Genomics

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IDT releases new ultra-high performance CRISPR Cas12a enzyme

As an advocate for the needs of researchers working at the forefronts of genomic research, Integrated DNA Technologies releases its latest CRISPR enzyme Alt-R® Cas12a Ultra.

From Integrated DNA Technologies 31 May 2019

DNA analysis software helps detect diseases caused by genetic changes more readily

Diseases caused by genetic changes could be detected more readily thanks to an advance in DNA analysis software.

31 May 2019

New repository enables easy exchange of machine learning models for genome research

Although the importance of machine learning methods in genome research has grown steadily in recent years, researchers have often had to resort to using obsolete software.

30 May 2019

Researchers develop new technology for extracting cell development branching time

One of the greatest achievements of science in recent years is the technology for obtaining information about thousands of individual cells extracted from an organism.

30 May 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

Researchers develop new artificial intelligence tools to find cell’s true identity

Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes.

From Johns Hopkins Medicine 29 May 2019

Epigenetic research provides new approaches to cancer combination therapies

Epigenetic processes enable cells to respond to changes in their environment by regulating the activity of their genes.

28 May 2019

Five new genetic risk loci associated with maximum habitual alcohol use identified

A genome-wide association study has identified five new genetic risk loci that can pass on risk for harmful alcohol use from parents to children, and confirmed one previously identified risk locus.

28 May 2019

Researchers shed light on evolution and diversity of Leptospira bacteria

Leptospirosis is an emerging zoonotic disease that affects more than one million people around the world each year.

28 May 2019

Study yields insights into evolutionary dynamics between bacteria and human hosts

Researchers have discovered that humans and great apes possess a receptor on their cells that detects metabolites from bacteria commonly found in fermented foods and triggers movement of immune cells.

From PLOS ONE 28 May 2019

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells.

28 May 2019

Large-scale genomic sequencing narrows search for Strep A vaccine

The global search for a group A streptococcal (Strep A) vaccine has narrowed after researchers identified a common gene signature in almost all global Strep A strains by sequencing thousands of genomes in a project spanning 10 years and more than 20 countries.

28 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Researchers get one step closer to global Strep A vaccine

The search for a global Strep A vaccine has narrowed after researchers sequenced the DNA of more than 2000 Group A Streptococcus samples from around the world.

27 May 2019

Mutations in 'junk' DNA can cause autism, study shows

Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called 'junk' DNA can cause autism.

27 May 2019

Mites and ticks are part of the same evolutionary line, research shows

Scientists from the University of Bristol and the Natural History Museum in London have reconstructed the evolutionary history of the chelicerates, the mega-diverse group of 110,000 arthropods that includes spiders, scorpions, mites and ticks.

27 May 2019

Artificial intelligence technique identifies new class of mutations behind autism

Many mutations in DNA that contribute to disease are not in actual genes but instead lie in the 99% of the genome once considered "junk." Even though scientists have recently come to understand that these vast stretches of DNA do in fact play critical roles, deciphering these effects on a wide scale has been impossible until now.

27 May 2019

Newly approved gene therapy for SMA is based on delivery vehicle discovered by Penn expert

James Wilson, MD, PhD, recalls being struck by the devastating toll of rare diseases as a young physician in the 1980s. He set out on a path to correct the genes that cause these conditions, including spinal muscle atrophy (SMA), the most common inherited fatal disease in infants.

25 May 2019

Are fruit fly 'avatars' the next step in personalized medicine?

Researchers have created fruit fly “avatars” that have helped to guide treatment for a man who had terminal colon cancer.

24 May 2019

Cornell University-led study creates new standard genome for widely researched worm

A new Cornell University-led study finds that the genome for a widely researched worm, on which countless studies are based, was flawed. Now, a fresh genome sequence will set the record straight and improve the accuracy of future research.

24 May 2019

Genomics

IDT releases new ultra-high performance CRISPR Cas12a enzyme

DNA analysis software helps detect diseases caused by genetic changes more readily

New repository enables easy exchange of machine learning models for genome research

Researchers develop new technology for extracting cell development branching time

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers develop new artificial intelligence tools to find cell’s true identity

Epigenetic research provides new approaches to cancer combination therapies

Five new genetic risk loci associated with maximum habitual alcohol use identified

Researchers shed light on evolution and diversity of Leptospira bacteria

Study yields insights into evolutionary dynamics between bacteria and human hosts

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Large-scale genomic sequencing narrows search for Strep A vaccine

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Researchers get one step closer to global Strep A vaccine

Mutations in 'junk' DNA can cause autism, study shows

Mites and ticks are part of the same evolutionary line, research shows

Artificial intelligence technique identifies new class of mutations behind autism

Newly approved gene therapy for SMA is based on delivery vehicle discovered by Penn expert

Are fruit fly 'avatars' the next step in personalized medicine?

Cornell University-led study creates new standard genome for widely researched worm

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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