Drug Discovery & Pharmaceuticals

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Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Researchers have successfully used prenatal gene editing (CRISPR-Cas9) to prevent a fatal metabolic disorder in an animal model.

8 Oct 2018

Scientists call for microbiota vault of healthy bacteria

A team of researchers are gathering bacteria from across the world to create a microbiota vault containing healthy bacteria from the human gut and skin.

5 Oct 2018

New method for quantification of liposome formulated drugs

Postnova Analytics has published an application study that describes a new method for quantification of liposome encapsulated drug using Centrifugal Field-Flow Fractionation

From Postnova Analytics 5 Oct 2018

New method for studying the cell nucleus could improve disease detection

Researchers at New York University have found a way to measure the physical properties of the nucleus and its constituents in live human cells.

5 Oct 2018

A Single Platform to Sequence All Monoclonal Antibody Proteins

Having a single platform to sequence all monoclonal antibody proteins provides researchers with key information for research, development and drug discovery

From Rapid Novor Inc 3 Oct 2018

Researchers create pseudo-embryos that mimic human embryos

Researchers have created murine pseudo-embryos that form the three major axes of the body and are able to accurately mimic human embryos.

3 Oct 2018

New search technique efficiently identifies antibiotic compounds

If you're looking for a needle in a haystack, it's best to know what hay looks like. An international team of researchers has applied this idea to the search for new pharmaceuticals, developing a technique that reduces the chances of simply rediscovering known compounds.

3 Oct 2018

Novel method promises to reduce production costs for potent form of vitamin K

In an innovative study that promises to reduce production costs for the most potent form of vitamin K -- Menaquinone-7, Penn State researchers have developed a novel method to enhance the fermentation process that creates the supplement by agitated liquid fermentation in a biofilm reactor.

3 Oct 2018

Newly discovered protein shown to cause amyloid-beta plaques in Alzheimer's

Scientists have discovered that a potassium channel called KCNB1 can trigger the formation of amyloid-beta plaques seen in Alzheimer's disease.

2 Oct 2018

Bioaxone Biosciences receives Fast-Track SBIR grant to assess potential of Rho Kinase 2 inhibitor

BioAxone BioSciences, Inc. announced today the receipt of a Fast-Track grant from the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, as part of the agency's Small Business Innovation Research Program.

27 Sep 2018

Crown Bioscience announces successful validation of well-characterized prostate cancer PDX models

Crown Bioscience, a global drug discovery and development services company providing translational platforms to advance oncology, inflammation, cardiovascular and metabolic disease research, has announced the addition of unique, well characterized, fully annotated patient-derived xenograft models of prostate cancer.

27 Sep 2018

Not all P53 mutations cause skin cancer

Today, scientists have explained for the first time why not all UV-induced, P53 mutated skin cells develop into cancer.

27 Sep 2018

New cell-based profiling service from RBC and Promega

A new cell-based profiling service for drug discovery has been announced by RBC and Promega Corporation.

From Promega Corporation 27 Sep 2018

New robot could improve drug delivery in the body

Researchers have developed a tiny, soft robot that can carry heavy loads and is capable of adapting to adverse environments.

26 Sep 2018

Researchers to build 3D map of human cells and tissues

Researchers at CMU are working with the NIH to build 3D map of human cells and tissues as part of the Human BioMolecular Atlas Program (HuBMAP).

26 Sep 2018

Safe and reliable way to handle useful but foul-smelling gas in chemical synthesis

The chemical element sulfur is an important constituent in many pharmaceuticals and, consequently, it is desirable to be able to introduce sulfur-containing fragments efficiently in a broad range of chemical compounds.

21 Sep 2018

Study provides insights into development of special-purpose cosmetic products

A research team, affiliated with UNIST has examined the rates of liquid penetration on rough or patterned surfaces, especially those with pores or cavities.

18 Sep 2018

Mitochondrial pathway found to be involved in breast cancer

Researchers have discovered a molecular pathway that controls the movement of mitochondria within breast cancer cells and influences invasiveness.

12 Sep 2018

Study opens up new possibilities for designing novel medicines

A study by the Computational Biochemistry Research Group of the Universitat Jaume I of Castellón, Spain, shows that enzyme activity depends on electrostatic properties, as opposed to mechanical ones.

11 Sep 2018

How 'bad' bacteria gain an upper hand in the human gut

A study has revealed that the bacterium C. difficile gains a competitive advantage over protective bacteria in the human gut by producing para-cresol.

11 Sep 2018