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New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19, from small samples of saliva, according to a study led by Bloomberg School researchers.

15 Nov 2020

Antidepressant may prevent worsening of COVID-19 infection, study suggests

The antidepressant fluvoxamine appears to prevent COVID-19 infections from worsening and may help keep patients out of the hospital, a trial based on research from the University of Virginia School of Medicine suggests.

15 Nov 2020

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

The study, which appeared in the Journal of Taibah University Medical Sciences, shows that the SARS-CoV-2 may behave akin to the CNS pathogenic mechanism of JEV and HIV during the early stages of infection.

15 Nov 2020

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

A recent study published in the International Journal of Infectious Diseases has explained the lower prevalence of coronavirus disease 2019 (COVID-19) in sub-Saharan Africa compared to that in the US, Europe, and Asia.

15 Nov 2020

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

A single-center study from Wuhan in China presents ultrasound imaging evidence supporting the notion that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause infection of the testis or epididymis – and put patients at risk for further complications. The paper can be found in the Journal of Ultrasound in Medicine.

15 Nov 2020

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

Researchers in Korea and the United States have identified novel genetic variants that demonstrate the active mutational progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Nov 2020

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

With the coronavirus disease 2019 (COVID-19) pandemic infecting over 52.7 million people around the world, and killing over 1.2 million, a large amount of research has tried to better understand immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

15 Nov 2020

Harnessing proteomics could improve therapeutic approaches to COVID-19

A research group in India has recently described how the field of proteomics could be pivotal in helping to tackle the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

A research team from the Engelhardt Institute of Molecular Biology in Russia have shown that Nsp1 – a non-structured protein present in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen – stimulates translation termination in the stop codon recognition stage. Studying and developing drugs that compete with Nsp1 for binding with the termination complex could therefore be a potential strategy for fighting against coronavirus disease 2019 (COVID-19).

15 Nov 2020

Transmission of SARS-CoV-2 among US marine recruits after quarantine: A case study

A team of researchers at the Naval Medical Research Center, Silver Spring, USA, analyzed the risk of transmission of SARS-CoV-2 among marine recruits. Their study titled, “SARS-CoV-2 Transmission among Marine Recruits during Quarantine,” was published in the latest issue of the New England Journal of Medicine.

15 Nov 2020

Some people had non-neutralizing antibodies against SARS-CoV-2 prior to COVID-19

A recent study examined several medical records and found that while past human coronavirus exposures are not linked to decreased SARS-CoV-2 infections, they are associated with reduced COVID-19 severity.

12 Nov 2020

250,000 cases of child abuse or neglect may have gone unreported in U.S. COVID pandemic

A recent study published in the journal Child Abuse and Neglect has reported that the number of child maltreatment reports and child welfare interventions decreased significantly in New York City during the initial phase of the coronavirus disease 2019 (COVID-19) pandemic.

12 Nov 2020

Hantavirus can also be transmitted by wild or domesticated rats

A group of researchers from Charité - Universitätsmedizin Berlin have confirmed Germany's first-ever case of animal-to-human transmission involving a specific species of virus known as the 'Seoul virus'.

12 Nov 2020

Mink farms potential viral reservoirs for SARS-CoV-2

A new study published in the journal Science in November 2020 describes the probable transmission of the virus between farmed minks and humans working on the mink farm, even with biosecurity measures in place and the culling of infected farms as soon as an infection is reported.

12 Nov 2020

Bispecific sybodies show potential against SARS-CoV-2

As the search for effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues, a new study published on the preprint bioRxiv in November 2020 discusses the role of synthetic nanobodies or sybodies in neutralizing the virus by binding to its receptor-binding domain (RBD) on the spike protein.

12 Nov 2020

World Health Assembly endorses new road map for neglected tropical diseases for 2021−2030

Today, delegates attending the virtual session of the Seventy-third World Health Assembly overwhelmingly endorsed the new road map for neglected tropical diseases (NTDs) for 2021−2030.

12 Nov 2020

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

A new study published on the preprint server bioRxiv in November 2020 describes the virus's N protein as a promising epitope for serology.

12 Nov 2020

Global measles cases increase to 869,770 in 2019

Measles surged worldwide in 2019 reaching highest number of reported cases in 23 years. Highlighted in a publication by the World Health Organization and the United States Centers for Disease Control and Prevention, measles cases worldwide increased to 869,770 in 2019, the highest number reported since 1996 with increases in all WHO regions.

12 Nov 2020

SARS-CoV-2-induces temporary loss of smell in mice

Now, a new study published on the preprint server bioRxiv in November 2020 presents the onset of olfactory dysfunction (loss of smell) in mice infected with the virus, examining this process at the cellular level. In doing so, this study throws more light on this curious symptom and COVID-19’s manifestations outside the lungs.

12 Nov 2020

Disease/Infection News

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

Antidepressant may prevent worsening of COVID-19 infection, study suggests

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

Harnessing proteomics could improve therapeutic approaches to COVID-19

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

Transmission of SARS-CoV-2 among US marine recruits after quarantine: A case study

Some people had non-neutralizing antibodies against SARS-CoV-2 prior to COVID-19

250,000 cases of child abuse or neglect may have gone unreported in U.S. COVID pandemic

Hantavirus can also be transmitted by wild or domesticated rats

Mink farms potential viral reservoirs for SARS-CoV-2

Bispecific sybodies show potential against SARS-CoV-2

World Health Assembly endorses new road map for neglected tropical diseases for 2021−2030

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

Global measles cases increase to 869,770 in 2019

SARS-CoV-2-induces temporary loss of smell in mice

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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