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Study investigates best practices for mechanical ventilation in people with acute respiratory failure

It's a decision being made thousands of times over inside hospitals all around the country: is it time to place a patient struggling to breathe on a ventilator?

16 Nov 2020

Study: High-dose blood thinners have no additional benefit in COVID-19 patients

While COVID-19 infected patients should be treated with standard anticoagulation therapies, such as blood thinning medication, a new study by researchers at the George Washington University (GW) shows that anticoagulating patients at higher doses, without traditional medical indications to do so, may be ineffective and even harmful.

16 Nov 2020

Difference in antibody evolution could predict COVID-19 outcomes

For COVID-19, the difference between surviving and not surviving severe disease may be due to the quality, not the quantity, of the patients' antibody development and response, suggests a new Cell paper published by Galit Alter, PhD, a member of the Ragon Institute of MGH, MIT and Harvard.

16 Nov 2020

Global health leaders discuss the urgent funding needs of ACT Accelerator

Heads of state, global health leaders, scientists, and the private sector have come together at the Paris Peace Forum this week to discuss how to meet the urgent funding needs of the ACT Accelerator.

16 Nov 2020

Study: 68% of people believe they should ‘reach out’ to carers during coronavirus second wave

Amidst a coronavirus second wave, a study has found that 68% of people believe they should ‘reach out’ to carers more often – with 60% of respondents only asking carers how they are ‘now and again’, ‘rarely’ or ‘almost never’; leaving carers at risk of feeling forgotten.

16 Nov 2020

Primate model helps detect features of COVID-19 virus

Features of the SARS-CoV-2 virus causing COVID-19, which could be useful for developing vaccines and treatment strategies, were identified using a nonhuman primate model developed at the Korea Research Institute of Bioscience and Biotechnology (KRIBB).

16 Nov 2020

Study explains why conservatives and liberals differ on COVID-19 threat

Throughout the COVID-19 pandemic, political ideology has been perhaps the strongest predictor of consumers' perceptions of the coronavirus' threat.

16 Nov 2020

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

The turning point for people with COVID-19 typically comes in the second week of symptoms. As most people begin to recover, a few others find it increasingly difficult to breathe and wind up in the hospital.

16 Nov 2020

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Researchers at Georgetown University Medical Center have successfully used molecules comprised of small strands of RNA to shut down the production of destructive proteins generated by the COVID-19 virus.

16 Nov 2020

New data highlights safety concerns on rAAV vectors used in gene therapy

New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy.

16 Nov 2020

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

De'Broski Herbert has a philosophy that's guided his career researching helminths, or parasitic worms, and their interaction with their hosts' immune systems: "Follow the worm."

15 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

The paper, put together by a team of scientists based in the United Kingdom and Italy, also underscored the need for healthcare policies to account for the very real possibility of inadequate protective personal equipment (PPE), staff and hospital capacity, aggravated by the increased number of pediatric infections.

15 Nov 2020

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

A new paper published in the journal Science of the Total Environment on November 10, 2020, discusses the reality of the virus’s wastewater transmission. Overall, the researchers found that wastewater transmission would have a disproportionate impact on countries with low development indices.

15 Nov 2020

Study looks at SARS-CoV-2 RNA contamination in COVID-19 isolation ward of a hospital

To try and shed more light on SARS-CoV-2’s transmission, a research group based in Italy examined a COVID-19 isolation ward in a Milan hospital to evaluate the level of contamination present in the air and on surfaces with SARS-CoV-2 RNA (the virus’s genetic material).

15 Nov 2020

Multi-faceted COVID-19 strategy can prevent infections, save lives in resource-challenged countries

A public health strategy that combines contact tracing and community-based screening with isolation and quarantine centers can substantially reduce infections, hospitalizations and deaths from COVID-19 while being cost-effective in low-and-middle-income countries like South Africa, a study by Massachusetts General Hospital has found.

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

New methodology predicts mutation hotspots in SARS-CoV-2 virus

Researchers in Sweden and China have presented a new methodology for predicting mutation “hotspot” sites within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Arthritis drug may improve COVID-19 survival among elderly patients

A type of arthritis drug may reduce the risk of dying for elderly patients with COVID-19.

15 Nov 2020

Researchers identify prognostic markers that could guide COVID-19 management

A team of researchers in Europe has created a comprehensive data resource to help improve understanding of how coronavirus disease 2019 (COVID-19) progresses and how biomarkers could be used to guide treatment approaches and disease monitoring.

15 Nov 2020

Disease/Infection News

Study investigates best practices for mechanical ventilation in people with acute respiratory failure

Study: High-dose blood thinners have no additional benefit in COVID-19 patients

Difference in antibody evolution could predict COVID-19 outcomes

Global health leaders discuss the urgent funding needs of ACT Accelerator

Study: 68% of people believe they should ‘reach out’ to carers during coronavirus second wave

Primate model helps detect features of COVID-19 virus

Study explains why conservatives and liberals differ on COVID-19 threat

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

New data highlights safety concerns on rAAV vectors used in gene therapy

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

Study looks at SARS-CoV-2 RNA contamination in COVID-19 isolation ward of a hospital

Multi-faceted COVID-19 strategy can prevent infections, save lives in resource-challenged countries

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

New methodology predicts mutation hotspots in SARS-CoV-2 virus

Arthritis drug may improve COVID-19 survival among elderly patients

Researchers identify prognostic markers that could guide COVID-19 management

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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