Genomics

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Ancient epigenetic change deactivates some genes linked to cancer

An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research suggests.

11 Jul 2019

Comprehensive cell atlas of the human liver

The liver is one of the largest and most versatile organs of the human body. It turns sugars, proteins, and fats from our food into substances useful for the body and releases them to the cells.

11 Jul 2019

Research reveals genetic cause of deadly digestive disease in children

Nearly 10 years ago, a group of Israeli clinical researchers emailed Lawrence Berkeley National Laboratory (Berkeley Lab) geneticist Len Pennacchio to ask for his team's help in solving the mystery of a rare inherited disease that caused extreme, and sometimes fatal, chronic diarrhea in children.

11 Jul 2019

UCR scientists decode genome of black-eyed peas

UC Riverside scientists have decoded the genome of black-eyed peas, offering hope for feeding Earth's expanding population, especially as the climate changes.

10 Jul 2019

Common virus exists in over one-third of the countries worldwide

We are all the same, yet we are all different. With the participation of researcher Josefa Antón, from the University of Alicante's Department of Physiology, Genetics and Microbiology, a new study has shown how a family of tiny viruses lives in the guts of humans around the world, yet changes depending on which country we are from.

10 Jul 2019

Genomic map reveals differences underlying harmful and non-harmful fat

It's not just about how much - the location of where fat is stored in the body can have significant implications for human health.

9 Jul 2019

New research uncovers mechanism behind the newest generation of cancer drugs

New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy.

9 Jul 2019

Study reports role of cancer gene in tumor microenvironment

The tumor microenvironment is a mix of fluids, immune cells and blood vessels which envelops the tumors. Interactions between tumor cells and the TME determine the progression and fate of tumors.

4 Jul 2019

Study reveals first complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism.

4 Jul 2019

Researchers completely eliminate all traces of HIV from infected mice

For the first time, researchers have successfully removed HIV-1 DNA from the genomes of living animals, a critical step towards a potential cure for the disease.

4 Jul 2019

IDT and 3CR team up to widen access to custom solutions for genotyping screening

In the latest collaboration in a series to advocate for genomics research, Integrated DNA Technologies is teaming up with 3CR Bioscience to widen access to quality custom solutions for genotyping screening.

From Integrated DNA Technologies 3 Jul 2019

'Scissors' component of CRISPR/Cas9 sometimes gets stuck

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages' DNA.

2 Jul 2019

Scientists identify new genetic mutation behind serious skull disorder

A collaboration led by scientists at Oregon State University, the University of Oxford in the United Kingdom and Erasmus University in The Netherlands has identified a new genetic mutation behind the premature fusing of the bony plates that make up the skull.

2 Jul 2019

Research provides genomic warning flag just in time for beach season

An article published today in the Open Access journal GigaScience might make you squirm if you plan to hit the beach this summer. The article presents the draft genomes of three different jellyfish species.

30 Jun 2019

Comprehensive gene activity database could significantly reduce animal use

A comprehensive database of gene activity in mice across ten disease models, which could significantly reduce animal use worldwide, has been developed by scientists at the Francis Crick Institute, which gives a full picture of the immune response to different pathogens.

29 Jun 2019

IDT enters into strategic collaboration with Chinese medical sequencing firm ChosenMed

Integrated DNA Technologies announces that it has entered into a strategic cooperation with ChosenMed Technology (Beijing) Co., Ltd (ChosenMed), a medical sequencing firm focused on personalized medicine and transformation healthcare in China.

From Integrated DNA Technologies 28 Jun 2019

Characterizing and Isolating (Bio)macromolecular Structures using MALS

In this interview, Albena Lederer, Head of the Polymer Separation Group at the Leibniz Institute for Polymer Research, talks to News-Medical Life Sciences about the techniques and methods used to understand and analyze polymers.

From Waters | Wyatt Technology 26 Jun 2019

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Harnessing the interactions between DNA, RNA, and proteins holds much promise for detecting biomarkers, diagnosing disease, and improving cancer-targeting therapeutics. Quantifying these interactions is essential for understanding and controlling their biomolecular mechanisms.

From Waters | Wyatt Technology 26 Jun 2019

Stability Testing of Therapeutic Proteins using DLS and Machine Learning

PIPPI scientists from different fields are developing methodologies, tools, and databases to guide the rational formulation of robust protein-based therapeutics. Their overall goal is to develop a database to guide product formulation development.

From Waters | Wyatt Technology 26 Jun 2019

Researchers reveal fundamental role of protein associated with Alzheimer's

Researchers from the University of Seville, the Seville Biomedicine Institute and Lund University have been able to describe how the body responds to a component present in the brain in Alzheimer's patients.

25 Jun 2019