccines and Related Biological Products Advisory Committee (VRBPAC) on Feb. 26, 2021, to discuss the request for emergency use authorization (EUA) for a COVID-19 vaccine from Janssen Biotech Inc.

5 Feb 2021

FDA continues to support the development of medical products to tackle new virus variants

As the public health agency responsible for regulating medical products, we must ensure that health care providers have the most up-to-date diagnostics, treatments and vaccines in their toolbox to fight this pandemic.

5 Feb 2021

Unmet treatment needs of female sex workers may contribute to HIV transmission in South Africa

The unmet HIV prevention and treatment needs of female sex workers and especially their male clients could contribute substantially to ongoing HIV transmission in South Africa, according to a new study led by researchers at the University of Bristol, UK.

5 Feb 2021

Study: Black people are less likely to live near hospitals that administer COVID-19 vaccines

Researchers at the University of Pittsburgh School of Pharmacy and West Health Policy Center found that in many parts of the country, Black people are less likely than white people to live near a pharmacy, clinic, hospital or health center that can administer COVID-19 vaccines.

5 Feb 2021

AI model aids early detection of severe COVID-19 infection in children

Children have been less impacted by COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2) than adults. But some children diagnosed with SARS-CoV-2 have experienced severe illnesses, including Multisystem Inflammatory Syndrome (MIS-C) and respiratory failure; nearly 80% of children with MIS-C become critically ill with a 2 to 4% mortality rate.

5 Feb 2021

Study provides new insight about integrating treatment for HIV and opioid use disorder in Vietnam

An assessment published this week in the journal The Lancet HIV provides new insight about an initiative to integrate treatment of opioid use disorder along with HIV in Vietnam.

5 Feb 2021

Natural reinfection with respiratory syncytial virus varies based on antibody response

Researchers at Baylor College of Medicine found that while most individuals responded to respiratory syncytial virus (RSV) natural reinfection with a typical sustained antibody response associated with protection, a few individuals surprisingly responded atypically, not being able to sustain the antibody response, which declined to levels that made the individuals susceptible to RSV reinfection.

5 Feb 2021

Disease/Infection News

SARS-CoV-2 delays interferon signaling in host cells

Symptomatic COVID-19 cases extremely low among YMCA summer campers in North Carolina

Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

Molecular surveillance of SARS-CoV-2 spike protein mutations using CovRadar

Subdominant SARS-CoV-2 epitopes key to understanding emerging variants

Orthodox Jewish in UK disproportionately impacted by COVID-19

Mortality from sudden cardiac arrest is higher in COVID-19 patients

Scientists use the knowledge from climate system models to help fight COVID-19 pandemic

New AI-assisted method could help counter COVID-19 mutations

Study intends to evaluate the effectiveness of SARS-CoV-2 vaccine in 1200 health professionals

Anticancer drug may reduce mortality and speed up recovery for severe COVID-19 patients

Researchers develop systems to detect an atypical fungus responsible for severe pneumonia

How does SARS-CoV-2 infect the pancreas?

FDA schedules meeting to discuss EUA request for Janssen’s COVID-19 vaccine

FDA continues to support the development of medical products to tackle new virus variants

Unmet treatment needs of female sex workers may contribute to HIV transmission in South Africa

Study: Black people are less likely to live near hospitals that administer COVID-19 vaccines

AI model aids early detection of severe COVID-19 infection in children

Study provides new insight about integrating treatment for HIV and opioid use disorder in Vietnam

Natural reinfection with respiratory syncytial virus varies based on antibody response

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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