Drug Discovery & Pharmaceuticals

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Russian researchers come up with faster method to discover antibiotics

Russian biochemists have identified a promising new class of antibiotics. Having studied over 125,000 molecules, they found that 2-pyrazol-1-yl-thiazole derivatives exhibit antibacterial properties.

26 Sep 2019

Mechanisms behind antibiotic resistance captured on video for the first time

Scientists have established the cause of antibiotic-resistance in bacteria on video, and the findings contradict previous beliefs.

26 Sep 2019

'A new era of drug discovery’: Company develops drug using AI

For the first time, a company has discovered a drug target and corresponding candidate using artificial intelligence (AI).

26 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Scientists identify new family of drugs which could combat prostate cancer

A new family of drugs which inhibit the activity of a protein associated with prostate and other cancers has been reported by scientists from the University of Bath.

20 Sep 2019

Researchers discover potential approach to treating diabetic retinopathy

Boston University researchers have identified an enzymatic precursor that is toxic to retinal cells and could be used in new treatments for diabetic retinopathy.

20 Sep 2019

Alzheimer’s drug an interesting candidate for the treatment of parasitic Chagas disease

Researchers have discovered that an Alzheimer's drug could serve as a starting point in treating Chagas disease.

20 Sep 2019

Brain tumors hijack healthy neurons in order to grow

Scientists have discovered that brain tumors integrate themselves with the brain’s healthy neuronal network to support their growth.

19 Sep 2019

New uses for CBD in genetic brain disorder

A new study has revealed that cannabidiol can help people with a rare brain condition called Angelman syndrome to improve their behavioral traits and to control seizures.

19 Sep 2019

NUS chemists develop new anti-cancer drug with less renal toxicity

A team of pharmacists and chemists from the National University of Singapore has developed a new anti-cancer drug that has less toxic effects to the kidneys.

18 Sep 2019

New AI-guided robotic platform for automation of synthetic biological molecules

A cross-disciplinary team of MIT researchers have published details of an artificial intelligence (AI) guided robotic platform for flow synthesis of small molecule organic compounds. The paper appeared in the August 9, 2019 issue of Science.

17 Sep 2019

Accelerating drug discovery process to help patients

An international research team has developed a new strategy that can predict the potential clinical implications of new therapeutic compounds based on simple cellular responses.

15 Sep 2019

New reaction enables edition of organic molecule's skeletons

Since Friedrich Wohler synthesized urea (by accident) back in 1828, chemical synthesis - and organic synthesis for that - has been a driving force in pharmaceutical innovation.

13 Sep 2019

CRISPR may explain why so many experimental cancer drugs fail

Scientists have used CRISPR–Cas9 to investigate how ten cancer drugs interact with their protein target, revealing some intriguing findings.

13 Sep 2019

Researchers develop more efficient method to produce building blocks needed for drugs

Researchers at Tokyo University of Agriculture and Technology in Japan and Mount Allison University in Canada have developed a more efficient method to produce the building blocks needed for antibiotics and cancer treatment drugs.

12 Sep 2019

Scientists use CAR-T cells to reverse cardiac fibrosis

Scientists have used CAR-T cell therapy to treat cardiac fibrosis, a key part of heart disease and cardiac arrest.

12 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

VUMC partners with Batavia to move promising Zika antibody therapy closer to the clinic

Researchers at Vanderbilt University Medical Center are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.

6 Sep 2019

Lundbeck chooses Discngine’s 3decision platform for handling complex protein-ligand 3D structure data

Discngine, a software company specialized in developing applications for life sciences research, today announces that Lundbeck has selected its proprietary 3decision collaborative platform to manage the pharma company’s structural knowledge related to protein and ligand 3D structures.

5 Sep 2019

Potential drug could revolutionize the treatment of neurological conditions

The international team of scientists from Gero Discovery LLC, the Institute of Biomedical Research of Salamanca, and Nanosyn, Inc. has found a potential drug that may prevent neuronal death through glucose metabolism modification in stressed neurons.

28 Aug 2019