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Mount Sinai study shows strong immune response, durability of universal influenza virus vaccine

A vaccine that induces immune responses to a wide spectrum of influenza virus strains and subtypes has produced strong and durable results in early-stage clinical trials in humans, Mount Sinai researchers have found.

7 Dec 2020

How effective is social distancing in preventing SARS-CoV-2 transmission? A New York case study

A new study by researchers at the City University of Hong Kong examined the efficacy of non-pharmaceutical interventions (NPIs) on controlling the coronavirus disease 2019 (COVID-19) pandemic, the illness SARS-CoV-2 causes.

7 Dec 2020

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

A team of researchers at the Feinberg School of Medicine demonstrated that xylitol and grapefruit seed extract (GSE) could prevent SARS-CoV-2 infection. These can be used as a nasal spray to contain the spread of the coronavirus.

7 Dec 2020

The intranasal route of immunization may offer effective protection against SARS-CoV-2

Researchers at the School of Medicine, Washington University in Saint Louis, USA, showed that the intranasal route of immunization could provide a more efficient protection against SARS-CoV-2 compared to the intramuscular route (i.e. through ‘jabs’).

7 Dec 2020

Nearly 70% of diabetic patients in Indonesia experience disease management difficulties, study finds

Researchers from the Fatmawati General Hospital, Indonesia, recently determined the difficulties in diabetes management and how it impacts diabetes morbidity in Indonesia during the COVID-19 pandemic.

7 Dec 2020

Potential SARS-CoV-2 Mpro inhibitors identified by in silico screening

The search for effective inhibitors of SARS-CoV-2 is assuming new urgency as the fall/winter resurgence of the infection appears.

7 Dec 2020

D614/G614 variants of SARS-CoV-2 affect neuronal transmission; G614 better at membrane fusion

The COVID-19 pandemic is showing a strong comeback after an initial reduction in the number of cases, following energetic public health interventions.

7 Dec 2020

COVID-19 genetic risk variants impact diverse immune cell types and severe disease manifestations

A team of researchers from UK and US used the DICE database and 3D cis-interactome maps to generate a list of target genes and immune cell types that are most affected by the genetic variants associated with COVID-19 severity.

7 Dec 2020

WHO declares updates to forthcoming guidance on systematic screening for TB

In a Rapid Communication issued today, the World Health Organization (WHO) is announcing a number of updates to its forthcoming guidance on the systematic screening of tuberculosis (TB) disease.

7 Dec 2020

SARS-CoV-2 in Brazil shows gross genetic diversity

A new study discusses the presence of genetic diversity in SARS-CoV-2 circulating in Brazil, with reference to the susceptibility of the population to the virus.

7 Dec 2020

STE90-C11, a SARS-CoV-2 neutralizing antibody, shows high inhibition of RBD-ACE2 binding

In a new study, researchers describe the identification of a neutralizing antibody that binds to the RBD at the same site as the human host cell receptor.

7 Dec 2020

No evidence for risk of vaccine-driven virulence evolution in SARS-CoV-2

Beyond the morbidity and mortality associated with the pandemic, COVID-19 has paralyzed the global economy.

7 Dec 2020

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Remdesivir has been shown to target both RNA-dependent RNA polymerase and main protease of SARS-CoV-2 – resulting in a ‘double whammy’ effect.

7 Dec 2020

Associations between vaping and COVID-19: cross-sectional findings from the HEBECO study

Even though tobacco smoking is harmful to the lungs, some research suggests that smokers may be at reduced risk of COVID-19 infection.

7 Dec 2020

Evolution of the SARS-CoV-2 proteome in 3D during the first six months of the COVID-19 pandemic

In a recent study, researchers report how the SARS-CoV-2 proteome in 3D has evolved during the first six months of the COVID-19 pandemic.

7 Dec 2020

High-performance ELISA for serology in mild-moderate non-hospitalized COVID-19

A new study describes an ELISA assay that combines the detection of IgM, IgA, and IgG antibodies against the SARS−CoV−2 trimeric spike glycoprotein.

7 Dec 2020

Failure to comply with COVID-19 containment measures penalizes the compliant as well

The COVID-19 pandemic is now in its second wave and deaths are surpassing the spring peak as winter sets in over much of the northern hemisphere.

7 Dec 2020

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

A new study indicates that the topoisomerase 1 (Top1) is intimately related to the lethal inflammation associated with SARS-CoV-2 infection in a large proportion of cases.

7 Dec 2020

New biomarker of Alzheimer's may lead to enhanced diagnostic methods

Scientists at Washington University School of Medicine, Missouri, have identified a novel form of an Alzheimer’s protein in the spinal fluid of patients.

7 Dec 2020

Study finds binge drinking worsens with each week of lockdown

The results of a new study conducted during lockdown reveal that harmful drinking habits have increased during this time.

7 Dec 2020

Disease/Infection News

Mount Sinai study shows strong immune response, durability of universal influenza virus vaccine

How effective is social distancing in preventing SARS-CoV-2 transmission? A New York case study

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

The intranasal route of immunization may offer effective protection against SARS-CoV-2

Nearly 70% of diabetic patients in Indonesia experience disease management difficulties, study finds

Potential SARS-CoV-2 Mpro inhibitors identified by in silico screening

D614/G614 variants of SARS-CoV-2 affect neuronal transmission; G614 better at membrane fusion

COVID-19 genetic risk variants impact diverse immune cell types and severe disease manifestations

WHO declares updates to forthcoming guidance on systematic screening for TB

SARS-CoV-2 in Brazil shows gross genetic diversity

STE90-C11, a SARS-CoV-2 neutralizing antibody, shows high inhibition of RBD-ACE2 binding

No evidence for risk of vaccine-driven virulence evolution in SARS-CoV-2

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Associations between vaping and COVID-19: cross-sectional findings from the HEBECO study

Evolution of the SARS-CoV-2 proteome in 3D during the first six months of the COVID-19 pandemic

High-performance ELISA for serology in mild-moderate non-hospitalized COVID-19

Failure to comply with COVID-19 containment measures penalizes the compliant as well

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

New biomarker of Alzheimer's may lead to enhanced diagnostic methods

Study finds binge drinking worsens with each week of lockdown

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