Genomics

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Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

16 Sep 2021

UTHSC researcher receives funding to advance The Cancer Genome Atlas project

Neil Hayes, MD, MPH, director of the Center for Cancer Research at the University of Tennessee Health Science Center, is one of two principal investigators for a $1.8 million grant that extends the work of The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

16 Sep 2021

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

AD, the most frequent cause of dementia, affects an estimated 24 million people worldwide. With very limited treatment options, scientists are looking for ways to understand the disease better.

15 Sep 2021

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity.

15 Sep 2021

New genetic classifier can predict the sensitivity of neoadjuvant chemotherapy for breast cancer

A research team by Prof. YANG Wulin and DAI Haiming from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences recently proposed a genetic classifier that can predict the sensitivity of neoadjuvant chemotherapy for breast cancer in the field of tumor molecular markers.

15 Sep 2021

Genetic capacity of the gut microbiome determines weight loss success or failure

The strongest associations with weight loss success or failure – independent of BMI – are found in the genetic capacity of the gut microbiome.

15 Sep 2021

New technology offers a faster, easier and more efficient way to study gene function

Studying the role genes play on basic biology and disease is now easier, faster and more efficient, say researchers at Baylor College of Medicine.

15 Sep 2021

Jumpcode Genomics and TGen collaborate on genomic sequencing of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

The University of Texas MD Anderson Cancer Center and SNIPR BIOME today announced a strategic collaboration to advance new CRISPR-based microbiome therapeutics to reduce immune-related adverse events (irAE) in patients being treated with combined immune checkpoint inhibitors.

13 Sep 2021

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

12 Sep 2021

New precision-guided sterile insect technique designed to control disease-spreading mosquitoes

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

11 Sep 2021

Genomic surveillance of SARS-CoV-2 reveals how the pandemic was caused in Africa

A genomic surveillance analysis of SARS-CoV-2 in Africa in the first year of the pandemic reveals that the first phase of the pandemic there was caused by importations from outside Africa, and involved limited virus spread, while the second, more deadly phase was fueled by ongoing transmission within the continent and led to emergence of many variants of concern.

10 Sep 2021

Genomics

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

UTHSC researcher receives funding to advance The Cancer Genome Atlas project

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

New genetic classifier can predict the sensitivity of neoadjuvant chemotherapy for breast cancer

Genetic capacity of the gut microbiome determines weight loss success or failure

New technology offers a faster, easier and more efficient way to study gene function

Jumpcode Genomics and TGen collaborate on genomic sequencing of SARS-CoV-2

GIST researchers unravel coordination mechanism of base excision repair

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

New precision-guided sterile insect technique designed to control disease-spreading mosquitoes

Genomic surveillance of SARS-CoV-2 reveals how the pandemic was caused in Africa

Washington University School of Medicine receives $7 million to investigate how human genome works

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

IGVF consortium receives NIH funding to study how genomic variation influences biological function

Highly extensive Gut Cell Atlas will transform research into intestinal diseases

Understanding how pathogens evolve novel virulence activities

New open-access repository of FAQs on human genomic research counters misinformation

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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