Drug Discovery & Pharmaceuticals

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Modeling Alzheimer’s Disease Using Microfluidics

An interview with Dr. Joseph Park, the incorporation of astrocytes into the Alzheimer’s-in-a-dish culture system and it's applications in drug development.

24 Oct 2018

How a single mutation can devastate cellular function

A scientist has shown how a single mutation in a protein found in astrocytes reproduces fibrous globs that devastate cellular function.

23 Oct 2018

Gut microbiota at infancy predict risk of obesity in later life

Researchers have provided further evidence to support the link between the gut microbiota in infancy and the risk of becoming overweight or obese in later life

23 Oct 2018

Epigenetic modifications may contribute to Alzheimer's Disease

Scientists report epigenetic modifications in the brains of patients with Alzheimer's, after observing differences in histone acetylation across the genome.

22 Oct 2018

New protein sequencing technique could revolutionize biomedical research

Scientists have developed a new, low-throughput technique that allows individual proteins to be identified. It is called single molecule fluorosequencing.

22 Oct 2018

Scientists uncover key regulator of mTORC1 in cancer growth

Scientists have discovered that Src is needed for activation of mTORC1, a major regulator of cellular metabolism, growth and proliferation in cancer.

19 Oct 2018

Breast Cancer as a Dynamic Disease

An interview with Dr. Andrew Ewald, discussing the influence of the myoepithelium on breast cancer growth and the importance of studying metastasis.

19 Oct 2018

Genetically modifying zebrafish provides numerous, highly accurate disease models

Research published today describes how zebrafish can be genetically engineered to produce more accurate models of human disease.

18 Oct 2018

Scientists obtain clearest ever image of Ebola virus protein

For the first time, researchers have managed to image the structure of a central component of the Ebola virus.

17 Oct 2018

Scientists create synthetic tissue capable of synchronized beating

A team of chemists at the University of Bristol have developed a prototissue that is capable of synchronized beating when it is heated and cooled.

16 Oct 2018

Yale researchers develop way to attack RNA with small-molecule drugs

Yale researchers have developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.

15 Oct 2018

Modeling Non-Numerical Data in Systems Biology

An interview with Dr. Eshan Mitra, discussing the importance of computer models in biology and the development of a more accurate model of the RAF phosphorylation pathway.

15 Oct 2018

'Digital brain' recreates protein trafficking in the brain

Researchers have developed a digital 3D brain demonstrating how the toxic proteins involved in neurodegenerative diseases are transported through the brain.

12 Oct 2018

Scientists use haploid stem cells to produce mice with same-sex parents

In a new study, Chinese researchers were able to produce healthy mouse pups with two mothers. The research involved the use of haploid embryonic stem cells.

12 Oct 2018

Researchers uncover how common pain reliever causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins at an amino acid called cysteine.

11 Oct 2018