Genomics

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BHCGC consortium to play key role in NIH's large-scale effort to advance precision medicine

The Baylor College of Medicine Human Genome Sequencing Center today announced participation in the National Institutes of Health All of Us Research Program, a large-scale effort to advance precision medicine.

27 Sep 2018

Not all P53 mutations cause skin cancer

Today, scientists have explained for the first time why not all UV-induced, P53 mutated skin cells develop into cancer.

27 Sep 2018

New approach promises to forecast cultivar resistance at much earlier stage

Bacterial wilt devastates food crops all over the world. It destroys major crop plants such as tomatoes, potatoes, bananas, ginger and pepper. It occurs in many countries and attacks over 200 plant species.

27 Sep 2018

Researchers identify single gene that regulates highly diverse ladybird color patterns

Many ladybirds have attractive color patterns consisting of black and red. This prominent color pattern is thought to function as a warning that indicates to predators that they are very bitter and unpalatable.

27 Sep 2018

NIH-funded genome centers to speed up breakthroughs in precision medicine

The All of Us Research Program awarded funds totaling $28.6 million to establish three genome centers around the country. These centers will begin to generate genomic data from biosamples contributed by the program's participants.

26 Sep 2018

Genetic testing can play a substantial role in medical management

Genetic testing can play a substantial role in medical management by uncovering changes in genes that are associated with an increased risk for hereditary cancers.

26 Sep 2018

Researchers now confirm that genome duplication drives evolution of species

Many wild and cultivated plants arise through the combination of two different species. The genome of these so-called polyploid species often consists of a quadruple set of chromosomes - a double set for each parental species - and thus has about twice as many genes as the original species.

25 Sep 2018

Environmentally-induced gene activity influences IQ test performance

Is there a link between differences in IQ test performance and the activity of certain genes? Researchers from Charité - Universitätsmedizin Berlin have shown that modifications in the structure of a specific gene have a negative impact on individual test performance.

25 Sep 2018

Genomic ‘islands’ evolved from viruses can be converted into ‘anti-bacterial drones’

Genomic "islands" that evolved from viruses can be converted into "drones" that disable Staphylococcus aureus, bacteria that are often resistant to antibiotics and pose a threat to safe hospital care, a new study finds.

25 Sep 2018

Ecstasy drug makes octopuses more social

When people take MDMA, the drug popularly known as ecstasy, a rush of serotonin, dopamine, and oxytocin produces feelings of emotional closeness and euphoria, making people more interested than they would normally be in connecting and sharing with other people.

24 Sep 2018

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. This gene-editing tool CRISPR-Cas9 holds promise for correcting defects inside individual cells and potentially healing or preventing many human ailments.

20 Sep 2018

Novel mathematical approach uncovers existence of unsuspected biological cycles

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.

20 Sep 2018

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

The human brain is exceedingly complex, consisting of various regions with particular functions and approximately 100 billion neurons. This complexity has presented a major challenge in understanding this organ and how it develops, particularly in view of the ethical issues associated with research on humans.

20 Sep 2018

New research suggests link between PFAS chemicals and hyperthyroidism in pet cats

New research suggests that there may be a link between higher levels of per- and polyfluoroalkyl substances in the environment and higher levels of hyperthyroidism in pet cats as they age. The findings are published in

20 Sep 2018

Study finds factors within cell influencing variability in amount of protein produced

You can think of a cell in your body like a miniature factory, creating a final product called proteins, which carry out various tasks and functions.

20 Sep 2018

New study focuses on two-way gene switches controlling gene activity

Led by ICREA research professors at the Centre for Genomic Regulation, Luciano Di Croce and Marc A. Marti-Renom, the study focused on a set of genes with what's known as bivalent promoters - two-way genetic 'control switches' that are poised either to turn on in early development and rapidly drive high levels of gene activity, or to switch off and shut down the gene completely.

20 Sep 2018

Antioxidant in green tea helps sneak therapeutic RNAs into cells

Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss.

19 Sep 2018

Study finds why some human genes are more popular with biomedical researchers

Historical bias is a key reason why biomedical researchers continue to study the same 10 percent of all human genes while ignoring many genes known to play roles in disease, according to a study publishing September 18 in the open access journal PLOS Biology, led by Thomas Stoeger and Luís Amaral of Northwestern University, and colleagues. This bias is bolstered by research funding mechanisms and social forces.

19 Sep 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

Scientists discover new molecules that work together to remove unwanted DNA

Scientists have discovered a new family of molecules that work together to precisely remove unwanted DNA during reproduction in single-celled, freshwater organisms called ciliates.

19 Sep 2018