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Scientists compare ACE2 interaction with SARS-CoV-2 across species

Like other pathogenic coronaviruses, SARS-CoV-2 crossed the species barrier to cause human disease. This fact motivated the current study, published on the preprint server bioRxiv* in October 2020, which explores the way coronaviruses engage their host cell receptors in a range of animals.

28 Oct 2020

Researchers describe factors that reduce placenta's capacity to protect fetus from zika virus

Genetic factors that reduce the placenta's capacity to protect the fetus from the zika virus are described by Brazilian researchers in an article published in PLOS Neglected Tropical Diseases.

28 Oct 2020

Structure and mechanisms of ribosomal frameshifting during SARS-CoV-2 translation

The structure of a 3’ stimulatory pseudoknot in the viral genome or by itself has been proposed recently. Researchers report the structure and mechanisms of mammalian ribosomes during translation of the -1 frameshifting of the SARS-CoV-2 viral genome in a new study published on the preprint server bioRxiv.

28 Oct 2020

Researchers demonstrate potent antibody that fights against coronavirus

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus's distinctive spikes and induces critical pieces of those spikes to break off in the process.

28 Oct 2020

Scientists design 3D map to understand the behavior of novel coronavirus

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

28 Oct 2020

Lianhuaqingwen capsule is effective for treating COVID-19 pneumonia

Lianhuaqingwen (LHQW) capsule, a herb medicine product, has been clinically proved to be effective in coronavirus disease 2019 (COVID-19) pneumonia treatment. However, human exposure to LHQW components and their pharmacological effects remain largely unknown.

28 Oct 2020

Study: Coronaviruses are adept at imitating human immune proteins involved in COVID-19

Coronaviruses are adept at imitating human immune proteins that have been implicated in severe COVID-19 disease, a study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

28 Oct 2020

Mathematical model for COVID-19 allows for dynamic social distancing and relaxation

Recently, researchers from York University, Toronto, Canada, presented a mathematical model for COVID-19 comprising groups of people with various levels of exposure to the disease based on data from Ontario, Canada. Their work is published on the preprint server medRxiv.

27 Oct 2020

Furin cleavage site and D614G on SARS-CoV-2 spike evolved to balance infectivity, stability, cytopathicity

SARS-CoV-2 is the causative agent of COVID-19 disease, currently raging across the world. The virus has now infected more than 43.89 million individuals and claimed over 1.16 million lives. The study titled, "Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects," is released on the preprint server bioRxiv* in October 2020.

27 Oct 2020

Gut's immune response to SARS-CoV-2 very different from the lung

Megan L. Stanifer et al. study the immune response in the human gut upon SARS-CoV-2 infection. The study published as a bioRxiv* preprint reveals a robust proinflammatory response: a cell type-specific or a tissue-specific regulation of interferon-mediated signaling during SARS-CoV-2 infection.

27 Oct 2020

COVID vaccine misinformation lowering people's intent to get vaccinated

A new study by researchers at the Imperial College London and the London School of Hygiene and Tropical Medicine aimed to determine how online misinformation impacts COVID-19 vaccine uptake intent. Further, the team wanted to identify socioeconomic groups at a higher risk of not getting vaccinated and those who are most susceptible to online misinformation.

27 Oct 2020

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

27 Oct 2020

Bigger households associated with greater odds of SARS-CoV-2 transmission

Household transmission plays a pivotal role in the spread of SARS-CoV-2. The study recommends that it is essential for people to get tested immediately or as soon as symptoms appear. This way, they will take precautions to protect the other members of the family.

27 Oct 2020

Rapid CD169 assay for COVID-19 screening

Researchers in France have conducted a study demonstrating the sensitivity of a rapid flow cytometry assay that could be used to screen for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

27 Oct 2020

Research examines COVID-19 transmission patterns in Georgia, U.S.

Researchers from Emory University and the Georgia Department of Public Health have shown that the transmission of coronavirus disease 2019 (COVID-19) in the state of Georgia earlier this year changed over time and varied by age.

27 Oct 2020

Study finds a significant drop in death rates among people with severe COVID-19 in England

Death rates from people with severe COVID-19 in hospital have dropped to around a half of the rate at the peak of the pandemic, new research has revealed.

27 Oct 2020

Research on autophagy and coronavirus, implicates ULK1

Researchers from the University of British Columbia have discovered that the betacoronavirus-encoded papain-like protease disrupts autophagy, partly by targeting ULK1. Their work is reported on the preprint server bioRxiv* in October 2020.

27 Oct 2020

Black Hispanic individuals have worse COVID-19 outcomes

Results from a new study led by Boston Medical Center (BMC) demonstrate the disproportionate impact of COVID-19 on Hispanic groups within the US, with the most severe outcomes, including death and intensive care, among Hispanic Black individuals.

27 Oct 2020

Researchers study the dynamics of airborne transmission

The continued increase in COVID-19 infection around the world has led scientists from many different fields, including biomedicine, epidemiology, virology, fluid dynamics, aerosol physics, and public policy, to study the dynamics of airborne transmission.

27 Oct 2020

Scientists use new approach to chart the spread of drug-resistant hospital bacteria

Scientists have used genome sequencing to reveal the extent to which a drug-resistant gastrointestinal bacterium can spread within a hospital, highlighting the challenge hospitals face in controlling infections.

27 Oct 2020

Disease/Infection News

Scientists compare ACE2 interaction with SARS-CoV-2 across species

Researchers describe factors that reduce placenta's capacity to protect fetus from zika virus

Structure and mechanisms of ribosomal frameshifting during SARS-CoV-2 translation

Researchers demonstrate potent antibody that fights against coronavirus

Scientists design 3D map to understand the behavior of novel coronavirus

Lianhuaqingwen capsule is effective for treating COVID-19 pneumonia

Study: Coronaviruses are adept at imitating human immune proteins involved in COVID-19

Mathematical model for COVID-19 allows for dynamic social distancing and relaxation

Furin cleavage site and D614G on SARS-CoV-2 spike evolved to balance infectivity, stability, cytopathicity

Gut's immune response to SARS-CoV-2 very different from the lung

COVID vaccine misinformation lowering people's intent to get vaccinated

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

Bigger households associated with greater odds of SARS-CoV-2 transmission

Rapid CD169 assay for COVID-19 screening

Research examines COVID-19 transmission patterns in Georgia, U.S.

Study finds a significant drop in death rates among people with severe COVID-19 in England

Research on autophagy and coronavirus, implicates ULK1

Black Hispanic individuals have worse COVID-19 outcomes

Researchers study the dynamics of airborne transmission

Scientists use new approach to chart the spread of drug-resistant hospital bacteria

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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