Genomics

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Mutations in fetal genome may contribute to premature birth

Mutations in the gene that codes for SLIT2, a protein expressed in fetal cells in placentas and involved in directing the growth of the fetal nervous system, may contribute to premature births, possibly by activating the mother’s immune system.

From PLOS ONE 14 Jun 2019

New method allows cells to be produced in shorter time and with greater success

A recent study published in the April 8 issue of Nature Chemical Biology improves on the "Cellular Reprogramming" method developed by Nobel Laureate in Medicine and Physiology Prof. Shinya Yamanaka, making it possible to produce cells in a considerably shorter time and with greater success. Yamanaka's method, which is referred to as "Cellular Reprogramming", obtains pluripotent cells, similar to the ones we know exist in the very early stages of the embryo

14 Jun 2019

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

As part of its ongoing mission to advocate for researchers in the genomics age, Integrated DNA Technologies will unveil the latest additions to its NGS catalog to the European market at the European Human Genetics Conference in Gothenburg, Sweden on 15–18 June, 2019.

From Integrated DNA Technologies 13 Jun 2019

OGT expands SureSeq NGS portfolio with a complete library preparation solution

Oxford Gene Technology (OGT), The Molecular Genetics Company, has expanded its SureSeq portfolio with a complete library preparation solution for hybridization-based target capture in NGS, making its market-leading coverage uniformity and expertise even more accessible.

From Oxford Gene Technology 13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

Researchers reveal underlying mechanism that protects genetic transcripts in cells

The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of "spliceosomes".

13 Jun 2019

Genetic variations linked with persistence of immunity after routine childhood vaccination

A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations.

12 Jun 2019

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

"Green revolution" in the early 1950s, the extensive cultivation of Dwarf Rice solves the food problem in developing countries. At present, chronic infection with hepatitis B virus (HBV) has been a major public health problem.

11 Jun 2019

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

The scientific research team from the Universidad Pablo de Olavide led by doctor José Antonio Sánchez Alcázar has published a new study in the international magazines Molecular Neorubiology and Neural Regeneration Research.

11 Jun 2019

Study looks into evolution of sex and transmissible cancer

One of the greatest enigmas of evolutionary biology is that while sex is the dominant mode of reproduction among multicellular organisms, asexual reproduction appears much more efficient and less costly.

From PLOS ONE 10 Jun 2019

Bruker launches timsTOF fleX with ESI/MALDI capability for SpatialOMx at ASMS 2019

Bruker Daltonics has launched a novel timsTOF fleX mass spectrometer which combines ESI/MALDI capability for SpatialOMx on a single instrument.

From Bruker Life Sciences Mass Spectrometry 10 Jun 2019

Human body is a mosaic pattern of DNA mutations, say researchers

Researchers have discovered that the cells of the human body aren’t clones of a single DNA sequence, but are actually a mosaic of mutations.

7 Jun 2019

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Princeton University researchers have discovered that learned behaviors can be inherited for multiple generations in C. elegans, transmitted from parent to progeny via eggs and sperm cells.

7 Jun 2019

Telomere shortening in adulthood is not caused by smoking, say researchers

A new study suggests that telomere length in adults should be regarded as a static biomarker that does not significantly change during adult life.

7 Jun 2019

NIH funds clinical trials to assess applicability of genomics for treating chronic diseases

The National Institutes of Health will fund clinical trials to assess the benefits, applicability and efficacy of applying genomic medicine interventions to improve management of diseases such as high blood pressure, depression and chronic pain.

6 Jun 2019

Scientists successfully carry out gene editing in vivo

Scientists at Harvard University have successfully proven that stem cells can be edited inside the body, rather than in a petri dish.

5 Jun 2019

MammaPrint and BluePrint identify critical aspects of tumor biology in African-American breast cancer patients

Agendia, Inc., a world leader in precision oncology, today announced the presentation of study results for BluePrint and MammaPrint use in identifying African-American women with hormone receptor positive tumors that have different genomic subtypes and risk than Caucasian women.

4 Jun 2019

Genomics

Mutations in fetal genome may contribute to premature birth

New method allows cells to be produced in shorter time and with greater success

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

OGT expands SureSeq NGS portfolio with a complete library preparation solution

New technology harnesses bacterial jumping genes for precise DNA integration

Researchers reveal underlying mechanism that protects genetic transcripts in cells

Genetic variations linked with persistence of immunity after routine childhood vaccination

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

Study looks into evolution of sex and transmissible cancer

Bruker launches timsTOF fleX with ESI/MALDI capability for SpatialOMx at ASMS 2019

Human body is a mosaic pattern of DNA mutations, say researchers

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Telomere shortening in adulthood is not caused by smoking, say researchers

NIH funds clinical trials to assess applicability of genomics for treating chronic diseases

Scientists successfully carry out gene editing in vivo

MammaPrint and BluePrint identify critical aspects of tumor biology in African-American breast cancer patients

Gene variant evolved to cope with modern high-carb diets

New tool reveals how genes interact to form tissues and organisms

Study uncovers how simpler organisms manage recycling of incomplete proteins

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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