Genomics

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Enzyme acts as a sensor to find the hiding spots of viruses

While some types of RNA viruses cloak themselves to hide inside a cell and create copies of themselves, a "detective enzyme" might be attuned to their whereabouts. A slight variation in their genomic code gives some people's cells the capacity to produce this sensor.

14 Aug 2021

Novel CRISPR-based technique could inspire a new class of medical diagnostics

Scientists have repurposed the genetic modification technology CRISPR to identify antibodies in patient blood samples in a move that could inspire a new class of medical diagnostics in addition to a host of other applications.

13 Aug 2021

Researchers identify genetic program in fruit fly that protects neurons from degeneration

Researchers at the University of Bonn have identified a previously unknown genetic program in the fruit fly. The genetic material involved controls the development of the neurons while also protecting them from degeneration.

13 Aug 2021

Study finds new pair of gene variants that causes sudden onset of hypertension in pregnant women

An international study, led by researchers from Queen Mary University of London and St Bartholomew's Hospital, has found a unique pair of gene variants that causes sudden onset high blood pressure in pregnant women.

12 Aug 2021

Researchers identify human sperm mutations that can cause disease in children

Throughout development, life and the processes of aging, all human cells accumulate mutations, resulting in what is called mosaicism, a condition in which different cells in the same person have different DNA sequences or genetic makeup.

12 Aug 2021

Study unlocks genetic treasure chest for chronic kidney disease

Despite impacting an estimated 850 million people and being responsible for 1 in 60 deaths worldwide, few treatments are available for chronic kidney disease.

12 Aug 2021

New genomic and geological mapping tool may help track the deadliest of foodborne pathogens

Among the deadliest of foodborne pathogens, Listeria monocytogenes soon may become easier to track down in food recalls and other investigations, thanks to a new genomic and geological mapping tool created by Cornell University food scientists.

11 Aug 2021

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

A study at Tampere University has identified one possible epigenetic mechanism through which the conditions at conception may affect the health of an individual in later life.

10 Aug 2021

Novel gene could make plants more tolerant to higher temperatures

With temperatures rising globally, agricultural crops are feeling the stress. Warmer weather can cause a large reduction in crop yield. The Kendal Hirschi Lab at Baylor College of Medicine recently had a patent approved for a gene to make plants more tolerant to higher temperatures.

10 Aug 2021

Study finds altered brain gene expression patterns in people with opioid use disorder

The epidemic of opioid abuse affects millions of people worldwide, but researchers know surprisingly little about the molecular changes caused by opioids in the human brain.

10 Aug 2021

Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Researchers from the group of Hans Clevers (Hubrecht Institute) corrected mutations that cause cystic fibrosis in cultured human stem cells.

9 Aug 2021

Study may provide a new therapeutic target for treatment of LUAD patients

Aging-US published "A novel ferroptosis-related gene signature for prognostic prediction of patients with lung adenocarcinoma" which reported that RNA-seq transcriptome data of LUAD patients were obtained from The Cancer Genome Atlas database.

9 Aug 2021

Genetic testing in ambulatory cardiology clinics can benefit many patients

A person's genetics may hold the key to early intervention in cardiovascular disease, leading to better outcomes in patient care.

9 Aug 2021

New streamlined approach for high-coverage genome sequencing of single yeast cells

A single cell can reveal much about the biological world through genomic sequencing. Scientists can compare a single, isolated cell to other samples, analyzing the differences and similarities to better understand how the organisms originated and evolved -; or even to discover entirely new species.

6 Aug 2021

New procedure increases the sensitivity to detect viruses in blood samples from healthy people

The Institute for Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the Spanish National Research Council (CSIC), has developed a procedure that increases the sensitivity to detect viruses in blood samples from healthy people, in addition to reducing the effect of contaminations.

6 Aug 2021

DNA recovered from illicit drug capsules could be used to track down criminal syndicates

Forensic scientists have for the first time shown that DNA can be recovered from the surface of capsules after just 15 seconds of contact by drug manufacturers & dealers – making it possible for law enforcement agencies to track down criminal syndicates around the world.

6 Aug 2021

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

In collaboration with Northwestern Medicine investigators, an international multi-center study has identified genetic factors associated with SARS-CoV-2 infection and COVID-19 severity, according to findings published in Nature.

6 Aug 2021

UAB researchers identify potential therapeutic target for ovarian cancer

A gene called DOT1L appears to play a role in progression and severity of ovarian cancer, and inhibitors of the DOT1L enzyme may offer a new therapeutic approach for the disease, University of Alabama at Birmingham researchers say in a study published in the journal Oncogenesis.

5 Aug 2021

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

New DNA writing technique can precisely and efficiently edit bacterial genomes

Biological engineers at MIT have devised a new way to efficiently edit bacterial genomes and program memories into bacterial cells by rewriting their DNA.

5 Aug 2021

Genomics

Enzyme acts as a sensor to find the hiding spots of viruses

Novel CRISPR-based technique could inspire a new class of medical diagnostics

Researchers identify genetic program in fruit fly that protects neurons from degeneration

Study finds new pair of gene variants that causes sudden onset of hypertension in pregnant women

Researchers identify human sperm mutations that can cause disease in children

Study unlocks genetic treasure chest for chronic kidney disease

New genomic and geological mapping tool may help track the deadliest of foodborne pathogens

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

Novel gene could make plants more tolerant to higher temperatures

Study finds altered brain gene expression patterns in people with opioid use disorder

Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Study may provide a new therapeutic target for treatment of LUAD patients

Genetic testing in ambulatory cardiology clinics can benefit many patients

New streamlined approach for high-coverage genome sequencing of single yeast cells

New procedure increases the sensitivity to detect viruses in blood samples from healthy people

DNA recovered from illicit drug capsules could be used to track down criminal syndicates

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

UAB researchers identify potential therapeutic target for ovarian cancer

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

New DNA writing technique can precisely and efficiently edit bacterial genomes

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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