Disease/Infection News

RSS

SARS-CoV-2 spike may impair antigen presentation by CD8 T cells

A new study published on the bioRxiv preprint server aims to identify specific viral epitopes on the spike protein from various regions of the spike protein and the T cell responses they evoke.

27 Jan 2021

Flu vaccinations for hospital workers can substantially reduce influenza-related deaths

Pneumonia and the flu kill tens of thousands of Americans each year, racking up billions of dollars in medical costs and even more in lost productivity.

27 Jan 2021

Suicide mosquitos may prevent the spread of Zika virus

In 2016, the World Health Organization called the Zika virus epidemic a "public health emergency of international concern" due to the virus causing birth defects for pregnant women in addition to neurological problems.

27 Jan 2021

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Now, in new research posted to the preprint server bioRxiv*, scientists use an experimental structure of the Spike RBD domain co-crystallized with part of the ACE2 receptor and several in silico methods to analyze the possible impacts of three amino acid replacements (Spike K417N, E484K, N501Y) concerning ACE2 binding.

27 Jan 2021

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Cell phone data that is routinely collected by telecommunications providers can reveal changes of behavior in people who are diagnosed with a flu-like illness, while also protecting their anonymity, a new study finds.

26 Jan 2021

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Using more than 100,000 virus genome sequences uploaded in the GISAID database, researchers found around 9,000 mutations in the virus spike protein RBD.

26 Jan 2021

Rapid reopening crucial in promoting the second wave of COVID-19

The spread of the coronavirus disease 2019 (COVID-19) has affected almost a hundred million people, with over two million deaths being attributed to this illness over the past 12 months or so. The only means to counter this so far has been through non-pharmaceutical interventions (NPIs).

26 Jan 2021

Antibodies and inflammatory markers may help identify COVID-19 cases and predict severity

A new preprint appearing on the medRxiv server describes the changes that occur in numerous antibodies and inflammatory molecules with age and at varying stages, or severity, of the infection and resulting illness. The results may help to predict the risk in individual cases.

26 Jan 2021

'Post-acute COVID-19 syndrome' likely to substantially impact NHS in England

Researchers in the UK have warned that cardiometabolic and pulmonary events among coronavirus disease 2019 (COVID-19) survivors following their discharge from hospital is likely to have an ongoing and substantial impact on the National Health Service (NHS) in England.

26 Jan 2021

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease.

26 Jan 2021

Moderna vaccine fully neutralizes new SARS-CoV-2 variants, study shows

Researchers in the United States have conducted a study showing that Moderna’s mRNA-1273 vaccine neutralizes all circulating variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tested to date.

26 Jan 2021

New recommendations to improve apps for controlling and monitoring NTDs

A study performed by the Universitat Oberta de Catalunya provided eight recommendations for improving the online technology to help with the treatment and diagnosis of neglected tropical diseases (NTDs).

26 Jan 2021

NIH launches database to collect information about COVID-19-related neurological problems

A new database will collect information from clinicians about COVID-19-related neurological symptoms, complications, and outcomes as well as COVID-19 effects on pre-existing neurological conditions.

26 Jan 2021

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

A new approach to mapping viral mutations that "escape" leading clinical antibodies has revealed mutations in the SARS-CoV-2 virus that allow it to evade treatments, including a single amino-acid mutation that fully escapes Regeneron's antibody cocktail.

26 Jan 2021

‘We’re not controlling it in our schools’: Covid safety lapses abound across US

Computer science teacher Suzy Lebo saw covid-19 dangers frequently in her Indiana high school: classes with about 30 students sitting less than 18 inches apart. Students crowding teachers in hallways. Students and staff members taking off their masks around others.

26 Jan 2021

Researchers develop method for presymptomatic COVID-19 detection

An encouraging new study by researchers at University College London, UK, reports the potential of a form of COVID-19 testing which can detect presymptomatic cases.

26 Jan 2021

Codon frequency optimization shows SARS-CoV-2 antiviral potential

A study conducted by researchers in the US has revealed that optimization of codon for bacterial expression causes the production of an inactive enzyme non-structural protein 12 (Nsp12), a catalytic subunit of RNA-dependent RNA polymerase of SARS-CoV-2.

26 Jan 2021

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Researchers have engineered an antibody that neutralizes SARS-CoV-2 with a potency that "rivals" current lead SARS-CoV-2 clinical neutralizing antibodies, and that also broadly neutralizes a range of clade 1 sarbecoviruses.

26 Jan 2021

Mutations in SARS-CoV-2 spike proteolytic cleavage sites may alter transmission dynamics

A study conducted by researchers at the University of Kentucky and the Washington University School of Medicine in the USA has revealed that mutations in the proteolytic cleavage site within the S2 subunit can alter the processing of the SARS-CoV-2 spike protein, affecting viral entry into host cells.

26 Jan 2021

Diabetes and glucose levels tied to increased risk of COVID-19 death

Researchers at Xijing Hospital, Fourth Military Medical University, Xi’an, China, found that diabetes and on-admission glucose levels may increase the risk of COVID-19 mortality.

26 Jan 2021

Disease/Infection News

SARS-CoV-2 spike may impair antigen presentation by CD8 T cells

Flu vaccinations for hospital workers can substantially reduce influenza-related deaths

Suicide mosquitos may prevent the spread of Zika virus

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Rapid reopening crucial in promoting the second wave of COVID-19

Antibodies and inflammatory markers may help identify COVID-19 cases and predict severity

'Post-acute COVID-19 syndrome' likely to substantially impact NHS in England

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

Moderna vaccine fully neutralizes new SARS-CoV-2 variants, study shows

New recommendations to improve apps for controlling and monitoring NTDs

NIH launches database to collect information about COVID-19-related neurological problems

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

‘We’re not controlling it in our schools’: Covid safety lapses abound across US

Researchers develop method for presymptomatic COVID-19 detection

Codon frequency optimization shows SARS-CoV-2 antiviral potential

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Mutations in SARS-CoV-2 spike proteolytic cleavage sites may alter transmission dynamics

Diabetes and glucose levels tied to increased risk of COVID-19 death

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest News