Genomics

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Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Researchers from the group of Hans Clevers (Hubrecht Institute) corrected mutations that cause cystic fibrosis in cultured human stem cells.

9 Aug 2021

Study may provide a new therapeutic target for treatment of LUAD patients

Aging-US published "A novel ferroptosis-related gene signature for prognostic prediction of patients with lung adenocarcinoma" which reported that RNA-seq transcriptome data of LUAD patients were obtained from The Cancer Genome Atlas database.

9 Aug 2021

Genetic testing in ambulatory cardiology clinics can benefit many patients

A person's genetics may hold the key to early intervention in cardiovascular disease, leading to better outcomes in patient care.

9 Aug 2021

New streamlined approach for high-coverage genome sequencing of single yeast cells

A single cell can reveal much about the biological world through genomic sequencing. Scientists can compare a single, isolated cell to other samples, analyzing the differences and similarities to better understand how the organisms originated and evolved - or even to discover entirely new species.

6 Aug 2021

New procedure increases the sensitivity to detect viruses in blood samples from healthy people

The Institute for Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the Spanish National Research Council (CSIC), has developed a procedure that increases the sensitivity to detect viruses in blood samples from healthy people, in addition to reducing the effect of contaminations.

6 Aug 2021

DNA recovered from illicit drug capsules could be used to track down criminal syndicates

Forensic scientists have for the first time shown that DNA can be recovered from the surface of capsules after just 15 seconds of contact by drug manufacturers & dealers – making it possible for law enforcement agencies to track down criminal syndicates around the world.

6 Aug 2021

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

In collaboration with Northwestern Medicine investigators, an international multi-center study has identified genetic factors associated with SARS-CoV-2 infection and COVID-19 severity, according to findings published in Nature.

6 Aug 2021

UAB researchers identify potential therapeutic target for ovarian cancer

A gene called DOT1L appears to play a role in progression and severity of ovarian cancer, and inhibitors of the DOT1L enzyme may offer a new therapeutic approach for the disease, University of Alabama at Birmingham researchers say in a study published in the journal Oncogenesis.

5 Aug 2021

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

New DNA writing technique can precisely and efficiently edit bacterial genomes

Biological engineers at MIT have devised a new way to efficiently edit bacterial genomes and program memories into bacterial cells by rewriting their DNA.

5 Aug 2021

Researchers make a breakthrough in understanding the genesis of uterine leiomyomas

Scientists at the University of Helsinki and Helsinki University Hospital have made a breakthrough in understanding the genesis of uterine leiomyomas, also called fibroids.

4 Aug 2021

Study offers genetic insights into the underlying biology of reproductive aging

The age at which women go through menopause is critical for fertility and impacts healthy ageing in women, but reproductive ageing has been difficult for scientists to study and insights into the underlying biology are limited.

4 Aug 2021

Key protein linked to both physical fitness in youth and diseases of old age

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

4 Aug 2021

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

Genetic testing and selection of embryos generated from in vitro fertilization have given rise to the controversial “designer baby” debate.

4 Aug 2021

Comprehensive study of Middle Eastern DNA reveals ancient human adaptation to agriculture, climate change

The most comprehensive study so far of genetic diversity in the Middle East has given a glimpse into the lives of ancient humans who lived through such seismic events as the development of agriculture and the formation of the Arabian Desert.

4 Aug 2021

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

In a new study, researchers at the University of Oregon's Phil and Penny Knight Campus for Accelerating Scientific Impact used start codon disruption with CRISPR-Cas9 gene editing to prevent Fuchs' corneal dystrophy in mice.

3 Aug 2021

Researchers solve century old mystery by identifying how sex cells get the right genetic mix

A new discovery explains what determines the number and position of genetic exchanges that occur in sex cells, such as pollen and eggs in plants, or sperm and eggs in humans.

3 Aug 2021

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease.

30 Jul 2021

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Increasing knowledge about genomic biomarkers has facilitated better monitoring and personalized management of patients with B-cell malignant tumors.

29 Jul 2021

Cats could be a valuable model organism for geneticists, expert says

Although cats have lived alongside humans for millennia, it remains a dogs' world. This bias has historically bled into science as well.

28 Jul 2021

Genomics

Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Study may provide a new therapeutic target for treatment of LUAD patients

Genetic testing in ambulatory cardiology clinics can benefit many patients

New streamlined approach for high-coverage genome sequencing of single yeast cells

New procedure increases the sensitivity to detect viruses in blood samples from healthy people

DNA recovered from illicit drug capsules could be used to track down criminal syndicates

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

UAB researchers identify potential therapeutic target for ovarian cancer

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

New DNA writing technique can precisely and efficiently edit bacterial genomes

Researchers make a breakthrough in understanding the genesis of uterine leiomyomas

Study offers genetic insights into the underlying biology of reproductive aging

Key protein linked to both physical fitness in youth and diseases of old age

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

Comprehensive study of Middle Eastern DNA reveals ancient human adaptation to agriculture, climate change

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

Researchers solve century old mystery by identifying how sex cells get the right genetic mix

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Cats could be a valuable model organism for geneticists, expert says

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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